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WorksheetsREVISION CHAPTER 7 & 8
Total questions: 20
Worksheet time: 12mins
Notice the abnormal 23rd chromosome. This individual suffers from which chromosomal genetic disorder?
Klinefelter Syndrome
Down Syndrome
Cri-du-Chat Syndrome
Andrew Syndrome
Chromosomal number alterations refer to __________.
Changes in structure of chromosome
Changes in sequence of bases in DNA
Changes in numbers of chromosomes
Changes in numbers of organisms
A person with Cri-du-Chat Syndrome is
missing chromosome # 5
trisomy 13
trisomy 21
missing part of chromosome # 5
Another name for trisomy 21 is
Patau Syndrome
Down syndrome
Edward syndrome
Turner syndrome
Klinefelter Syndrome is caused by the presence of
an extra Y-chromosome (XYY)
an extra X-chromosome (XXY)
a missing X-chromosome ( _X)
trisomy 21
Plant A (2n=10) mates with plant B (2n=12) produce a sterile hybrid which evolved to a fertile hybrid. What is the chromosome number of a fertile hybrid?
33
44
11
22
Which of the following terms describes the process of the uptake of recombinant plasmids into bacteria cells?
amplification
insertion
transformation
screening
The cell that able to receive recombinant DNA for cloning purpose known as
vector
target DNA
plasmid
host cell
To produce desired protein _____________ should be taken from any source like human, animal and plant.
recombinant DNA
Target DNA
plasmid
ligase
Arrange a correct sequence of process in production of cDNA.
I. Reverse transcriptase used to synthesis single stranded cDNA complementary to mRNA
II. Remove mRNA
III. Extract mRNA from cell
IV. Use DNA polymerase to synthesis second stranded cDNA
I, II, III, IV
III, IV, II, 1
III, I, II, IV
II, III, I, IV
Which of the characteristic is NOT belong to host cell
Able to accept recombinant DNA
Able to accept target DNA
Able to maintain structure of recombinat DNA
Able to express the gene of interest
Which gene is used as selectable marker in a plasmid?
Ampicillin resistance gene
Plasmid resistance gene
Salmonella resistance gene
Penicillin resistance gene
Which of the following is a correct sequence of process in recombinant DNA technology?
I. Isolation of target DNA & vector
II. Introducing recombinant DNA into host cell
III. Fragmentation of target DNA & vector by restriction endonuclease
IV. Ligation of DNA fragment into vector Culturing in host cell to get desired products.
I, II, III, IV
I, III, IV, II
I, II, IV, III
I, IV, II, III
