WorksheetsBiological Explanation of Anorexia
Total questions: 23
Worksheet time: 12mins
Which biological explanation should you write about in your exam?
evolutionary
genetic
hormonal
neuroanatomical
Strober et al conducted a study of first degree relative of people with and without eating disorders. What sort of study was this?
twin study
family/familial study
kinship study
adoption study
According to Strober et al. (2000), eating disorders were ...... in people with a relative with an eating disorder than those without.
11 times
9 times
5 times
15 times
Heritability of anorexia is estimated to be around....
60%
65%
70%
75%
Which gene controls the development of dopamine transporter molecules?
DAT1
COMT
5-HTR2A
EPHX2
DAT1 codes for a protein that creates...
dopamine transporter molecules
dopamine receptors
an enzyme that breaks down dopamine
serotonin receptors
A mutation of the DAT1 gene leads to abnormal dopamine transporter molecules meaning that levels of dopamine in the synapse are...
higher than average
lower than average
High levels of dopamine in the synapse can lead to down regulation of the ....
transporter molecules on the presynaptic cell
receptors on the presynaptic cell
transporter molecules on the postsynaptic cell
receptors on the postsynaptic cell
Down regulation as a consequence of a DAT1 mutation could mean people have...
lower than average dopaminergic activity
higher than average dopaminergic activity
Which of the following is NOT true. Mutation of the DAT1 gene could mean that people develop anorexia due to...
lack pleasure at the thought of food
eating is not a rewarding experience for them
they don't feel hungry
low levels of dopamine due to down regulation of post-synaptic receptors
Dopamaine transporter molecules are on the...
presynaptic cell
postsynaptic cell
DAT1 mutation can lead to abnormal transmission of neural impulses in the....
mesocorticolimbic pathway
hippocampus
cingulate cortex
hypothalamus
The 5HTR2A gene codes for a protein linked to serotonin
transporter molecules
receptors (all of them)
a specific sub-type of receptor called 2A
MAO the enzyme that breaks down serotonin
5HT 2A receptors are found on the
post synaptic cell
pre synaptic cell
Serotonin is ...
an inhibitory neurotransmitter
an excitatory neurotransmitter
Inhibitory neurotransmitters make the post synaptic cell...
less likely to fire an action potential
more likely to fire an action potential
Mutation of the 5HTR2A gene leads to abnormality of the 2a receptors meaning...
neural impulses continue to be fired in this neural network
neural impulses are inhibited in this neural network
Lack of inhibition due to mutation of the 5HTR2A gene could mean that people...
still feel full when they should be getting hungry
feel hungry even when they should be still feeling full
Which of the following brain regions is associated with decreased 5HTR2a activity and is linked to anorexia?
cingulate cortex
nucleus accumbens
mesocorticolimbic pathways
striatum
Treasure and Holland conducted a ....
twin study
family study
adoption study
genome wide association study
In Treasure and Holland the concordance rate for MZ twins was....
65%
32%
40%
12%
In Treasure and Holland the concordance rate for DZ twins was....
65%
32%
40%
12%
Which of the following is a not a strength of the genetic explanation of anorexia...
twin studies evidence e.g. Treasure and Holland
application to the possible development of preventative drug treatments
The equal environments assumption
Kaye's review paper on 5HT2a and anorexia.
