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DNA Replication

Total questions: 30

Worksheet time: 15mins

Name
Class
Date
1.

The picture below shows an enzyme unwinding and unzipping DNA.

​What is the name of this enzyme?

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

2.

Which enzyme is responsible for adding the free nucleotides to the replicating DNA? ​

a)

DNA Helicase

b)

DNA Ligase

c)

DNA polyermase

d)

RNA Polymerase

3.

Which is the first step?

a)

DNA Helicase unwinds original DNA strand

b)

RNA Primase lays down RNA primer for new nucleotide bases.

c)

DNA polymerase builds new strands by bring in new nucleotide bases.

d)

Ligase knits together fragments on lagging strand

4.

Which letter in the picture below depicts the leading strand in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

5.

Which letter in the picture below depicts the replication fork in DNA replication?

a)

A

b)

C

c)

B

d)

None of the above

6.

Okazaki fragments appear on which strand of DNA during DNA replication?

a)

lagging

b)

leading

7.
The two strands of a DNA molecule are held together by ________ bonds between their base pairs.
a)
covalent
b)
hydrogen
c)
ionic
d)
peptide
8.
What part of a nucleotide accounts for the genetic variation between individuals?
a)
phosphate
b)
nitrogenous base
c)
deoxyribose
d)
sugar
9.
If a segment of double-stranded DNA has 40 percent A, how much of it is C?
a)
40
b)
10
c)
15
d)
20
10.
If one strand of DNA has the sequence TTACCG, the sequence of the other strand of the same molecule will be
a)
AATGGC
b)
TTACCG
c)
AACGGC
d)
AATGGG
11.
Once replication in a DNA molecule is complete, each new DNA molecule contains 
a)
two new strands.
b)
3 exact copies of strands.
c)
one new strand and one old.
d)
two old strands.
12.
Why is DNA important?
a)
it is very small and very complicated
b)
it's in everything
c)
it serves as the blueprint for traits of all living things
d)
because we eat it every day for energy
13.
What are the 4 nitrogen bases?
a)
adenine, thymine, cytoplasm, and guanine
b)
adenine, thymine cytosine, and guanine
c)
adenine, thymine, cytosine, and gylcerol
d)
adenine, thymine, cytosine, and glucose
14.
Name this structure
a)
double helix
b)
nucelotide
c)
twisted ladder
d)
hydrogen bond
15.
When does replication occur?
a)
G0 phase
b)
G1 phase
c)
G2 phase
d)
S phase
16.
Any change in the sequence of DNA is...
a)
transgenic shift
b)
Single Genotype
c)
Monohybrid Trait
d)
Mutation
17.

The fragments on the lagging strand that are made up of repeating segments of DNA and RNA Primers

a)

okazaki fragments

b)

Primase

c)

Polymerase

d)

unused DNA

18.

Which of the following best describes the arrangement of the sides of the DNA molecule

a)

Bonding

b)

Alternating

c)

Anitparallel

d)

Parallel

19.

DNA polymerase moves in the _________ to ____________ direction

a)

3' to 5'

b)

easiest

c)

5" to 3"

d)

9 to 5

20.

Enzyme that connects the DNA to the backbone (glues)

a)

Ligase

b)

Polymerase

c)

Helicase

d)

Primase

21.

Enzyme that breaks hydrogen bonds (unzips)

a)

Ligase

b)

Polymerase

c)

Primase

d)

Helicase

22.

The new DNA strand formed after DNA replication is an exact copy of its parent strand

a)

True

b)

False

23.

#1 in the picture above (builder)

a)

Helicase

b)

Primase

c)

Polymerase

d)

Ligase

24.
If a strand reads:
3' A A A T T T C 5'
The matching strand would read...
a)
5' T T T A A A G 3'
b)
3' T T T A A A G 5'
c)
5' A A A T T T C 3'
d)
3' U U U A A A G 5'
25.
This picture is illustrating the ____ nature of DNA.
a)
anti-parallel
b)
deoxyribosic
c)
helical
d)
radioactive
26.
Polymerase is able to replicate the new DNA ______ along the leading strand.
a)
continuously
b)
only in short fragments
c)
very slowly
d)
prokaryotically
27.
A DNA nucleotide contains all of the following, except...
a)
Deoxyribose
b)
Phosphate group
c)
Nitrogenous base
d)
Cholesterol
28.
What is the shape of DNA?
a)
Double helix
b)
Triple helix
c)
Flat, bilayer
d)
Three-pronged rigid ladder
29.

Which enzyme helps to loosen and uncoil the DNA strand to prepare for replication?

a)

RNA Polymerase

b)

Nuclease

c)

Gyrase

d)

Helicase

30.
If the percentage of DNA is made of 30% Thymine, what is the correct percentage of Guanine?
a)
30
b)
15
c)
20
d)
60