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Chromosomal Abnormalities

Total questions: 20

Worksheet time: 18mins

Name
Class
Date
1.

A procedure that displays the pairs of chromosomes in a cell is called a ____.

a)

genotype

b)

phenotype

c)

karyotype

d)

linotype

e)

chromotype

2.

Nondisjunction can occur if ____ chromosomes fail to separate during meiosis I.

a)

homologous

b)

heterozygous

c)

sex

d)

autosomal

3.

The most common autosomal trisomy at birth is ____.

a)

cri du chat syndrome

b)

Patau syndrom

c)

Klinefelter syndrom

d)

Down syndrome

e)

Turner Syndrom

4.

Persons with Down syndrome typically have how many copies of chromosome 21?

a)

none

b)

one

c)

two

d)

three

5.

Down syndrome may be detected by ____.

a)

a karyotype from chorionic villi testing

b)

a karyotype from anmiocentesis

c)

a test to detect substances in the maternal blood

d)

all of these

6.

Examples of chromosomal mutations are ____ (select all that apply)

a)

inversion

b)

translocation

c)

deletion

d)

duplication

7.

If a segment of a chromosome is present several times more than normal due to unequal crossing-over, it is called ____.

a)

an inversion.

b)

a translocation.

c)

a delection.

d)

a duplication.

8.

If a segment of a chromosome is turned around 180 degrees, it results in ____.

a)

an inversion.

b)

a translocation.

c)

a delection.

d)

a duplication.

9.

A Barr body is a condensed, inactive X chromosome.

a)

True

b)

False

10.

A person with Turner syndrome has ____ sex chromosome(s).

a)

zero

b)

one

c)

two

d)

three

11.

An egg or ovum has a(n) ____ chromosome.

a)

X

b)

Y

c)

either X or Y

d)

extra X or Y

12.

An sperm has a(n) ____ chromosome.

a)

X

b)

Y

c)

either X or Y

d)

extra X or Y

13.

The sex of a newborn child is determined by the ____.

a)

mother

b)

father

c)

both mother and father

14.

Nondisjunction during spermatogenesis can lead to a sperm with _____. (select all that apply)

a)

no sex chromosome

b)

an X and a Y chromosome

c)

two X chromosomes

d)

two Y chromosomes

15.

A person with Turner syndrome has the following sex chromosomes(s).

a)

X

b)

Y

c)

both X and Y

d)

neither X nor Y

16.

A person with Klinefelter syndrome _____.

a)

is a sterile male

b)

is a sterile female

c)

can be either a sterile male or female

d)

in neutral and neither male nor female

17.

Nondisjunction during oogenesis can lead to an egg with _____. (select all that apply)

a)

two X chromosomes

b)

no X chromosomes

18.

Normally, an individual receives _____ autosomes from each parent.

a)

2

b)

22

c)

44

d)

46

19.

Normally, an individual receives two sex chromosomes from a parent.

a)

True

b)

False

20.

Nondisjunction results in an uneven distribution of chromosomes during cell replication. If nondisjunction occurs during meiosis I, the homologous chromosomes do not separate. If nondisjunction happens in meiosis II, sister chromatids do not separate. If a cell has a diploid number of six (2N = 6) before meiosis, how many chromosomes will be in each of the four daughter cells if one pair of chromosomes experiences nondisjunction during meiosis I?

a)

Two cells will have 6 chromosomes, two cells will have none.

b)

Two cells will have 4 chromosomes, two cells will have 2 chromosomes.

c)

Two cells will have 5 chromosomes, two cells will have 1 chromosome.

d)

All four cells will have 3 chromosomes.