WorksheetsOXALIPLATINE
Total questions: 10
Worksheet time: 5mins
What is the study design of the trial comparing the combination of capecitabine and oxaliplatin (CAPOX) with the combination of 5-fluorouracil, leucovorin and oxaliplatin (modified FOLFOX6) as adjuvant therapy in patients with operated high-risk stage II or stage III colorectal cancer.
Double blind Phase III Trial
Multicenter, Randomized Phase III TRial
Randomized Controlled Phase II Trial
What are the 2 Protocols used as adjuvant therapy in patients with operated high-risk stage II or stage III colorectal cancer
CAPOX/ FOLFOX
CARBO/ PACLITAXEL
CAPOX/ FOLFIRI
How many patients erolled in CAPOX/ FOLFOX study?
406
407
408
409
Is the primary End point of the study CAPOX/ FOLFOX?
DFS
OS
PFS
What is the result of the Study CAPOX/FOLFOX ?
NO significant differences were observed in the efficacy of FOLFOX versus CAPOX as adjuvant treatment in high-risk stage II or stage III CRC patients
YES significant differences were observed in the efficacy of FOLFOX versus CAPOX as adjuvant treatment in high-risk stage II or stage III CRC patients
Colorectal cancer is the 2nd Leading cause of cancer death in western countries.
TRUE
FALSE
What is the standard adjuvant treatment of colon cancer?
Fluorouracil
Leucovoorin
Fluorouracil + Leucovorin (FL)
How many patients enrolled in the mosaic Trial?
2,246
1,123
2,456
Primary end point of the Mosaic Trial?
OS
DFS
SAFETY (including longterm AE)
Sinong mas maganda?
Jenny
Ninian
All of the above
