WorksheetsImmune mediated diseases
Total questions: 10
Worksheet time: 10mins
An ulcerated lesion was excised from the lower gingival mucosa of a 45 year-old woman. The histopathological examination showed acantholytic epithelial cells and Tzank cells with accompanying chronic inflammatory cells within the connective tissue. The diagnosis made was …
recurrent aphthous ulcer
herpetic gingivostomatitis
mucous membrane pemphigoid
pemphigus vulgaris
erythema multiforme
The immune system defends the body against foreign substances that are called
plasma cells
antigens
antibody
lymphocytes
A 30 year-old female came with erythematous rashes of butterfly configuration over her malar region and
white striae on her bilateral buccal mucosa. She also complaints of joint pain.
The MOST likely diagnosis is...
erythema multiforme
systemic lupus erythematosus
pemphigus
oral lichen planus
Nikolsky's sign is positive in ...
mucous membrane pemphigoid
steven johnson syndrome
pemphigus vulgaris
oral lichen planus
A 39 year old lady complaint of burning sensation all over her mouth. On examination, extensive mucosal ulceration seen on buccal mucosa and gingiva. Biopsy result showed clefting at basal layer as observed in the figure.
leukoedema
mucous membrane pemphigoid
oral lichen planus
pemphigus
A discontinuation of epithelium is referred to as/an...
erosion
ulcer
attrition
vesicle
A 15 year-old boy complained of painful ulcers and haemorrhagic ulcers on his lips. He reported occurence of similar incident 2 years ago along with oral, skin and genital lesions. It was suggested that a herpetic infection had triggered the lesions.
pemphigus
mucous membrane pemphigoid
sarcoidosis
erythema multiforme
A 47 year old lady complained of painful lesions on the buccal mucosa and burning sensation when eating hot and spicy food. Biopsy was taken from the buccal mucosa showed acantholysis and intraepithelial split.
The condition above MOST likely is...
erosive oral lichen planus
pempigus vulgaris
lupus erythematosus
mucous membrane pemphigoid
Choose the histopathological features of oral lichen planus
Subepithelial band of eosinophils
Presence of parakeratinized stratified squamous epithelium
civatte bodies may be seen
subepithelial band of lymphocytes
Liquefaction degeneration of the stratum granulosum layer
Direct immunofluorescence of lichen
planus shows a…
linear patchy pattern in stratum granulosum with extensions
towards stratum basale
linear pattern outlining the basement membrane with irregular
extensions into the superficial lamina propria
Saw tooth apperance of the parakeratinized epithelium
Fish net appearance seen intraepithelial
