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WorksheetsSulphonamides and nitrofuran
Total questions: 10
Worksheet time: 7mins
Prontosil red in-vivo converted into
Sulphanilamide
2,4-diamino aniline
Both
None of the above
Pyrimidine ring containing sulphonamide examples
Sulphadiazine
Sulfamerazine
Sulphacetamide
Sulphathiazole
Co-trimoxazole is combination of
Sulphadiazine + Trimethoprim
Sulphamethazine + Trimethoprim
Sulphamerazine + Trimethoprim
Sulphamethoxazole + Trimethoprim
N-1 position of sulphonamide substituted with
Thiazole
Pyrazole
Pyridine
Pyrimidine
All of the above
Physicochemical properties required for special pharmaceutical formulation achieved by
Substitution of acyl group at N-1
Substitution of acyl group at N-4
Substitution of aryl group at N-1
Substitution of alkyl group at N-1
Replacement of one H-atom of NH2 by electron withdrawing substitution
(a)
Sulfonamides inhibits
Dihydrofolate synthase
Dihydropterine Pyrophosphokinase
Dihydrofolate reductase
None of the above
Adverse reaction associated with Sulfonamides are
GI disturbances
Crystalluria
Nephrotoxicity
Ototoxicity
Which one is not a Nitrofuran derivative
Nitrofurantoin
Metranidazole
Methenamine
Nitrofurtimox
Nitrofuran derivatives inhibits function
(a)
