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Genetic Engineering Class test

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Restriction enzymes were first discovered in E.coli restricting the replication of ...................., by cutting the DNA

a)

Yeast

b)

Bacteriophages

c)

E.coli

d)

lambda

2.

•DNA ligase joins (seals) the DNA fragments by forming a .......................... bond between the phosphate group of 5′-carbon of one deoxyribose with the hydroxyl group 3′-carbon of another deoxyribose

a)

Phosphodiester

b)

Hydrogen

c)

Weak

d)

all the above

3.

Alkaline phosphatase is an enzyme involved in the ...................phosphate groups.

a)

addition of

b)

removal of

c)

both addition and removal

d)

none of the above

4.

pBR322 is ................base pairs in length

a)

4356

b)

4359

c)

4361

d)

4369

5.

Identify the vector

a)

pBR 322

b)

PUC18

c)

Cosmid

d)

phagemid

6.

........................library is made by cloning DNA made in vitro by reverse transcription of all the mRNA produced by a particular cell

a)

Genomic

b)

cDNA

c)

Both

d)

none of the above

7.

A clone carrying the gene of interest can be identified with a ....................... having a sequence complementary to the gene

a)

primer

b)

isotopes

c)

lacZ

d)

nucleic acid probe

8.

Northern blotting technique was developed by

a)

Neal Burnette

b)

Towbin's group

c)

James alwin

d)

George Stark's group

9.

Who is the father of biotechnology?

a)
b)
c)
d)
10.

Identify the technique

a)

Southern Blotting

b)

Northern Blotting

c)

Western Blotting

d)

Insitu Hybridization