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WorksheetsToxicology Finals
Total questions: 85
Worksheet time: 28mins
Name
Class
Date
1.
In the Iliad, Homer described opium as
a)
Bringer of Happiness
b)
A drink fit for Buddha
c)
Bringer of Sleep
d)
Remedy that promotes vivid dreams
2.
Laudanum means
a)
Something to be praised
b)
Tincture of opium
c)
Tincture of morphine
d)
all of the choices
3.
Diacetylmorphine is aldo known as
a)
Codeine
b)
Heroin
c)
Thebaine
d)
Narcotine
4.
Pain receptors are also known as
a)
Kappa receptors
b)
Coupled receptors
c)
Nocireceptors
d)
G-proteins
5.
Which of the following is NOT an opium alkaloid
a)
Apomorphine
b)
Thebaine
c)
Narcotine
d)
Naloxone
6.
The following are opioids except
a)
Tramadol
b)
Dextromethorphan
c)
Diclofenac
d)
Methadone
7.
Opium alkaloid more effective orally than morphine with respiratory depression as major side effect
a)
Codeine
b)
Heroin
c)
Methadone
d)
Thebaine
8.
Which of the following is NOT a side effects of morphine
a)
respiratory depression
b)
constipation
c)
sedation
d)
acute pancreatitis
9.
It is the gold standard to which the structure and strength of all other opioid drugs are compared
a)
Heroin
b)
Morphine
c)
Codeine
d)
Apomorphine
10.
Major pathway for the metabolism of morphine
a)
Deamination
b)
Conjugation with glucuronic acid
c)
Sulfate conjugation
d)
Hyroxylation
11.
It’s a synthetic cathenone known as "Miaow"
a)
Methylone
b)
Mephedrone
c)
Ecstacy
d)
Dimethytryptamine
12.
What is Ecstacy chemically?
a)
methyl-methcathinone
b)
methylenedioxyprovalerone
c)
Methylenedioxymetamphetamine
d)
Phenethylamine
13.
The following compounds are stimulants EXCEPT
a)
Mephedrone
b)
Bath salts
c)
Mescaline
d)
Piperazine
14.
Opioid antagonists have strong binding affinity with this receptor
a)
Kappa recveptor
b)
Mu receptor
c)
Delta receptor
d)
Coupled receptor
15.
People exposed to toxic levels of this metal may manifest garlicky odor of breath and urine
a)
Mercury
b)
Arsenic
c)
Lead
d)
Antimony
16.
The most poisonous form of mercury
a)
Elemental mercury
b)
Organic Mercury
c)
Precipitated mercury
d)
Mercuric sulfate
17.
A highly toxic substance classified as an antipyretic that can cause methemoglobinemia?
a)
Acetaminophen
b)
Mefenamic acid
c)
Phenacetine
d)
Acetanilide
18.
Antidote for paracetamol poisoning
a)
N-acetylcysteine
b)
Glutathione
c)
Acetylcystine
d)
N-acetylcarboxylamine
19.
A common OTC cough medicine that at high doses may produce dissociative hallucinations
a)
Carboxymethylcysteine
b)
Diphenhydramine
c)
Dextromethorphan
d)
Codeine
20.
Metal used in car batteries
a)
Lead
b)
Cadmium
c)
Copper
d)
Zinc
21.
Another name for Pink disease
a)
Acrodynia
b)
Erethema
c)
Paresthesia
d)
Circulatory collapse
22.
Metal used for making low-melting point glass for highly reflective lenses
a)
Tin
b)
Thallium
c)
Zinc
d)
Selenium
23.
Volatile poison that may cause blindness when ingested
a)
Ethanol
b)
Phenol
c)
Chloroform
d)
Methanol
24.
Paints containing this metal are used because of their bright colors and weather resistant properties
a)
Lead
b)
Copper
c)
Mercury
d)
Thallium
25.
The most dangerous organic tin substance
a)
Stannic acid
b)
Triethyltin
c)
Stannous oxide
d)
Tin oxide
26.
Agency mandated to evaluate and monitor work related injuries and illnesses as occupational hazards
a)
FDA
b)
EPA
c)
NIOSH
d)
NIH
27.
The first opium war resulted in the ceding of this territory to Britain by China
a)
Macau
b)
Hongkong
c)
Taiwan
d)
Singapore
28.
Bhopal incident is an environmental disaster caused by this chemical
a)
Arsenic
b)
Sodium cyanide
c)
Methylisocyanate
d)
Dioxin
29.
Gum line with blue-black discoloration (Burton's line) indicates poisoning with this metal
a)
Lead
b)
Mercury
c)
Arsenic
d)
Cyanide
30.
