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Total questions: 25
Worksheet time: 28mins
45 years old women present with weight gain and recurrent dizziness. Over the past 4 months she has gained 20kg weight and "dizziness" episode occur on daily basis with blurring of vision, sweating, headaches nd palpitation. She went to KK and blood sugar record 1.4 mmol/L and it was persistently low even after correction. What is the single most useful test?
Thyroid function test
Glucagon Stimulation test
C Peptide
Short ACTH test
Cortisol level
32 Years old woman who is at 24 weeks pregnant with her 3rd child come to the clinic for review. she has been diagnosed with gestational diabetes mellitus and a fasting plasma glucose following 2 weeks adherence to lifestyle changes is 6.8mmol/L. Her blood pressure is 122/82mmHg, Her BMI 25. Her sister suffers from diabetic type 1. Which following is the most appropriate treatment
S/c Glargine
Dapaglifozin
Metformin
Glibenclamide
Insulin Pump
52 years old woman in the ED with dyspnea accompanied by nausea and vomiting. She is suffering from DM type 2, hypertension, and obesity. Her current medication is metformin 1g bd, canagliflozin 100 mg od, ramipril 10 mg od and amlodipine 10 mg od. On examination RR 25 breath per min, and O2 saturation is 98% under room air. Other examination is unremarkable except she has epigastric tenderness. Blood result as per attachment. What is the most likely diagnosis?
small bowel obstruction
Metformin induce Lactic acidosis
Starvation ketosis
Euglycemic diabetic ketoacidosis
Pancreatitis
20years old man presents with a nine months history weight gain. Prior to this, he was of normal weight. On examination of his, BMI is 36, BP 150/90, he is noted to have abdominal striae and some degree of myopathy. Blood investigation as per attachment. what is the next best investigation?
Plasma ACTH
24 Hour urine cortisol
Renal:Aldosterone ratio
thyroid fucntion test
Insulin growth factor
23 years old man with severe Chron's disease has been put on complete bowel rest for an indefinite period of time whilst he in-patient recovery. he received total parenteral nutrition for past few weeks. recently his skin become dry and scaly with mouth ulcers and lip swelling. what cause of this changes
Cheilitis
Extra bowel manifestation of Chrons
folliculitis
Palisaded neutrophilic and granulomatous dermatitis
Acrodermatitis herpetiform
64 years old man present with severe mucosal ulceration associated with the development of blistering lesions over his torso and arm. On examination, the blisters are flaccid and easily ruptured when touched. What is the most likely diagnosis?
Pemphigoid
Dermatitis herpetiformis
Psoriasis
Pemphigus Vulgaris
Epidermolysis bullosa
43 years old man has schizophrenia with interspersed with periods of depression. Presented with above skin lesion. What is the most likely drug cause this skin lesion?
sodium valproate
quetiapine
valproic acid
fluoxetine
lithium
28 years old man who has recently emigrated from Thailand presents with a penile ulcer. It initially started as papule which later progressed to become painful ulcer with an undermined ragged edge. Examination of the testes was unremarkable but tender inguinal lymphadenopathy was noted. What is the most likely diagnosis?
Chancroid
Lymphogranuloma Venerum
Syphilis
Herpes Simplex
Granuloma inguinale
35 years old man was diagnosed with HIV and is stable on antiretroviral therapy. He has a new regular partner and is concern about transmission of the disease to him. What is the factor is most likely to increase the risk of transmission?
Circumcision
Low CD4 Count
Genital warts
Diabetes
Mucosal ulceration
A 38 years old woman presents to the clinic with a history of hypertension since 10 years ago. Currently, she is on amlodipine and ramipril. On examination, the heart rate is 80 bpm, and blood pressure is 180/110mmHg. What is the most likely cause of her hypertension?
Bartter Syndrome
Bilateral renal artery stenosis
Gitelman syndrome
Primary hyperaldosteronism
Acromegaly
35 years old woman presents with a one-week history of progressive leg swelling. Her past medical history includes DM type 2. On examination, there is bilateral pedal edema up to knee and peri orbital dedema. Her HR is 88/min, BP 151/95mmHg, Temperature 37C. Urine dipstick showed protein 4+. Two days later, she complains of hematuria and left-sided pain. Her renal profile deranges to stage 1 AKI. What is the most likely diagnosis?
Hemorrhagic Cyst
Urinary tract infection
Renal vein thrombosis
Ureteric calculi
Hemolysis
70 years old man admitted with abdominal pain. The surgeons wish to perform contrast-enhanced Ct Scan but he concerns about his chronic kidney disease stage 3b. Which the following is the best step to prevent contrast-induced nephropathy?
Oral sodium bicarb
N acetylcysteine
Intravenous 0.9% sodium chloride
Frusemide
Mannitol
68 years old man presents with painful swollen left knee which failed to settle after a week rest. there is no history of trauma. On examination, he has a moderate-sized effusion. the plain radiograph was done. What is the most likely diagnosis?
