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unit test-I

Total questions: 25

Worksheet time: 13mins

Name
Class
Date
1.

The term Bioinformatics was coined by __________.

a)

J.D Watson

b)

Pauline Hogeweg

c)

Margaret Dayhoff

d)

Frederic Sanger

2.

Proteomics refers to the study of __________.

a)

Set of proteins in a specific region of the cell

b)

Biomolecules

c)

Set of proteins

d)

The entire set of expressed proteins in the cell

3.

Homology and similarity tool is called

(a)  

4.

Who is the called the "mother and father of bioinformatics"

a)

David Lipman,

b)

Dayhoff

c)

Hogeweg

d)

Ben

5.

RNA sequencing identifies

a)

Mutation

b)

Protein

c)

Tissue specific gene expression

d)

DNA

6.

Who is the director of the National Center for Biotechnology

a)

Dayhoff

b)

Herbert Boyer

c)

David Lipman,

d)

Paul berg

7.

Name the scientist

a)

Boyer

b)

Paul berg

c)

Mendel

d)

Stanely Cohen

8.

Which tools frameworks for bioinformatics tools and databases have been developed.

a)

ROSETTA

b)

CORBA

c)

FASTA

d)

EMBL

9.

Name the tool which is a text-based format for represent nucleotide sequences or peptide sequences, in which base pairs are represented using single-letter codes.

(a)  

10.

NCBI expand

a)

National Cancer for Biotechnology Information

b)

National Centre for Biotechnology Information

c)

National Cancer for Biology Information

d)

All the above

11.

The genome for E.coli is published in the year

a)

1954

b)

1983

c)

1997

d)

2000

12.

The protein sequence database that provides a high level of integration and also has a very low level of redundancy.

a)

PROSITE

b)

EMBL

c)

SwissProt

d)

GenBank

13.

Tool which is very helpful in providing finer statistical

description of a gene

a)

SGP-1SyntenicGenePrediction

b)

Markovmodels and HMM

c)

GenBank

d)

all the aboe

14.

Define -the application of genomic

approaches and technologies to the identification of drug targets.

a)

Genomics

b)

Cheminformatics

c)

Pharmacogenomics

d)

Proteomics

15.

compares an amino acid query sequence against a protein

sequence database is called

(a)  

16.

compares a nucleotide query sequence against a

nucleotide sequence database is

a)

blastx

b)

tblastn

c)

blastn

d)

blastp

17.

Human genome contains about

a)

2 billion base pairs

b)

3billion base pairs.

c)

1 billion base pairs

d)

none

18.

NCBI stands for

a)

National Centre for Biotechnology

b)

National Column for Biotechnology

c)

National Cancer for Biotechnology

d)

None of the above

19.

Which is the toughest bacteria

a)

Deinococcus radiodurans

b)

Archaeoglobus fulgidus

c)

Thermotoga maritima

d)

Clostridium

20.

a series of overlapping DNA sequences in human genome is

a)

annotation

b)

contigs

c)

fragments

d)

sequences

21.

Laboratory work using chemicals,water,drugs is called

a)

Dry lab

b)

Wet lab

c)

Insilicon lab

d)

web lab

22.

The first complete genome map was published of the bacteria is

a)

Haemophilus influenza

b)

Lactobacillus

c)

Staphylococcus

d)

Enterobacteria

23.

binds to a single-stranded DNA template and synthesizes a complementary strand of DNA the enzyme used is

a)

DNA polymerase

b)

DNA ligase

c)

DNA helicase

d)

none

24.

A continuous stretch of codons that begins with a start codon (usually AUG) and ends at a stop codon is called

a)

Reading frame

b)

Open Reading frame

c)

contigs

d)

all the above

25.

First director of HGP is

a)

Francis Collins

b)

James Watson

c)

Paul Hebberg

d)

None of the above