Also known as the universal antidote
a)
Sodium bicarbonate
b)
Milk
c)
Activated charcoal
d)
Methylene blue
31.
Presence of Mees line is a characteristic symptom of poisoning with this group
a)
Volatile poisons
b)
Metals
c)
Alkaloids
d)
PAHs
32.
Form of lead that is still used as additive in gasoline
a)
Tetraethyl lead
b)
Lead oxide
c)
alkylated lead
d)
Methyl lead
33.
This is a colorless gas formed when arsenic comes in contact with hydrogen or reducing agents
a)
Arsenous oxide
b)
Arsenic oxide
c)
Arsine
d)
Hypoarsenate
34.
This metal can be found in keratin-rich tissues even when exposure to it has ceased for 2-4 weeks
a)
Arsenic
b)
Mercury
c)
Lead
d)
Cadmium
35.
Enzyme responsible for the conversion of Acetaminophen to the toxic metabolite NAPQI
a)
CYP3A4
b)
CYP2E1
c)
CYP2A2
d)
CYP1E1
36.
These are formed in nature as a result of incomplete combustion.
a)
PAHs
b)
Formaldehyde
c)
Nitrobenze
d)
Aniline
37.
Chloracne is a result of poisoning with this chemical
a)
Benzene
b)
Ethyleneglycol
c)
Dioxin
d)
Aniline
38.
An poison that can be used as a protein precipitant and is used to preserve animal or organ samples
a)
Chloroform
b)
Ethyleneglycol
c)
Methanol
d)
Methanal
39.
Drug of choice for chronic alcohol poisoning
a)
Folinic acid
b)
Disulfiram
c)
Thiazole
d)
Fomipizole
40.
Antidote for methemoglobinemia
a)
Methylene blue
b)
Dimercaprol
c)
Oxygen therapy
d)
Crystal violet
41.
Studies showed that exposure to asbestos via inhalation can cause this form of cancer
a)
Meningioma
b)
Ague
c)
Mesothelioma
d)
Asbestosis
42.
Another name for methyl morphine
a)
Thebaine
b)
Heroin
c)
Codeine
d)
Apomorphine
43.
Absence of pain without losing consciousness
a)
Anesthesia
b)
Analgesia
c)
Apyrexia
d)
Paresthesia
44.
An opioid which is 1,000x stronger than morphine
a)
Methadone
b)
Codeine
c)
Carfentanyl
d)
Fentanyl
45.
An opioid analgesic which is 10,000x more potent than morphine used as a tranquilizer for large animals.
a)
Methadone
b)
Codeine
c)
Carfentanyl
d)
Fentanyl
46.
An example of an opioid antagonist
a)
Narceine
b)
Naloxone
c)
Thebaine
d)
Narcotine
47.
He was known to be executed with the use of hemlock for teaching radical ideas to youth.
a)
Socrates
b)
Paracelsus
c)
Orfila
d)
Ehrlich
48.
Known as the father of modern toxicology
a)
Socrates
b)
Paracelsus
c)
Orfila
d)
Ehrlich
49.
Known as the father of forensic toxicology
a)
Socrates
b)
Paracelsus
c)
Orfila
d)
Ehrlich
50.
The study of adverse effects of chemicals on living organisms
a)
Pharmacology
b)
Toxicology
c)
Pharmakokinetics
d)
Pharmacodynamics
51.
Another name for Tincture of Morphine
a)
Paregoric
b)
Laudanum
c)
Aqua regia
d)
Aqua Toffana
52.
Another name for Camphorated Tincture of Morphine
a)
Paregoric
b)
Laudanum
c)
Aqua regia
d)
Aqua Toffana
53.
Codeine is producted from morphine by this process
a)
Hydrolysis
b)
Acetylation
c)
Methylation
d)
Reduction
54.
He wrote a treatise called De Historia Plantarum
a)
Paracelsus
b)
Dioscorides
c)
Socrates
d)
Theophrastus
55.
The laboratory confirmatory test for morphine.
a)
Thalleoquin Test
b)
Marquis test
c)
Mayers Test
d)
Mandelin's test
56.
Specific test for quinine
a)
Thalleoquin Test
b)
Marquis test
c)
Mayers Test
d)
Mandelin's test
57.
The treaty legalized opium importation to China in 1858.
a)
Treaty of Tientsin
b)
Treaty of Nanjing
c)
Treaty of Wuhan
d)
Treaty of Yangtze
58.
Isolated morphine from opium in 1805
a)
Pauling
b)
Serturner
c)
Ehrlich
d)
Lambert
59.
