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Diabetes 2

Total questions: 28

Worksheet time: 14mins

Name
Class
Date
1.

What does in utero exposure to hyperglycemia lead

to?

a)

increase fetal fat cells

b)

fetal hyperinsulinemia

c)

insulin resistance in adolescence

d)

all of the above

2.

A 34 year old woman was diagnosed with diabetes at the age of 20. Her initial prenatal care labs return with a 24-hr urine protein of 250mg. She has benign retinopathy on ophthalmologic exam. What White classification does her pregnancy carry?

a)

C

b)

D

c)

F

d)

R

3.

Which of the following findings are considered diagnostic for overt diabetes in pregnancy?

a)

hemoglobin A1C >6%

b)

glucosuria on urine dip

c)

fasting plasma glucose > or equal to 120mg/dL

d)

random plasma glucose > or equal to 200mg/dL

4.

Fetuses of overtly diabetic mothers have an increased risk for which of the following?

a)

preterm delivery

b)

spontaneous abortion

c)

congenital malformation

d)

all of the above

5.

How does diminished fetal growth occur in pregestational diabetes?

a)

substrate deprivation

b)

fetal hyperinsulinemia

c)

altered lipid metabolism

d)

all of the above

6.

Compared to women without diabetes, which fetal condition occurs more often in the setting of pregestational diabetes?

a)

stillbirth

b)

perinatal death

c)

postpartum hemorrhage

d)

gestational hypertension

7.

Which of the following are considered reasons for unexplained fetal demise in women requiring insulin during pregnancy?

a)

nonketotic acidosis

b)

elevated lactic acid levels

c)

decreased fetal hematocrit

d)

none of the above

8.

Which of the following is a reasonable explanation for hydramnios in a pregnancy complicated by diabetes?

a)

maternal endothelial leak caused by hyperglycemia

b)

glucose reabsorption by the fetal glomerular collecting system

c)

osmotic gradient created by high glucose concentrations in the amniotic fluid

d)

all of the above

9.

What is the most likely cause for the increased incidence of respiratory distress syndrome in the neonates of diabetic mothers?

a)

indicated preterm delivery

b)

delayed maturation of type II pneumocytes

c)

decreased production of surfactant in a hyperglycemic environment

d)

all of the above

10.

Which of the following statements regarding cardiomyopathy in infants of diabetic mothers is true?

a)

is reversible after birth

b)

ventricular hypertrophy is due to insulin excess

c)

in severe cases may lead to pulmonary hypertension

d)

in the first trimester systolic dysfunction is already present

11.

All except which of the following statements

regarding hypocalcemia in the newborn is accurate?

a)

Defined as <9 mg/dL

b)

Etiology is unexplained

c)

May be related to preterm birth

d)

Seen more often with strict glucose control

12.

Maternal mortality in women with type 1 diabetes results from which of the following?

a)

infection

b)

hypertension

c)

diabetic ketoacidosis

d)

all of the above

13.

The first and most common visible retinal lesions in diabetes are small micro aneurysms followed by blot hemorrhages. This describes which of the following conditions?

a)

proliferative retinopathy

b)

nonproliferative retinopathy

c)

is irreversible with improved control

d)

the etiology of cotton wool exudates

14.

What is the most important component of diabetic ketoacidosis in pregnancy?

a)

restore euglycemia

b)

provide IV hydration

c)

provide IV potassium repletion

d)

provide IV bicarbonate to correct acidosis

15.

Which of the following infections is increased in pregnant women with overt diabetes?

a)

pyelonephritis

b)

respiratory infections

c)

wound infection after cesarean delivery

d)

all of the above

16.

The most difficult aspect of preconceptional control in women with diabetes is which of the following?

a)

resistance to insulin therapy

b)

unpredictable insulin requirements

c)

half of pregnancies in the US are unplanned

d)

all of the above

17.

Women with type 1 diabetes should achieve glycemic control with which of the following during pregnancy?

a)

insulin

b)

diet alone

c)

insulin and diet

d)

oral hypoglycemic agents

18.

Which of the following is associated with fasting blood glucose levels >120 mg/dL?

a)

preeclampsia

b)

cesarean delivery

c)

birth weight >90th percentile

d)

all of the above

19.

Which of the following is true concerning management of overt maternal diabetes in the second trimester?

a)

should undergo amniocentesis

b)

should undergo a fetal echocardiogram

c)

have higher rates of chromosomal abnormalities

d)

should be offered genetic screening if >35 years of age

20.

ACOG recommends which of the following regarding the management of women with overt diabetes during labor?

a)

morning dose of long acting be held

b)

IV infusion of normal saline

c)

regular IV insulin administered at a rate of 1.25 U/hr if glucose levels exceed 100 mg/dL

d)

all of the above

21.

Concerning screening and diagnosis of gestational DM during pregnancy, which of the following statements is true?

a)

the HAPO study supports the 1-step approach

b)

ACOG recommends a 2-step approach

c)

identifying the 10% of women in the 1-step approach who should not be screened would add unnecessary complexity to the diagnosis of gestational diabetes

d)

all of the above

22.

Which of the following concerning the HAPO study research group are true?

a)

Blood glucoses were measured fasting and then in 2 hours

b)

the reference group for plasma fasting glucose was < or equal to 80 mg/dL

c)

findings supported that increasing plasma glucose levels were associated with increasing adverse outcomes

d)

all of the above

23.

Which of the following factors has been implicated in fetal macrosomia?

a)

leptin

b)

c-peptide

c)

insulin-like growth factor

d)

all of the above

24.

What is the most correct distribution of nutritional intake concerning caloric intake as endorsed by ACOG?

a)

30% fat

b)

30% protein

c)

40% carbohydrates

d)

all of the above

25.

ACOG recommends which of the following concerning exercise in pregnancy for diabetics?

a)

weight lifting is contraindicated

b)

30 min per day of aerobic exercise is recommended

c)

NY Heart Association Class I and II should participate in active aerobic programs

d)

regular physical activity that incorporates aerobic and strength conditioning exercise is recommended during pregnancy

26.

Which of the following statements regarding treatment of gestational DM is accurate?

a)

insulin is the preferred medication in pregnancy

b)

diet and exercise alone should not be used in pregnancy

c)

a trial of oral hypoglycemics can be used prior to initiating insulin therapy

d)

the starting dose of insulin in 0.6-1.0 mg/kg/day in divided doses if insulin is needed

27.

A multigravida with no prenatal care presents to

labor and delivery at 39 weeks' gestation. Her last

baby was born with forceps-assisted vaginal delivery,

weighed 4200 grams, and she had a third-degree

perineal laceration repaired. Her random glucose

is 257 mg/dL and urinalysis reveals 3+ glycosuria.

Bedside ultrasound reveals an estimated fetal weight

of 4634 grams. On exam her cervix is 1 cm dilated.

What course of action do you recommend?

a)

induction of labor

b)

return to clinic in 1 week

c)

amniocentesis for fetal lung maturity

d)

begin insulin and proceed with cesarean delivery

28.

A 29-year-old primigravida with class B diabetes

at 39 weeks' gestation presents to clinic. She has

received parental care throughout pregnancy and her

diabetes is under good control on split dose insulin.

Her fetal anatomy ultrasound and echocardiogram

were normal. The current estimated fetal weight is

4163 grams and her cervix is 1 cm dilated. What

course of action do you recommend?

a)

Cesarean delivery

b)

induction of labor

c)

return to clinic in 1 week

d)

amniocentesis for fetal lung maturity