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Corynebacterium diphtheria.

Total questions: 18

Worksheet time: 9mins

Name
Class
Date
1.

To determine the toxigenicity of the pathogens isolated from the patients, the diphtheria cultures were plated on a Petri dish with nutrient agar on both sides of the centrally located strip of filter paper moistened with antidiphtheria antitoxic serum. After the incubation of the crops in the agar between the individual cultures and a strip of filter paper, the areas of turbidity of the medium were found to be mixed darkly. What immunological reaction was performed?

a)

The precipitation reaction in the gel.

b)

Coombs reaction.

c)

Agglutination reaction.

d)

The ring precipitation reaction.

e)

Reaction by opsonization.

2.

In the children's department of the infectious clinic, the boy is diagnosed with "diphtheria."

What drug should be administered to the patient first?

a)

antiparasitic antitoxic serum.

b)

diphtheria toxoid.

c)

DTP (diphteria and tetanus toxoids and pertussis vaccine).

d)

DTV (diphtheria tetanus vaccine).

e)

ТАВte.

3.

When sowing material from the pharynx from the patient with angina to blood-tellurite agar, colonies with a diameter of 4-5 mm, of gray color, radially striated (in the form of rosettes) grew. Under the microscope, gram-positive rods with club-shaped thickenings at the ends, located in the form of rose-rooted fingers. What are microorganisms?

a)

Corynebacterium diphtheria.

b)

Clostridium botulism.

c)

Diphtheroids

d)

Streptococci.

e)

Streptobacilli.

4.

When the 4-year child was examined for complaints of general weakness, sore throat and difficulty swallowing, the doctor suspected diphtheria and sent the material to the bacteriological laboratory. On which differential diagnostic nutrient medium should they sow the material for the isolation of the causative agent of diphtheria?

a)

Blood-tellurite agar

b)

Endo medium

c)

Ploskirev medium

d)

Saburo medium

e)

Levenshtein-Jensen medium

5.

The otolaryngologist at the examination of the patient noted flushing, a significant swelling of the tonsils with a gray bloom on them. During microscopy plaque was found, Gram-positive rods are located at an angle to each other. What kind of disease should be suspected?

a)

Diphtheria

b)

Angina

c)

Scarlet fever

d)

Meningonazopharyngitis

e)

Epidemic Parotitis

6.

A patient with suspicion for diphtheria during a bacterioscopic examination of a smear from the pharynx revealed rod-shaped bacteria with the grains of the volute. Which etiotropic drug is the drug of choice in this case?

a)

Antidiphtheria antitoxic serum

b)

Bacteriophage

c)

Diphtheria toxoid

d)

Eubiotics

e)

Interferon

7.

From the throat of a child with a suspicion for diphtheria was isolated a clear culture of microorganisms and it was studied for its morphological, tinctorial, cultural and biochemical properties, which turned out to be typical for diphtheria pathogens. What research should be done to give an opinion that a pathogenic diphtheria bacillus has been isolated?

a)

Determination of toxigenic properties.

b)

Determination of proteolytic properties.

c)

Determination of urease activity.

d)

Determination of cystine activity.

e)

Determination of the ability to break down starch

8.

To determine the toxigenicity of diphtheria bacillus on a dense nutrient medium, a strip of filter paper impregnated with antitoxic diphtheria serum was placed, and next to it, the studied culture of microbes and a known toxigenic strain were sowed in the form of plaques. If the studied culture of microbes produces exotoxin, then they form:

a)

Lines of precipitation

b)

Areas of hemolysis

c)

Diffuse cloud zones

d)

Zones of lecithotylase activity

e)

Ring of precipitation

9.

In the case of bacterioscopic examination of smears from the pharynx stained by Neisser, sticks were found, located at an angle to each other with volutein grains at the ends. What kind of microorganisms can be considered?

a)

Corynebacterium diphtheriae

b)

Legionella pneumophila

c)

Bordetella pertussis

d)

Treponema pallidum

e)

Yersinia pestis

10.

Among the children of the school there were cases of angina. When microscopic smears, prepared from a material taken from a tampon with tonsils and stained by Neisser, thin yellow sticks with dark blue grains at the ends were found. The sticks were arranged in the form of a Roman five. What infection can be suspected in this case?

a)

Diptheria

b)

Infectious mononucleosis

c)

Listeriosis

d)

Tonsillitis

e)

Scarlatinu

11.

For the causative agent of diphtheria, it is characteristic:

a)

the presence of spores;

b)

the presence of capsules;

c)

the relative position of cells at an angle to each other;

d)

the presence of grains of volutin

12.

Major factor The pathogenicity of Corynebacterium diphteriae is:

a)

exotoxin;

b)

endotoxin;

c)

LPS of the cell wall;

d)

pills

e)

protein M.

13.

Diphtheria causative agent possesses:

a)

urease activity;

b)

toxicogenic properties;

c)

cystinase activity;

d)

hemolytic activity;

e)

the ability to reduce nitrates to nitrites.

14.

In laboratory diagnosis of diphtheria:

a)

the material before the study is treated with acid to eliminate the associated flora;

b)

the material is selected before the start of antibiotic therapy;

c)

material should be transported and stored before sowing

at a temperature of 37 ° C;

d)

material previously centrifuged.

15.

For primary cultivation corynebacterium diphtheria

use:

a)

medium of Borde-Jangu;

b)

medium of Klauberg;

c)

medium of Levenshtein-Jensen;

d)

serum agar with ristomycin;

e)

blood agar.

16.

To identify the causative agent of diphtheria in a smear, you can use coloring:

a)

according to Gram;

b)

according to Neisser;

c)

according to Zil-Nielsen;

d)

on Ozheshke.

17.

C.diphtheriae are used to identify signs:

a)

morphological;

b)

cultural;

c)

biochemical;

d)

serological;

e)

toxigenic.

18.

The toxicity of diphtheria is determined using:

a)

precipitation reactions in agar;

b)

neutralization reactions of anti-bodies;

c)

agglutination reactions.