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WorksheetsGCMB213
Total questions: 20
Worksheet time: 20mins
Which of the following is NOT the step of mRNA processing?
5’ capping
Splicing of introns
Polyadenylation
RNA silencing
Which of the following form 5’cap?
5’ ——> 5’ PPP linkage
5’ ——> 3’ PPP linkage
3’ ——> 3’ PPP linkage
3’ ——> 5’ NPP linkage
Which is the INCORRECT statement about 5’ cap.
Recognized by the transport protein
Provide stability to RNA
Participate in the translation initiation
Increase the life span of RNA
Which of the following group of introns form stable lariat structure?
Group I intron
Group II intron
Nuclear intron
Group III intron
Name the type of intron which needs spliceosomes to be spliced?
Group I intron
Group IV intron
Nuclear intron
Group II intron
Which of the following is not involved in the post transcriptional processing of t-RNA?
a) Base modulation
b) Attachment of CCA arm
c) Splicing
d) Attachment of poly-A tail
What is the main function of t-RNA?
Proof reading
Inhibits protein synthesis
Identifies amino acids and transport them to ribosomes
None of the mentioned
The largest class of introns which are found in nuclear mRNA primary transcript is?
Spliceosomal introns
Group I introns
Group II introns
Group IV introns
Which one of the following best describes the cap modification of eukaryotic mRNA?
Modified guanine nucleotide added to the 3’ end of the transcript
Modified guanine nucleotide added to the 5’ end of the transcript
String of adenine nucleotides added to the 3’ end of the transcript
String of adenine nucleotides added to the 5’ end of the transcript
The basket like structure of filaments in NPC has _________ filaments and is located in ____________ side of the nuclear membrane.
6, nuclear
8, nuclear
6, cytosolic
8, cytosolic
The interaction of importin with Ran.GTP _____________________ its affinity for NLS.
Increases
Decreases
Remains same
They never interact
Nuclear export sequence is _______________ rich.
Lysine
Leucine
FG
RGD
Which of these interactions are weak?
Ran.GTP-exportin-cargo
Ran.GTP-NTF2
Ran.GDP-importin
Ran-GTP-importin
The stem of the hairpin loop of RNA consists mostly of _____________
A, T
G, C
A, G
C, T
The rho protein has ____________ subunit.
4
6
8
10
Mark the statement which is INCORRECT about the transcription unit?
It is a transcribed segment of DNA
Eukaryotes have monocistronic transcription unit
Prokaryotes also have a monocistronic transcription unit
Immediate product of transcription is primary transcript
Name the site where upstream sequences located?
Prior to start point
After the startpoint
Right border of DNA
In the middle of DNA
Who discovered RNA polymerase?
Nirenberg
Watson and Crick
Samuel B. Weiss
Darwin
Which of the following is used to describe the time taken by RNA polymerase to leave the promoter?
Promoter clearance time
Abortive initiation
Elongation factor
Mean time
Mark the one, which is NOT the transcription inhibitor in eukaryotes.
Rifampicin
Acridine dye
Actinomycin D
Rho factor
