NEW
Font size
WorksheetsSTC assessment 4
Total questions: 20
Worksheet time: 15mins
Adaptation phase in CRISPR-Cas operates by
Blocking entry of viral nucleic acid
Activating Restriction Enzymes
Integrating a short piece of viral DNA in CRISPR locus
none of the above
For Genome editing a double stranded cut at the target DNA is required
True
False
CRISPR genome editing works both in eukaryotes and prokaryotes
True
False
The nuclease function of Cas9 has to be removed for gene silencing
True
False
Off-target effects are not a concern for CRISPR mediated genome editing
True
False
The binding of CRISPR RNA alone with the incoming viral DNA is sufficient to protect the bacterial cell
True
False
In the context of a data, information and noise are relatively defined terms with respect to the researcher’s perspective. The perspectives change and so do the label.
True
False
Would all modified (Crossover in GA) products be novel?
Yes
No
May be
66% of them will be novel
Started with phrases of one note and three-consecutive-notes the string SagaRe in Indian classical music could be obtained by ________
Mutation
Crossover
Either of them
None of them
AI models could possibly be employed for ________ out of the following 6 applications
a. Identification b. Classification c. Prediction
d. Error correction e. Validation f. Missing data recovery
3
5
6
None of these
Smart devices are the products of Technology _______?
2.0
3.0
4.0
(ii) and (iii)
16S rDNA is the gene of choice for deciphering the composition of microbes in a sample. Why?
conserved at amino acid level
highly divergent
alternating conserved and variable regions
not found in eukaryotes
If the amplicon size is 350 bases and the two paired-end reads from the same amplicon are 200 bases long, the length of the overlap between the paired end reads are
150
100
75
50
N50 is
measure of gene expression
quality of assembly
concentration of DNA
model of sequencing machine
How will you detect mutation that is a potential cause for a rare familial recessive disorder
look for mutation in one arm
look for homozygous alternate allele in both arms
look for heterozygous alternate allele in both arms
none of the above
Bisulfite treatment of DNA results in following changes
all T become C
all methylated C become T
all unmethylated C become T
all A becomes C
Which of these molecular biology platforms has the best resolution?
Karyotyping
Sanger Sequencing
PCR
None of the above
Which of this test is used for detecting chromosomal disorders in fetus?
NIPS
PGS
PGD
Clinical Exome
Which of the following communities is a good example of founder mutation?
The Ashkenazi community
The Bohri Muslim community
The Iyers of Palakkad
The Bhotias of Sikkim
Coding region makes about
10% of the genome
2% of the genome
50% of the genome
100% of the genome
