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Worksheets

MMG 15-16

Total questions: 27

Worksheet time: 27mins

Name
Class
Date
1.

What is the difference between triglyceride and triacylglycerol?

a)

Triglyceride is what we called "lipid" but triacylglycerol is just a compound made of three glycerol.

b)

Triglyceride is made of three glycerides but triacylglycerol is made of three fatty acid chains.

c)

Triglyceride contains ester linkages of the three fatty acid chains but not in triacylglycerol.

d)

Triacylglycerol contains ester linkages of the three fatty acid chains but not in triglyceride.

e)

None. They are referring to the same compound.

2.

Which of the following about cholesterol is correct?

a)

It is composed of 3 fused carbon rings.

b)

It is the precursor of all steroid hormones.

c)

It can be modified by enzymes to become estradiol in ovary, but not aldosterone and cortisol in adrenal cortex.

d)

It can be modified by enzymes to become aldosterone and cortisol in adrenal cortex, but not estradiol in ovary .

e)

Synthesis of cholesterol involves Malonyl-CoA.

3.

How do we classify fatty acids?

a)

base on their melting points

b)

base on their boiling points

c)

base on their ester linkages

d)

base on the length of their hydrocarbon chains

e)

base on the presence of carbon-carbon double bonds

4.

Consumption of coconut oil may increase the risk for heart diseases. One of the reason is that

a)

most factories manufacturing the coconut oil are unsanitized

b)

the length of the major component, Lauric acid in coconut oil is too long

c)

the major component, Lauric acids are saturated fatty acids

d)

the major component, Lauric acids contain a high proportion of C-C double bond

e)

the major component, Lauric acids are proved to increase risk for prostate cancer

5.

What are the key precursors of synthesizing triacylglycerol?

a)

Glucose

b)

Glyceraldehyde-3-phosphate

c)

Glycerol-3-phosphate

d)

Acetyl CoA

e)

Fatty acyl CoA

6.

Fatty acyl CoA is converted from ? , catalyzed by ?

a)

Fatty acid

b)

Glycerol

c)

Acetyl CoA

d)

cytosolic fatty Acyl CoA synthase

e)

cytosolic fatty Acyl CoA synthetase

7.

Arrange the compounds in order of the synthesis of triacylglycerols. What is the third one?

a)

Phosphatidic acid (DAG phosphate)

b)

Diacylglycerol

c)

Triacylglycerol

d)

Glycerol-3-phosphate

e)

Lysophosphatidic acid

8.

How many fatty acyl CoA is required to produce one triacylglycerol, along with one glycerol phosphate, acyltransferase and phosphatase?

a)

1

b)

2

c)

3

d)

4

e)

5

9.

Triacylglycerol is composed of three fatty acids, regardless of whether they are saturated.

a)

True

b)

False

10.

Regarding the storage of fatty acids and triacylglycerols, which of the following is correct?

a)

Fatty acids are only stored in adipocytes.

b)

Triacylglycerol is only stored in adipocytes.

c)

Adipocytes are not only active in synthesizing, but also hydrolyzing triacylglycerol.

d)

Triacylglycerols are stored in liver in the form of cytosolic oil droplets.

e)

Only the adipocytes in the abdominal cavity are active.

11.

Which of the following steps can be carried out by adipocytes?

a)

Triacylglycerol-->Diacylglycerol

b)

Diacylglycerol-->Monoacylglycerol

c)

Monoacylglycerol-->Glycerol

d)

Glycerol-->Glycerol phosphate

e)

Glycerol phosphate-->Dihydroxyacetone phosphate

12.

Name one hormone that activates the lipase activity.

4 lines
13.

Name one hormone that inhibits the lipase activity.

4 lines
14.

I am made of one sphingosine, one fatty acid and one disaccharide. Who am I?

a)

Neutral glycolipid

b)

Globoside

c)

Ganglioside

d)

A antigen

e)

O antigen

15.

