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WorksheetsMCB Exam 4 Review
Total questions: 15
Worksheet time: 8mins
Damage by UV light is repaired by which mechanism?
Nucleotide excision repair
Single stranded basic repair
Double stranded break repair
Mismatch repair
DNA damage by chemotherapy or radiotherapy is repaired by which mechanism?
Nucleotide excision repair
Single stranded basic repair
Double stranded break repair
Mismatch repair
DNA replication errors are fixed by which mechanism?
Nucleotide excision repair
Single stranded base excision repair
Double stranded break repair
Mismatch repair
DNA damage caused by alkylating agents is repaired by which mechanism?
Nucleotide excision repair
Single stranded basic repair
Double stranded break repair
Mismatch repair
What if growth factors are not present in G1?
If cyclin D synthesis in G1 is unregulated what happens?
What happens if Rb is inactivated?
Where does Cyclin B works (which phase) and what would happen if you could not degrade it?
G1 checkpoint checks for?
Cell size and nutrients
growth factors present
DNA structure
One replication
G2 checkpoint checks for?
Cell size
Correct DNA replication
DNA damage
Nutrients
M checkpoint checks for
DNA damage
chromosomal attachment to spindle
Cell size
chromosome alignment
S checkpoint checks for?
Only one replication DNA
Correct alignment at anaphase
DNA damage
Growth factors
What does interpolar microtubules do?
They connect from centriole to centriole
They connect from centriole to membrane
They connect form the spindle and attach to kinetochores
What does astral microtubules do?
They connect from centriole to centriole
They connect from centriole to membrane
They connect form the spindle and attach to kinetochores
What is true about APC/C?
It is an E3 ubiquitin ligase that marks target cell cycle proteins for degradation by the proteasomes
Works during mitosis
Helps check for DNA damage in G2
It is phosphorylated by MPF
