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WorksheetsGene Regulation
Total questions: 36
Worksheet time: 20mins
Name
Class
Date
1.
Most gene regulation happens at which step along the way?
a)
translation
b)
transcription
c)
signal transduction
d)
DNA replication
2.
what does a promoter do?
a)
it allows a gene to be transcribed
b)
it creates a DNA segment
c)
it is another word for ribosomes
d)
it is another word for RNA
3.
A protein that binds to the operator and blocks the RNA polymerase
a)
regulator
b)
repressor
c)
activator
d)
corepressor
4.
In the lac operon model the genes within the operon will be expressed if:
a)
lactose is absent in the cell
b)
glucose is present in the cell
c)
lactose is present in the cell
5.
Why are insertion and deletion mutations so harmful?
a)
They change all of the codons from the mutation on down the line, which changes the amino acid sequence
b)
They insert things that an organism doesn't need.
c)
They often delete things that organisms need.
d)
Insertion and deletions are not any more harmful than substitution mutations.
6.
Identify the SUBSTITUTION mutation from the following DNA sequence:
ATG CCA AAT
ATG CCA AAT
a)
ATG TCA AAT
b)
ATG CCT AAA T
c)
ATC CA AT
d)
ATG CCA AAT
7.
In eukaryotes, proteins that help the RNA polymerase bind to the regulatory region for transcription are called ____________.
a)
transcription factors
b)
topoisomerase
c)
regulatory genes
d)
activators
8.
What is the name given to part of a DNA molecule that codes for a protein?
a)
Glucose
b)
Chromosome
c)
Gene
d)
Phosphate
9.
What does the lactose do to the Operon?
a)
Blocks transcription because of the energy it provides
b)
Allows the repressor to be unbind from the Operator.
c)
The lactose binds the lactose and stops transcription
d)
Allows for the transcription to speed
10.
Which of the following statements regarding mRNA is correct?
a)
Exons are included in the protein sequence, while introns are left out
b)
Introns are included in the protein sequence, while exons are left out
c)
Exons and Introns can both be included or left out depending on the protein
d)
Exons and Introns are both part of the mRNA sequence, but only exons are part of the rRNA and tRNA
11.
How can a person's muscle cells have the same exact DNA sequences as their nerve cells even though the look and perform completely different?
a)
The two different cells become mutated
b)
The proteins expressed in each cell are different
c)
They actually have different DNA in the two types of cells.
d)
The genome of the different cells changes
12.
What is the role of operons in prokaryote gene expression?
a)
It makes the genes prokaryotes be turned on
b)
It accounts for the regulation of gene activity in response to the needs of the cells
c)
To make DNA for the gene
d)
To make the gene turn of and off
13.
What structure of this molecule binds with the mRNA molecule?
a)
Amino Acid
b)
tRNA
c)
Anticodon
d)
Codon
14.
The "on/off" switch for an operon is called the
a)
promoter
b)
repressor
c)
operator
d)
gene
15.
what does a promoter do?
a)
it allows a gene to be transcribed
b)
it creates a DNA segment
c)
it is another word for ribosomes
d)
it is another word for RNA
16.
what is an operon?
a)
a part of a ribsome
b)
a part of a Rna
c)
a unit made up of linked genes that code for proteins needed to do a specific task
d)
needed for dna replication
17.
An operon consists of all the the following EXCEPT
a)
operator
b)
promoter
c)
regulatory gene
d)
genes of the operon
18.
A protein that binds to the operator and blocks the RNA polymerase
a)
regulator
b)
repressor
c)
activator
d)
corepressor
19.
A small molecule that binds to a repressor and makes it active
a)
repressor
b)
regulator
c)
activator
d)
corepressor
20.
A small molecule that binds to the repressor and makes it inactive is
a)
corepressor
b)
inducer
c)
promoter
d)
operator
21.
When a gene transcribes unless turned off by a repressor, it is considered _____ control
a)
negative
b)
positive
22.
When a gene does not transcribe unless turned on by activator , it is considered _____ control
a)
positive
b)
negative
23.
Two types of negative control are
a)
repressible & inducible
b)
repressible & active
c)
active & inactive
d)
repressible & corepressible
24.
Inducible negative control is when when the gene is transcribed by the ____ of a specific molecule
a)
presence
b)
absence
25.
Repressible negative control is when when the gene is transcribed by the ____ of a specific molecule
a)
presence
b)
absence
26.
What is an example of positive control?
a)
The lac operon being transcribed when lactose is present
b)
The trp operon being transcribed when tryptophan is absent
c)
the lac promoter being activated by CAP when cAMP levels rise
d)
control is all just an illusion
27.
All of the following are true about DNA methylation EXCEPT
a)
takes place on the DNA
b)
enzymes add a methyl group
c)
when it occurs, transcription is more likely to occur
d)
chromatin becomes more tightly packed
28.
All of the following are true about histone acetylation EXCEPT
a)
takes place on the histone
b)
enzymes add a acetyl group
c)
when it occurs, transcription is more likely to occur
d)
chromatin becomes more tightly packed
29.
Inheritance of traits by mechanisms not directly involving nucleotide sequence is called
a)
epigenetic inheritance
b)
differential gene expression
c)
chromosomal inheritance
d)
gene regulation
30.
In eukaryotes, a cluster of proteins that assemble on the promoter is called the
a)
transcription initiation complex
b)
control element
c)
activator
d)
protein blobby thing
31.
In eukaryotes, proteins that help the RNA polymerase bind to the promoter for transcription
a)
transcription factors
b)
topoisomerase
c)
regulatory genes
d)
activators
32.
A distal control region that activators bind to are bent to contact mediator proteins and form the transcription initiation complex
a)
enhancers
b)
promoters
c)
repressors
d)
transcription factors
33.
In embryonic development, the process by which cells specialize is called
a)
differentiation
b)
morphogenesis
c)
cell division
d)
endoplasmic reticulum
34.
In embryonic development, the physical process of an organism developing its shape is called
a)
differentiation
b)
morphogenesis
c)
cell division
d)
topoisomerase
35.
differentiation and morphogenesis are controlled by internal transcription factors, proteins and organelles in the cell... this is called
a)
cytoplasmic determinants
b)
inductive signals
c)
endosymbiotic theory
d)
epigenetic inheritance
36.
differentiation and morphogenesis are controlled by external factors, such as contact and signals from neighboring cells... this is called
a)
cytoplasmic determinants
b)
inductive signals
c)
endosymbiotic theory
d)
epigenetic inheritance
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