WorksheetsGene Expression and Regulation
Total questions: 20
Worksheet time: 7mins
A mutation within the promoter region has occurred. What would potentially happen to transcription rate?
Mutated promoters decrease the rate of transcription.
Mutated promoters increase the rate of transcription.
Mutated promoters can increase or decrease the rate of transcription.
Mutated promoters cease transcription of the adjacent gene.
A lack of this nonprotein molecule would result in the inability of the cell to "turn off" genes:
Operon
Inducer
Promoter
Repressor
Corepressor
A mutation in this section of DNA could influence the binding of RNA polymerase to the DNA:
(a)
The lactose operon is likely to be transcribed when
there is more glucose in the cell than lactose.
the cyclic AMP levels are low.
there is glucose but no lactose in the cell.
the cyclic AMP and lactose levels are both high within the cell.
the cAMP level is high and the lactose level is low.
How does active CAP induce expression of the genes of the lactose operon?
It terminates production of repressor molecules.
It degrades the substrate allolactose.
It stimulates splicing of the encoded genes.
It stimulates the binding of RNA polymerase to the promoter.
Muscle cells differ from nerve cells mainly because they
express different genes.
contain different genes.
use different genetic codes.
have unique ribosomes
The protein that performs RNA splicing by removing introns and connecting exons is called a(n) (a) .
Which of the following is characteristic of the product of the p53 gene?
It is an activator for other genes.
It speeds up the cell cycle.
It causes cell death via apoptosis.
It allows cells to pass on mutations due to DNA damage.
It slows down the rate of DNA replication by interfering with the binding of DNA polymerase.
The cancer-causing forms of the Ras protein are involved in which of the following processes?
Relaying a signal from a growth factor receptor
DNA replication
DNA repair
Cell cycle control system
Attachment of ______ groups to ______ will cause promotion of gene expression due to looser DNA.
acetyl, DNA
methyl, DNA
acetyl, histones
methyl, histones
The noncoding sequence of DNA located within the promoter where RNA polymerase will bind is called the (a) .
A type of control element that acts with transcription factors to promote initiation may be perceived as a distal control element. This control element is called a(n):
(a)
All of the following occur before mature RNA is formed except:
Addition of a poly-A tail
Addition of a 3' cap
Addition of a release factor
Removal of introns
Alternative splicing
The sequence of nucleotides complementary to one located on mRNA that is carried by tRNA towards the translation site is called a(n):
(a)
Proteins targeted for degradation are tagged with (a) before they are recognized by proteasomes.
The function of siRNAs is to:
play a role in RNAi
contribute to euchromatin formation
degrade mature RNA
contribute to forming mutations in the promoter sequence
Cancerous genes that have undergone some type of transformation from their normal counterparts through mutations are called (a) .
The protein that functions in unwinding DNA strands before replication occurs is called:
Topoisomerase
Single-strand binding proteins
Helicase
Ligase
Spliceosome
The mitotic division undergone by only prokaryotes, such as bacteria is known as (a) .
A type of hereditary pattern exhibited by the coat colors of Labrador retrievers shows a phenotypic ratio of 9:7. This type of pattern is known as:
Polygenetic inheritance
Multiple alleles
Codominance
Incomplete dominance
Epistasis
