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synthetic strategies

Total questions: 10

Worksheet time: 18mins

Name
Class
Date
1.

Which of the following statements best describes retrosynthesis?

a)

The reaction conditions required to convert the product of a reaction back to the original starting materials

b)

A strategy used to design a synthesis of a target molecule by working back from the target to simple starting materials

c)

he design of a synthetic scheme using cheap, traditional reagents, rather than expensive modern reagents

d)

The design of reaction conditions such that an equilibrium reaction is pushed towards the products rather than the starting materials.

2.

Which of the following statements best describes a disconnection in retrosynthesis?

a)

A disconnection involves a theoretical disconnection of a bond in a target structure in order to identify simpler structures that could be linked through the formation of that bond

b)

A disconnection involves identifying stages where a bond is split in the corresponding synthesis.

c)

A disconnection identifies retrosynthetic stages which would not be feasible in the corresponding synthesis

d)

A disconnection describes the reaction conditions required to split a target structure into simpler molecules.

3.

Which of the following synthons is an example of Umpulong ?

a)
b)
c)
d)
4.

Which of the synthons (A-D) represents the following reagent?

a)
b)
c)
d)
5.

Which reaction would result in a structure having a cyclohexene such as the following as a molecular signature?

(a)  

6.

describe a synthon?

(a)  

7.

what is regioselectivity

(a)  

8.

The extra carbon in salbutamol prevents

(a)  

9.

In diels alder reaction which of the following is major product

a)

exo

b)

endo

10.

which of the following is a cyclisation reaction

a)

Michael addition

b)

robinson annelation