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Senior Brain Bee Chapter 17: Solving Human Problems

Total questions: 29

Worksheet time: 15mins

Name
Class
Date
1.

What do patients with severe neurological disorder have?

a)

difficulty communicating with the outside world

b)

cerebral palsy

c)

difficulty sleeping

d)

memory loss

2.

What can the Brain Machine Interface do?

a)

it helps people sleep

b)

it causes diseases

c)

it can bypass problems of communicating with the outside world

d)

read glial cells

3.

How can the brain machine interface bypass such problems?

a)

because it runs on electricity

b)

by reading the activity of millions of neurons through

electroencephalographic (EEG) activity from the brain’s surface or from implanted electrodes

c)

because it is big

d)

because it is small

4.

What can a neuroprosthetic device do?

a)

read the activity of neurons

b)

receive signals

c)

detect chemicals

d)

predict the behavioral intentions of research participants

5.

What advantages does the neuroprosthetic device give?

a)

brain machine interface

b)

neural control of parts of their surroundings: from

computer cursors to video games to robotic limbs

c)

big advantages

d)

small advantages

6.

What is the drawback of neuroprosthetic devices?

a)

they can draw information from only a few hundreds of neurons

b)

they break

c)

they are too big

d)

they are robotic

7.

Where are the electrodes surgically embedded in Deep Brain Stimulation?

a)

in the hypothalamus

b)

in specific brain regions

c)

in the cortex

d)

nowhere

8.

How can DBS alleviate specific disease symptoms?

a)

depending on where the electrodes are placed in the brain

b)

because it is small

c)

because it is electric

d)

because it has multiple chemical signalers

9.

What does the implanted device rely on in deep brain stimulation?

a)

electric signals in the neurons

b)

neurotransmitters

c)

action potentials

d)

the fact that neuronal connection uses electrical signals

10.

What does DBS help do?

a)

trigger action potential

b)

attract neurotransmitters

c)

drown out noise and help neurons communicate better

11.

What are some disorders that DBS has been used to treat?

a)

autism

b)

parkinson's

c)

epilepsy, tourette syndrome, and OCD, and dystonia

d)

Phobia and Panic Disorder

12.

What does transcranial stimulation do?

a)

it is the opposite of DBS

b)

Uses magnetic fields or low electric currents to alter neural activity in a specific brain region and indirectly, deeper brain structures to which it connects

c)

uses gravity

d)

uses water molecules

13.

What are the types of transcranial stimulation?

a)

Transcranial magnetic stimulation (TMS)

b)

MRI and PET

c)

Transcranial direct current stimulation

(tDCS)

d)

Transcranial alternating current

stimulation (tACS)

e)

Deep Brain Stimulation

14.

What are some of the applications of DBS?

a)

improving symptoms of all neuronal disorders

b)

curing all genetic disorders

c)

deep brain stimulation

d)

tDCS and tACS might be used to improve working memory as well as to relieve chronic pain

and the symptoms of depression, fibromyalgia, schizophrenia,and other disorders.

15.

What is the problem with Deep Brain Stimulation?

a)

the devices are too powerful for the brain

b)

scientists don't know exactly how these devices work to improve symptoms and they also don't know how to position the devices

c)

the devices are microscopic

d)

the devices are too big

16.

What are stem cells?

a)

neurons

b)

glial cells

c)

all cells

d)

Unspecialized cells that give rise to cells

with specific functions

17.

What can stem cell therapy do?

a)

recycle neurons

b)

create disorders

c)

make glial cells

d)

continuously produce neurons, astrocytes, and oligodendrocytes and replace cells lost to brain diseases

18.

What does Virus mediated therapy do?

a)

Unspecialized cells that give rise to cells

with specific functions

b)

viruses are used to carry therapeutic drugs or genes into the brain to correct nervous system

c)

help neurons

d)

cure disorders

19.

What disease is virus mediated therapy being tested with?

a)

alzheimers

b)

parkinsons

c)

sclerosis

d)

autism spectrum

20.

What do trophic factors control?

a)

harmful chemicals

b)

oxygen and other gases

c)

the development and survival of specific group of neurons

d)

unused chemicals

21.

How can trophic factors improve disease symptoms?

a)

they can cure diseases

b)

they can produce life sustaining chemicals

c)

they can be genetically modified and targeted to a specific brain region where cells have died

d)

they can be engineered

22.

What are some things that Nerve Growth Factor does?

a)

slow down destruction of neurons that use neurotransmitters

b)

prevent cell death

c)

treat Alzheimer's

d)

treat depression

e)

accelerate cell growth

23.

What is one of the biggest challenges in developing new drugs that will help treat neurological or psychiatric diseases?

a)

finding big molecules

b)

finding molecules that can cross the protective blood brain barrier

c)

making huge discoveries

d)

curing the patient

24.

What is the blood brain barrier?

a)

a group of blood cells

b)

a part of the brain

c)

a part of the heart and the roof of the nose

d)

tightly

packed endothelial cells lining blood vessels restrict the kinds of molecules that can enter the

brain.

25.

What is CRISPR-CAS9?

a)

a virus cell

b)

a part of a virus

c)

patterns of DNA sequences found in the genomes of bacteria and other microorganisms

d)

a molecular scissor

26.

What does the CRISPR-CAS9 do when a virus threatens?

a)

the bacteria uses the CRISPR immune system to identify and destroy the viral genome

b)

the immune system responds to the virus

c)

the virus takes over all the cells

d)

the virus consumes the bacteria

27.

Scientists have adapted the CRISPR immune system for animals and now, humans

a)

True

b)

False

28.

What is Cas9?

a)

it is the guide molecule

b)

it is the immune system

c)

it is an enzyme that works like a pair of molecular scissors. A guide molecule is programmed to tell the enzyme exactly where to cut in the DNA.

d)

a neurotransmitter

29.

What is CRISPR-Cas9 technology?

a)

an immune system

b)

a neurotransmitter

c)

it is a viral genome

d)

It is a DNA editing technique, works like a biological

version of a word processing programme’s “find and

replace” button”