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MNP (Quiz 1)

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Marine natural products are small- to medium-

molecular weight compounds produced by...

a)

Marine

plants, invertebrates and microbes

b)

Coastal plant and vertebrates

c)

Marine plant, vertebrates and microbes

d)

Microbes and coastal plant

2.

Why study Marine Natural Product?

a)

Lead us to a fundamental understanding of Drug discovery from the plant

b)

Has a profound impact on our understanding of medicine, health, nutrition and the environment

c)

Interesting topic to the human

d)

Has many benefit to the marine economic global

3.

Steps in New Drug Development

a)

Idea or hypothesis, New drugs discovery, screening, per-clinical studies , formulation, clinical studies and marketing

b)

Idea or hypothesis, formulation, screening, clinical studies and marketing

c)

New drugs discovery, screening, per-clinical studies , formulation, and marketing

d)

Idea or hypothesis, New drugs discovery, formulation, clinical studies and marketing

4.

Since when early societies recognized that the diversity of plant life could be used for the treatment of human illness – natural preparation (tea, salve, etc).

a)

>2000 years ago

b)

<3000 yeas ago

c)

>3000 years ago

d)

Since currently

5.

The first marine drug was Ziconotide, a potent pain medication extracted from...

a)

Venomous gastropod mollusk Conus magus

b)

Marine vertebrate venomous

c)

Microbes associated with sponges

d)

Seaweed

6.

Drug discovery research from marine organisms has been accelerating and now involves interdisciplinary research including...

a)

biochemistry, sociology, and pharmacology.

b)

Biology, ecology, organic chemistry, socioeconomic, and pharmacology.

c)

Biochemistry, organic chemistry, and pharmacology.

d)

Biochemistry, biology, ecology, organic chemistry, and pharmacology.

7.

Examples of Marine Organism-derived Compounds in anti-tumor Clinical Trials

a)

Aplidine, agelasphin, bryostatin I

b)

Amlodipin, statin

c)

Penicilin and aplidine

d)

Bryostatin and penicilin

8.

A potent antitumor agent, was isolated from the marine tunicate Ecteinascidia turbinata.

a)

Esteinascidin and Squalamine

b)

Esteinascidin

c)

Squalamin and amida

d)

Spisulosine and derivates

9.

•Recently, much attention has been given to marine organisms due to their considerable biodiversity that has been found in the widespread oceans that cover....

a)

Over 70% of the world

b)

Over 80% of the world

c)

Over 60% of the world

d)

Over 90% of the world.

10.

What is the name of antibiotic drug that discovery by Alexander Fleming in the late 1920s?

a)

Statin

b)

Penicillin

c)

Amoxicillin

d)

tetracycline