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Worksheetsunit test-I
Total questions: 25
Worksheet time: 13mins
The term Bioinformatics was coined by __________.
J.D Watson
Pauline Hogeweg
Margaret Dayhoff
Frederic Sanger
Proteomics refers to the study of __________.
Set of proteins in a specific region of the cell
Biomolecules
Set of proteins
The entire set of expressed proteins in the cell
Homology and similarity tool is called
(a)
Who is the called the "mother and father of bioinformatics"
David Lipman,
Dayhoff
Hogeweg
Ben
RNA sequencing identifies
Mutation
Protein
Tissue specific gene expression
DNA
Who is the director of the National Center for Biotechnology
Dayhoff
Herbert Boyer
David Lipman,
Paul berg
Name the scientist
Boyer
Paul berg
Mendel
Stanely Cohen
Which tools frameworks for bioinformatics tools and databases have been developed.
ROSETTA
CORBA
FASTA
EMBL
Name the tool which is a text-based format for represent nucleotide sequences or peptide sequences, in which base pairs are represented using single-letter codes.
(a)
NCBI expand
National Cancer for Biotechnology Information
National Centre for Biotechnology Information
National Cancer for Biology Information
All the above
The genome for E.coli is published in the year
1954
1983
1997
2000
The protein sequence database that provides a high level of integration and also has a very low level of redundancy.
PROSITE
EMBL
SwissProt
GenBank
Tool which is very helpful in providing finer statistical
description of a gene
SGP-1SyntenicGenePrediction
Markovmodels and HMM
GenBank
all the aboe
Define -the application of genomic
approaches and technologies to the identification of drug targets.
Genomics
Cheminformatics
Pharmacogenomics
Proteomics
compares an amino acid query sequence against a protein
sequence database is called
(a)
compares a nucleotide query sequence against a
nucleotide sequence database is
blastx
tblastn
blastn
blastp
Human genome contains about
2 billion base pairs
3billion base pairs.
1 billion base pairs
none
NCBI stands for
National Centre for Biotechnology
National Column for Biotechnology
National Cancer for Biotechnology
None of the above
Which is the toughest bacteria
Deinococcus radiodurans
Archaeoglobus fulgidus
Thermotoga maritima
Clostridium
a series of overlapping DNA sequences in human genome is
annotation
contigs
fragments
sequences
Laboratory work using chemicals,water,drugs is called
Dry lab
Wet lab
Insilicon lab
web lab
The first complete genome map was published of the bacteria is
Haemophilus influenza
Lactobacillus
Staphylococcus
Enterobacteria
binds to a single-stranded DNA template and synthesizes a complementary strand of DNA the enzyme used is
DNA polymerase
DNA ligase
DNA helicase
none
A continuous stretch of codons that begins with a start codon (usually AUG) and ends at a stop codon is called
Reading frame
Open Reading frame
contigs
all the above
First director of HGP is
Francis Collins
James Watson
Paul Hebberg
None of the above