Oldest known writing which included poisons like hemlock and arrow poison
a)
Ebers papyrus
b)
De Historia Plantarum
c)
De Materia Medica
d)
De Morbis Artificum
60.
Test for arsenic
a)
Ninhydrin test
b)
Marsh Test
c)
Mayers Test
d)
Marquis Test
61.
Developed staining procedures to observe cells andtissues and how toxicnts affect living organisms
a)
Pauling
b)
Serturner
c)
Ehrlich
d)
Lambert
62.
Circulatory collapse in newborn infants associated with excessively high levels of chloramphenicol
a)
Kernicterus
b)
Gray baby syndrome
c)
Spina bifida
d)
Epstein anomaly
63.
Linked scrotal cancer among chimney sweeps and benzo(a)-pyrene in soot
a)
Hill
b)
Carson
c)
Pott
d)
Ramazzini
64.
Alarmed the public about dangers of pesticides in her book "The Silent Spring:"
a)
Hill
b)
Carson
c)
Pott
d)
Ramazzini
65.
It is the potential of a substance to cause damage
a)
risk
b)
hazard
c)
potency
d)
toxicity
66.
It is a measure of the probability that harm will occur under defined conditions of exposure to chemicals
a)
risk
b)
hazard
c)
potency
d)
toxicity
67.
Large flat molecules built of a collecion of fused aromatic rings and formed via incomplete combustion
a)
Nitrosoamines
b)
CFCs
c)
PAHs
d)
Organic metals
68.
It is a condition resulting from Dioxin poisoning
a)
Keratosis
b)
Contact dermatitis
c)
Leukemia
d)
Chloracne
69.
It is classified as an herbicide and defoliant used during the Vietnam war
a)
Dioxin
b)
Malathion
c)
Agent orange
d)
Arsine
70.
Formaldehyde is also known by this name
a)
Methanal
b)
Ethanal
c)
Formamide
d)
Carbolic acid
71.
Inhibits alcohol dehydrogenase but may also inhibit the metabolism of methyl alcohol to its toxic metabolites.
a)
Fomepizole
b)
Disulfiram
c)
Folinic acid
d)
Folic acid
72.
It is commonly encountered in antifreeze solutions and has been used illicitly to sweeten some wines
a)
Chloroform
b)
Ethylene glycol
c)
Ethanol
d)
Methanol
73.
Antidote for methemoglobinemia caused by nitrobenzene
a)
Hyperbaric oxygen
b)
Methylene blue
c)
Iron supplementation
d)
Gastric lavage
74.
Mesothelioma is a result of poisoning with this chemical
a)
Nitrobenze
b)
Arsenic
c)
Asbestos
d)
Silicone dioxide
75.
This is a key enzyme in the formation of NADPH needed for a number of metabloc reactions
a)
CYP450
b)
G6P dehydrogenase
c)
alcohol dehydrogenase
d)
Flavin monooxygenase
76.
This product in the urine can be an indicator of nitrobenzene poisong
a)
p-nitrophenol
b)
p-nitrobenzene
c)
aniline
d)
benzene
77.
It is considered to be a useful biomarker of exposure to environmental PAHs
a)
CYP3A4
b)
CYP2E1
c)
CYP2A2
d)
CYP1A1
78.
The first three metals in the 2017 most toxic hazardous substance EXCEPT
a)
arsenic
b)
lead
c)
cadmium
d)
mercury
79.
Calculation of risk include the consideration of the following EXCEPT
a)
hazard
b)
time
c)
exposure
d)
dosage form
80.
Drugs which compete for the binding sites of warfarin in albumin increase the level of free warfarin causing fatal hemorrhage is an example of
a)
addition
b)
potentiation
c)
anatagonism
d)
synergism
81.
This evidence is generally acceptable or admissible in court
a)
lie detector test result
b)
blood pressure changes
c)
shoe print
d)
hair sample
82.
Corpus delecti means
a)
decomposing body
b)
body of evidence
c)
tast meat
d)
proof of poisoning
83.
It is a complex, chronic, relapsing brain disease characterized by compulsive, and at times, uncontrollable drug craving, seeking, and use
a)
substance use disorder
b)
addiction
c)
dependence
d)
tolerance
84.
It is a state in which a person no longer responds to a drug as they did before, and a higher dose is required to achieve the same effect.
a)
Addiction
b)
Tolerance
c)
Craving
d)
Dependence
85.
The main active ingredient in marijuana
a)
Tetrahydrocannabinol
b)
Canabinine
c)
hydroxycannabinol
d)
tetrahydrocodone
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