WorksheetsNeuro P10
Total questions: 8
Worksheet time: 8mins
Cocaine' Mechanisms
Binds to receptors at the cell body in the VTA, it excites the neuron so that it fires more action potentials that move toward the synapse, causing more dopamine release.
Activity of NMDA and AMPA receptors is inhibited, reducing cation entry into the cell.
Blocks dopamine reuptake transporter which cause the dopamine not being able to transport back to the pre-synaptic neurone for degradation by (Monoamine)
Binds to nicotine receptors on the dopamine-containing axon terminals in the nucleus accumbens, more dopamine is released with each action potential.
Consequences of continued addiction
Easily Agitated
Become a easy going person
Loss in decision making
Death
Choose the correct description for Mesolimbic Pathway
It forms extensive connections with the frontal lobes
It transports dopamine from the VTA to the nucleus accumbens, amygdala
It originates from hippocampus
It is an useless pathway
Match the correct neurotransmitters with the correct feeling
Dopamine - Sad
GABA - fear
Norepinephrine - Happy
None of the above
When increased amounts of a drug or behaviour is needed to produce the desired effect, this phenomenon is called
Withdrawal
Psychological dependence
Physiological dependence
Tolerance
Nicotine in cigarette smoke has been found
To increase urinary flow
To increase heartbeat rate and blood pressure
To improve cognitive thinking and learning of a person.
To cause a scarcity of dopamine and drug dependence
Which of the two mentioned are connected by the dopamine reward pathway?
midbrain; frontal cortex
thalamus; hypothalamus
rhombencephalon; diencephalon
midbrain; occipital lobe
How does drug tolerance develop?
The body produces more receptors for the drugs to bind to, reducing the effectiveness of the drug.
The brain has reduced activity, resulting in a need for a higher dose of drug.
The body produces hormones to reduce the effectiveness of the drug.
The liver produces more enzymes, increasing the rate of certain drug metabolism.