Pseudogout
Rheumatoid arthritis
Sarcoidosis
Psoarisis athropathy
Osteoarthritis
27 years old woman presents with genital ulceration. She had recurrent similar attacks for the past 4 years. Oral aciclovir has some little effect on the duration of her symptoms. She notices for the past year almost weekly she had mouth ulcers which recently slow to heal. Her only past medical problem, she had been warded for thrombophlebitis. What is the most likely diagnosis?
Polyarthritis Nodosa
Systemic Lupus Erythromatous
Bachet Disease
Herpes Simplex Virus
Syphilis
64 years old man presents with 8 months history of generalised weakness. On examination, he has fasciculation and weakness in both arms with absent reflexes and the lower limb reveal increased tone and exaggerated reflexes. The sensation is intact and there no cerebellar signs. what is the most likely diagnosis?
Progressive muscular dysthrophy
Amyothrophic lateral sclerosis
Multiple sclerosis
Vitamin B 12 dificiency
Syringomyelia
A 30 years old lady presents with the acute occipital headache associated with vomiting, photophobia and neck stiffness. There is no history of rash or fever. She reported had a history of young hypertensionwhihc lead to pheochromocytoma diagnosis and surgical resection was done and currently, she is not on antihypertensive medication. Her father died due to kidney cancer and the brother is blind on the right eye due to bleed in the eye. What is the most likely diagnosis?
Autosomal dominant polycyctic kidney disease
Multiple endocrine neoplasia type 1
Von Hipple Lindau disease
Tuberous sclerosis
Alport Syndrome
62 years old man is admitted to the emergency department with left hemiplegia. His symptoms started around 5 and half hours, but he initially thought he had slept in a backwards position. He has no past medical history of not but on examination is found to have an irregular pulse of 100 bpm. The ECG confirms atrial fibrillation. A CT head reported as normal. What is the most appropriate initial management?
Dabigatran
Dipyridamole
Alteplase
Warfarin
Aspirin
62 year old man presents with letraghy. A full blood count is taken and reported
hb 10.2g/dL
platlet 330
WBC 15.2
Peripheral blood film as per picture. What is the most likely diagnosis?
Myelodysplasia
Chronic lymphocytic leukaemia
Myelofibrosis
Chronic myeloid leukemia
Post-splenectomy
34 years old female presents with a purpuric rash on the back of her calf. She also reported frequent nose bleeds and menorrhagia. Currently, she took OCP to regulate her menses. A full blood count reveals as per picture. What is the most likely diagnosis?
Idiiopathic thrombocytopenic purpura
Henoch-Schonlein purpura
Thrombotc thrombocytopenic purpura
Drug induce thrombocytopenia
Antiphospholipid syndrome
79 years old man is admitted with right lower lobe pneumonia. As well as showing consolidation there is a moderated pleural effusion on the same side. An ultrasound-guided pleural tapping was done. The appearance of the fluid is clear and is sent off for investigation and culture & sensitivity. Which is the following is the most important factor in the pleural fluid to determine the insertion of a chest tube for this gentleman?
Glucose
Type of microorganism
LDH
pH
Protein
45 years old lady presented to the chest clinic with a history of persistent cough and dyspnea. The cough is associated with an amount large of sputum and sometimes difficult to cough it out. Her family has coal business, her father and brother have a similar problem thus make her think this is a common problem. She married for 20 years and no children. What is the most likely diagnosis?
Cystic fibrosis
Coal pneumoconiosis
COPD
Kartagener's syndrome
Sjogren syndrome
59 years old woman presents with dysphagia. There is no history of heartburn, weight loss or change in bowel habit. during endoscopy, there is some difficulty passing through the lower esophageal sphincter but no other abnormality is noted. which one of the following test is most likely to reveal the diagnosis?
Esophageal biopsy
Endoscopy ultrasound
CT abdomen
Esophageal manometry
Chest Xray
30 years old woman is admitted to hospital with abdominal pain and diarrhoea. She has no past medical history other than depression for which she takes citalopram. She smokes 20 cigarettes per day and drinks 20 unit of alcohol per weeks. Endoscopy show features cobblestone appearances. Besides glucocorticoid treatment, what is the best way to present recurrence or relapse of the disease?
infliximab
oral Budesonide
Stop Smoking
Mesalazine
Stop Alcohol
34 years gentleman is investigated for frequent syncopal attack and recently he had an episode of collapse whilst at work. A resting ECG showed convex St elevation of V1-V3 with partial right bundle branch block pattern. What is the most likely diagnosis?
Polymorphic vantricular tachycardia
Hypertrophic obstructive cardiomyopathy
ST elevation Myocardiac infarction
Brugada syndrome
Normal variant ECG
65 years old man known case of ischemic heart disease, hypertension, chronic kidney disease stage 2 and diabetes mellitus. His medication is Amlodipine, Losartan, Metformin, Gliclazide, Aspirin, Vasteral and Bisoprolol. Recently he was been admitted for compensated heart failure. On examination, his BP 160/90, HR 78, Lung examination is minimal crepitation. His chest x-ray showed borderline cardiomegaly and Hba1c 8.5%. As a physician in charge of him, what is the best medication to be added to prevent recurrence and progression of his disease?
Frusemide
Perindopril
Dapagliflozin
Plavix
Liraglutide
