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Epidemiology Research Design

Total questions: 13

Worksheet time: 21mins

Name
Class
Date
1.

Relative risk is the statistic used with

a)

case control studies

b)

prospective cohort studies

c)

retrospective cohort studies

d)

both prospective and retrospective cohort studies

e)

cross sectional studies

2.

British investigators conducted a study to compare measles-mumps-rubella (MMR) vaccine history among 1,294 children with pervasive development disorder (Autism and Asperger's syndrome) and 4, 469 children without such disorders. (They found no association.) This is an example of which type(s) of study? (This question has two answers. You must select both answers to get the grade).

a)

Experimental

b)

Observational

c)

Cohort

d)

Case-control

e)

Clinical trial

3.

In a hypothetical study, an investigator wants to look at the association between exposure to lead in old homes built in 1940s and the development of autism. The investigator selects a large group of new-born babies who live in old homes built in 1940s and follow them over 10 years to determine who develops autism. Out of the 636 babies exposed to lead, 138 develop autism (a) and 498 do not develop autism (b). Out of 1980 babies not exposed to lead, only 1806 are autism-free after ten years (d) but 174 developed autism (c). Calculate the Relative Risk (RR) value. (Round the answer and write two numbers after the decimal point).

(a)  

4.

Study Type: An epidemiologist records whether each study participant is exposed or not, and then tracks them to see if they develop the disease

a)

Case control

b)

Cohort

c)

Cross sectional

d)

Ecological

5.

Odds ratio is the statistic used with

a)

case control studies

b)

prospective cohort studies

c)

retrospective cohort studies

d)

cross sectional studies

6.

Study type: An investigator divides the patients into two groups, then exposes one group to the pathogen/drug he is testing, and not the other, and looks for development of disease or relief from disease in both groups

a)

cohort

b)

case control

c)

controlled trial

d)

cross sectional

7.

A cohort study differs from a case-control study in that:

a)

subjects are enrolled or categorized on the basis of their exposure status in a cohort study but not in a case-control study

b)

subjects are asked about their exposure status in a cohort study but not in a case-control study

c)

cohort studies require many years to conduct, but case-control studies do not

d)

cohort studies are conducted to investigate chronic diseases, case-control studies are used for infectious diseases

8.

Study type: A group of people from a population is enrolled and their exposure and health outcomes are measured simultaneously at one point in time.

a)

cohort

b)

case control

c)

controlled trial

d)

cross-sectional

9.

Case-control studies use what measure of association?

a)

Absolute Risk Difference

b)

Hazard Ratio

c)

Odds Ratio

d)

Relative Risk

10.

Which studies use historical data? (This question has two answers. You must select both answers to get the grade).

a)

Case-Control

b)

Prospective Cohort

c)

Retrospective Cohort

d)

Prospective case-control

11.

In a hypothetical study, 400 obese individuals were compared to 400 non-obese individuals regarding their consumption of fresh and steamed vegetables each day. In the Obese group, 190 reported eating vegetables each day (c) and 210 reported not eating vegetables (a). In the Non-obese group, 270 reported eating vegetables each day (d) and 130 reported not eating vegetables (b). Calculate the Odds Ratio value using the formula a/c divided by b/d (Round the answer and write two numbers after the decimal point)

(a)  

12.

Study type: An investigator starts by enrolling a group of people with a disease, then finds a matching group without the disease, and then compares their exposures

a)

case control

b)

cohort

c)

cross-sectional

d)

experimental trial

13.

The Iowa Women's Health Study, in which researchers enrolled 41,837 women in 1986 and collected exposure and lifestyle information to assess the relationship between these factors and subsequent occurrence of cancer, is an example of which type(s) of study? (This question has two answers. You must select both to get the grade)

a)

Experimental

b)

Observational

c)

Cohort

d)

Case-Control

e)

Clinical Trial