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Higher 2.7 - Genetic Control of Metabolism

Total questions: 18

Worksheet time: 9mins

Name
Class
Date
1.

Which of the following is a consequence of mutagenesis?

a)

Mutations will produce an improved strain of a microorganism

b)

Mutations may produce an improved strain of a microorganism

c)

Mutations do not produce an improved strain of a microorganism

2.

Which process involves exposing microorganisms to mutagenic agents?

a)

Mutagenesis

b)

Recombinant DNA Technology

3.

Which process involves transferring genes from one organism into a microorganism?

a)

Mutagenesis

b)

Recombinant DNA Technology

4.

What term is used to describe a combinant of an organisms original DNA and DNA from another source?

a)

Recombinant DNA

b)

Mutagenesis

c)

Vector

d)

Artificial Chromosomes

5.

Which enzyme cuts the desired gene out of the donor DNA?

a)

Restriction endonuclease

b)

Ligase

c)

DNA Polymerase

d)

RNA Polymerase

6.

Which enzyme cuts the plasmid open?

a)

Restriction endonuclease

b)

Ligase

c)

DNA Polymerase

d)

RNA Polymerase

7.

Which enzyme seals the desired gene into a plasmid?

a)

Restriction endonuclease

b)

Ligase

c)

DNA Polymerase

d)

RNA Polymerase

8.

A restriction site is...

a)

A specific target sequence of DNA bases

b)

A general sequence of DNA bases

c)

The area of a plasmid that is cut open

d)

The mutated strands of DNA during mutagenesis

9.

What is the function of a vector?

a)

A DNA molecule used to carry foreign genetic information to another cell

b)

To cut out a specific target sequence of DNA

c)

To seal a desired gene into a plasmid

d)

To protect the microorganism from a selective agent

10.

Which of the following is not an example of a vector?

a)

Plasmid

b)

Artificial Chromosomes

c)

Restriction endonuclease

11.

Which vector is capable of carrying long DNA sequences?

a)

Plasmid

b)

Artificial Chromosomes

12.

What is the role of an origin of replication?

a)

Initiates the self replication of the vector

b)

The target sequence of DNA cut out by restriction endonuclease

c)

Antibiotic resistance genes that protect the microorganism

d)

Controls gene expression

13.

What is the role of regulatory sequences?

a)

Initiates the self replication of the vector

b)

The target sequence of DNA cut out by restriction endonuclease

c)

Antibiotic resistance genes that protect the microorganism

d)

Controls gene expression

14.

What is the role of selectable markers?

a)

Initiates the self replication of the vector

b)

The target sequence of DNA cut out by restriction endonuclease

c)

Antibiotic resistance genes that protect the microorganism

d)

Controls gene expression

15.

How can a selectable marker be used to tell if the host cell has successfully taken up the vector?

a)

Only microorganisms with the vector survive

b)

Microorganisms with and without the vector survive

c)

Only microorganisms without the vector survive

16.

Which of the following is a safety mechanism in recombinant DNA technology?

a)

Adding genes to prevent survival in an external environment

b)

Only cutting out specific target sequences

c)

Using ligase to seal the desired gene into a plasmid

d)

Using recombinant yeast cells

17.

What happens if the 3D structure of recombinant bacteria proteins are incorrectly folded?

a)

The protein is inactive and does not correctly work

b)

The protein is active and works correctly

18.

Which of the following is used to produce correctly folded, more complicated proteins?

a)

Eukaryotic yeast

b)

Prokaryotic bacteria

c)

Prokaryotic archaea