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CSIR NET MCQs : DNA Replication

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Ciprofloxacin is a synthetic chemotherapeutic antibiotic of the Flouroquinolone drug class. The target of antibiotic Ciprofloxacin is...

a)

Replication

b)

Membrane Structure

c)

Protein SynthesisCell wall synthesis

d)

Cell wall synthesis

2.

Among the following which is termed as proof reading activity of DNA polymerase?

a)

3->5' Exonuclease activity

b)

5->3' Polymerase activity

c)

3->5' Polymerase activit

d)

5->3' Exonuclease activity

3.

In prokaryotes during replication, the lagging strand synthesized in a series of short fragments known as Okazaki fragments, consequently requiring many primers. The RNA primers of okazaki fragments are subsequently degraded by DNA polymerase I and the gap once the primer have been removed from lagging strand?

a)

DNA from leading strand serves as primer

b)

End of existing Okazaki fragments on lagging strand serves as primer

c)

DNA polymerase I has its own primer

d)

DNA polymerase I do not require primer

4.

Genome of Virus is made up of.....

a)

Proteins

b)

DNA or RNA

c)

DNA

d)

RNA

5.

Most Plant Viruses Contain.....

a)

RNA

b)

DNA

c)

DNA & RNA

d)

None of these

6.

DNA which is the sear of all the hereditary characters is chiefly found in.....

a)

None of these

b)

Nucleus

c)

Chloroplast

d)

Mitochondria

7.

Who demonstrates that DNA replicates in a semi-conservative manner?

a)

Jacob and Monad

b)

Meselson and Stahl

c)

McLeod and McCarty

d)

Watson and Crick

8.

Formation of new DNA molecules from the parent DNA which are exactly similar to its replica is called ...

a)

Gene mutation

b)

Replication of DNA

c)

Segmentation of DNA

d)

Terminalization of DNA

9.

The Two polynucleotide chains of the parent DNA molecule separate due to breaking of.....

a)

O-bond

b)

All of these

c)

S-bond

d)

H-bond

10.

When does the replication of DNA take place?

a)

During mitosis

b)

During pachytene and diplotene of meiosis

c)

During interphase between two mitotic cycles

d)

During meiosis

11.

Which of the following statement /statements is/are correct regarding replication of DNA?

a)

Replication starts at a specific point called origin

b)

Replication is a semi-conservative process in which each of the two double helices formed from the parent double strand have one old and one new strand

c)

Two strands of double helix of DNA unwind with the help of a DNA unwinding protein which binds to single DNA strands.

d)

All of the statements are correct

12.

Who demonstrated by auto-radiography that both chromatids during prophase have half old and half new material?

a)

McLeod and McCarty

b)

Taylor et al

c)

Watson and Crick

d)

Jacob and Monad

13.

Replication may proceed.....

a)

In only one direction (unidirectional)

b)

In both direction (bidirectional)

c)

Can not be determined

d)

None of these

14.

Which of the following enzymes are used to join bits of DNA?

a)

DNA Ligase

b)

Primase

c)

Endonuclease

d)

DNA Polymerase III

15.

Semi conservative replication of DNA was first demonstrated in.....

a)

Salmonella typhimurium

b)

Escherichia coli

c)

Drosophila melanogaster

d)

Streptococcus pneumoniae