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WorksheetsFormative Round 3
Total questions: 20
Worksheet time: 10mins
Name
Class
Date
1.
For the treatment of Helicobacter Pylori, Triple Therapy is:
a)
Clarithromycin, Amoxicillin, Metronidazole
b)
Clarithromycin, Amoxicillin, Esomeprazole
c)
Gentamicin, Amoxicillin, Clarithromycin
d)
Paracetamol, Amoxicillin, Ibuprofen
2.
Which of the following is NOT a factor responsible for the development of acne lesions?
a)
Excess sebum production
b)
P. Acnes
c)
Hypokeratinisation
d)
Inflammation
3.
Which is the infective form of Giardia?
a)
Oocyte
b)
Trophozoite
c)
Cysticercoid
d)
Cyst
4.
Which test can distinguish between natural post-infection immunity & post-vaccination immunity?
a)
HBV surface antigen (HBsAg)
b)
Antibody to HBV core antigen (anti-HBc)
c)
Antibody to HBsAg (anti-HBs)
d)
HBV e antigen (HBeAg)
5.
What is the most common mutation in cystic fibrosis?
a)
CF508
b)
Delta F508
c)
Delta E007
d)
Gamma 607
6.
Hypoglycaemia will most likely cause which of the following clinical signs and symptoms?
a)
Trembling, sweating, fever
b)
Trembling, sweating, tachycardia
c)
Pallor, sweating, hypotension
d)
Polyuria, abdominal pain, fever
7.
Which is not one of the elements of open disclosure:
a)
Explain the impact of the mistake
b)
Apologise to your team
c)
Listen to the patient's story
d)
Explain what happened
8.
To be a good rule out test the test should have a:
a)
High Sensitivity
b)
Low Sensitivity
c)
High Specificity
d)
Low Specificity
9.
What is the recommended upper limit of alcohol per day in grams for females and males?
a)
Females 1 gram, Males 2 grams
b)
Females 10 grams, Males 20 grams
c)
Females 20 grams, Males 40 grams
d)
Females 20 grams, males 20 grams
10.
Social determinants of health include (choose best answer):
a)
Medical history, family medical history, current treatments
b)
Doc-patient relationship, patient autonomy, nonmaleficence
c)
Education, access to services, housing
d)
hand hygiene, genetic predisposition, climate change
11.
Which statement is true of competitive antagonists?
a)
They have efficacy and intrinsic activity
b)
They shift agonist dose curve to the left
c)
Effects can be overcome via increasing substrate concentration
d)
They reduce the max velocity of the enzyme
12.
Which statement about drug metabolism is true?
a)
Phase 1 involves: oxidation, reduction, hydrolysis.
b)
A pro drug is always active before metabolism
c)
phase 2 reactions make metabolites more lipid soluble.
d)
Conjugates of phase 2 are usually still active.
13.
“If you were to eat a bucket load of NSAIDs every day, what will be the effect(s)?”
a)
Inhibition of cyclooxygenase
b)
Increased production of prostaglandins
c)
Increased production of HCl in the stomach
d)
All of the above
14.
Ranitidine primarily acts on:
a)
Mast cells
b)
Chief cells
c)
Parietal cells
d)
ECL cells
15.
When giving a drug regularly, how many half-lives does it take to reach a steady state?
a)
It takes about 6 half-lives to reach
b)
It takes about 8 half-lives to reach
c)
It takes about 10 half-lives to reach
d)
It takes about 5 half-lives to reach
16.
Therapeutic Index of a drug is calculated from the dose that _______ to the dose that ________.
a)
is the smallest possible; is the largest possible
b)
has therapeutic effect in all patients; has no side effects
c)
will manage the disease; will allow the disease to continue
d)
is toxic in half pts; is therapeutic in half pts
17.
Which of the following is not true about tamoxifen?
a)
Prodrug
b)
Metabolised by CYP3A4
c)
Metabolised to endoxifen
d)
Stimulates oestrogen receptors in the uterus
18.
Build up of what causes a cough in patients taking ACE inhibitors?
a)
Bradykinin
b)
PGI2
c)
Angiotensin II
d)
Angiotensin I
19.
Which one of the following medications irreversibly binds to H+ / K+ ATPase?
a)
β2 agonist
b)
H1 Antagonist
c)
H2 Antagonist
d)
Proton Pump Inhibitor
20.
Which one of the following medications is used in a sweat test for cystic fibrosis?
a)
Acetylcholine
b)
Pirenzepine
c)
Pilocarpine
d)
Atropine
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