I am made of a sphingosine, a fatty acid, and a polar head group Glu-Gal-Sialic acid. Who am I?

a)

GM 3

b)

GM 2

c)

GM 1

d)

GM 0

e)

GM 9

16.

What sugar distinguishes A antigen from B antigen and O antigen?

a)

Glucose

b)

Galactose

c)

An extra galactose

d)

N-Acetylglucosamine

e)

N-Acetylgalactosamine

17.

Cholera toxin secreted by vibrio cholerae is binded tightly to which receptor in intestinal mucosal cells?

a)

Lactosylceramide

b)

Glucosylcerebroside

c)

GM 3

d)

GM 2

e)

GM 1

18.

Which of the following regarding phosphatidylserine is correct?

a)

PS is a type of glycoprotein.

b)

Each PS is composed of one sphingosine, one fatty acid, and one serine.

c)

PS facing outward are recognized by lymphocytes for removal.

d)

PS is located on the inner leaflet membrane of red blood cell.

e)

PS is diffused into the plasma when there is a need for red blood cell clearance.

19.

Phospholipids are sphingolipids.

a)

True

b)

False

20.

Which of the following about pulmonary surfactants in fetal lungs is correct?

a)

The surfactants are mainly used prevent alveolar collapse within the amnion.

b)

Surfactants are composed of lipoprotein and sphingomyelin.

c)

L/S ratio remains less than 1 before the 30th week.

d)

L/S ratio greater than two indicates possible respiratory distress syndrome.

e)

L/S ratio starts to fall after the 35th week.

21.

What can be used to treat infant RDS? (Hint: It stimulates the production of lecithin before delivery)

a)

Cortisol

b)

Lecithin

c)

Sphingomyelin

d)

Glycoproteins

e)

Glucocorticoid

22.

Arrange the events in phosphatidyl-inositol 4,5 bisphosphate pathway. What is the third step?

a)

Protein kinase C phosphorylates its target proteins.

b)

PIP2 is cleaved into IP3 and DAG by phospholipase C.

c)

IP3 induces ER Ca2+ release to activate protein kinase C; DAG activates PKC directly.

d)

PIP2 is normally present in the plasma membrane.

23.

Major types of eicosanoids are:

a)

Prostacyclins (with cyclic structure)

b)

Prostaglandins (without cyclic structure)

c)

Prostaglandins (with cyclic structure)

d)

Thromboxanes (with cyclic structure)

e)

Leukotrienes (without cyclic structure)

24.

During inflammation, histamine or cytokine activates phospholipase A2, which catalyzes the cleavage off arachidonic acids. Which of the following is the correct match of the pathway and its products?

a)

Prostacyclins (Lipoxygenase pathway)

b)

Leukotrienes (Lipoxygenase pathway)

c)

Prostaglandins (Cyclooxygenase pathway)

d)

Thromboxanes (Cyclooxygenase pathway)

25.

Which anti-inflammatory drug can inhibit both cyclooxygenase pathway and lipoxygenase pathway of arachidonic acid?

a)

Cortisol

b)

Aspirin

c)

Paracetamol

d)

Ibuprofen

e)

Indomethacin

26.

Which of the following about PAF is correct?

a)

PAF is derived from phosphatidylcholine, with an acetyl ester attached to C3.

b)

PAF increases platelet aggregation and mediates hypersensitivity.

c)

PAF synthesis is triggered by phospholipase A2.

d)

IgG on mast cells trigger the activation of PAF.

e)

IgA on mast cells trigger the activation of phospholipase A2.

27.

Which of the following statement is correct?

a)

PGF2α vasodilates blood vessels and inhibits platelet aggregation.

b)

PGI2 from vascular endothelium vasodilates blood vessels and inhibits platelet aggregation.

c)

PGI2 from macrophages vasodilates blood vessels and stimulates platelet aggregation.

d)

PGE2 vasoconstricts blood vessels and stimulates platelet aggregation.

e)

TXA2 vasoconstricts blood vessels and inhibits platelet aggregation.

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