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Qilu Palonosetron Hydrochloride Injection

Total questions: 10

Worksheet time: 2hrs 40mins

Name
Class
Date
1.

What is the strength of Qilu Palonosetron per 5 ml?

a)

2.5 mg

b)

25 mg

c)

25 mcg

d)

250 mcg

2.

Qilu Palonosetron belongs to which pharmacological group of antiemetic?

a)

5-HT3 antagonist

b)

Neurokinin-1 antagonist

c)

Dopamine antagonist

d)

Benzodiazepine

3.

Which of the following is NOT the indication of Qilu Palonosetron?

a)

Chemotherapy-induced nausea and vomiting (CINV)

b)

Prevention of CINV associated with HEC

c)

Prevention of CINV associated with MEC

d)

Prevention of CINV associated with LEC

4.

Which of the following cytotoxic agent is NOT a moderately emetogenic chemotherapy?

a)

Oxaliplatin

b)

Carboplatin

c)

Cisplatin

d)

Irinotecan

5.

Which of the following are the complications of CINV?

a)

Dehydration & electrolyte imbalance

b)

Poor quality of life & unable to perform normal daily activities

c)

Refusal to continue chemotherapy

d)

Physical & mental deterioration

6.

Which of the following was withdrawn by the FDA because of the possibility of life-threatening cardiac arrhythmias due to QT-interval prolongation?

a)

Domperidone

b)

Granisetron

c)

Dolasetron

d)

Ondansetron

7.

Choose the most accurate timeline of 5-HT3 antagonist injection being approved by FDA from the earliest to latest.

a)

Palonosetron, Granisetron, Ondansetron, Dolasetron

b)

Ondansetron, Granisetron, Dolasetron, Palonosetron

c)

Dolasetron, Granisetron, Ondansetron, Palonosetron

d)

Granisetron, Dolasetron, Ondansetron, Palonosetron

8.

Which of the following regarding to palonosetron is/are correct?

a)

It has the longest half-life among 5-HT3 antagonists

b)

It is usually use alone as antiemetic for HEC

c)

It is a 2nd generation 5-HT3 antagonists

d)

It can be given intravenously and intramuscularly

9.

Which of the following is NOT the benefit of palonosetron?

a)

Longer half-life and stronger binding affinity than the first generation 5-HT3 antagonists

b)

High risk of cardiac QT-interval prolongation

c)

Single dose regime which improves patient compliance

d)

None of the above

10.

Which of the following regarding to the manufacturer is FALSE?

a)

The company was established in 2015

b)

The manufacturing site is in Haikou city, Hainan, China

c)

The company name is Qilu Pharmaceutical (Hainan) Co., Ltd

d)

Palonosetron is their first product registered in Medispec