A patient is taking omeprazole 40 mg by mouth daily for GERD and was started on clopidogrel 75 mg daily and aspirin 81 mg daily for one year s/p NSTEMI and 3 stents. STOP AND USE A DRUG INTERACTION TOOL. Which anti-reflux medicaiton would NOT interact with this patient's clopidogrel? [SELECT ALL THAT APPLY]

A patient attempts a 2 week trial of a PPI; however, they only receive slight relief and feel they need to continue it beyond 2 weeks. You refer them to their primary care provider who refers to GI and the patient is found to have erosive esophagitis on endoscopy. How long should you treat this patient?

What if the patient had non-erosive esophagitis?

Mother of a 3 y.o. wants to use something OTC to help with reflux that her child has been experiencing for the last 3 days. She says the child is complaining that their stomach hurts. The child will sometimes regurgitate some food after breakfast, but is fine the rest of the day. What is an appropriate recommendation to make for this parent?

Patient is having reflux and burning immediately after eating that lasts about 2 hours. Symptoms do not always occur, and will typically occur for 2 days then go away for a few days. Happening 1-2 times per week. Does not associate this with triggers. Besides non-pharm, what recommendation would you make in this patient?

A patient is taking calcium carbonate 750 mg for reflux. They do not feel it is lasting long enough and they state the reflux will come back after about 3 hours in which they need to take the medication again. This is happening about once every week without any noticeable triggers. What would you recommend they do in addition to non-pharm?

A patient who is pregnant and in their 2nd trimester has is having GERD symptoms daily that are getting worse each weak. They have tried antacids and they helped initially, but symptoms are now breaking through. The patient's OB wants to know what medication they should try next. What is an appropriate recommendation?

A 14-year-old who eats late-night snacks complains of nocturnal GERD symptoms for the last 4 nights and is wanting something to help. They refuse to stop their night-time snacks as they are almost done with season 4 of Apex legends and they are trying to improve in rank. As the teenager explains all this to you in a very dramatic way, you notice their father stand behind them with noticeable shadows under his eyes, clearly exhausted from the constant arguments. The father stares blankly at you, and you notice the non-verbal "please help me" in his listless eyes. What is an appropriate recommendation for this patient?

Which adverse effect is associated with long-term PPI use?