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WSH IB SL 3.1 + 3.2 preview

Total questions: 25

Worksheet time: 12mins

Name
Class
Date
1.

What distinguishes an allele from a gene?

a)

An allele is made of RNA.

b)

An allele is shorter.

c)

An allele is a variety of a gene.

d)

An allele cannot be transferred during genetic modification.

2.

What is the effect of dominant alleles?


I. They mask the effect of recessive alleles.

II. They become more frequent than recessive alleles in a population.

III. They have a joint effect with recessive alleles when characteristics are co-dominant.

a)

I only

b)

I and II only

c)

I and III only

d)

I, II and III

3.

What is the composition of eukaryotic chromosomes?

a)

DNA only

b)

DNA and ribose

c)

DNA and RNA

d)

DNA and proteins

4.

What is the name given to a heritable factor which controls a specific characteristic?

a)

Allele

b)

Chromosome

c)

Gene

d)

Mutation

5.

What is a gene mutation?

a)

Failure of chromosome pairs to separate properly during cell division

b)

Changes to genes caused by natural selection

c)

Changes to the nucleotide sequence of the genetic material

d)

Changes in karyotypes

6.

What is the difference between the alleles of a gene?

a)

Their position on the chromosome

b)

Their amino acid sequence

c)

Their pentose sugars

d)

Their base sequence

7.

Which of the following statements about homologous chromosomes is correct?

a)

Each gene is at the same locus on both chromosomes.

b)

They are two identical copies of a parent chromosome which are attached to one another at the centromere.

c)

They always produce identical phenotypes.

d)

They are chromosomes that have identical genes and alleles.

8.

What are homologous chromosomes?

a)

Identical chromosomes

b)

Non-identical chromosomes with different genes

c)

Non-identical chromosomes with the same genes in the same sequence but not necessarily the same alleles

d)

Non-identical chromosomes with the same genes in a different sequence and not necessarily the same alleles

9.

What is the set of alleles that an individual possesses?

a)

A gene

b)

A genotype

c)

A genome

d)

A genus

10.

What is an individual's genome?

a)

An organism's complete set of genetic information

b)

Only an organism's chromosomes

c)

The average position of each gene for a species

11.

How much of a human's genome is shared with another human

a)

~60%

b)

~99%

c)

~75%

d)

~90%

12.

Where do somatic mutations occur?

a)

In the cells of the body

b)

In the germline

13.

What defines a germline mutation?

a)

The gene it affects

b)

The allele it gives rise to

c)

That it might be passed onto offspring

d)

That it causes a biological sex change

14.

Sickle cell anemia may be an example of what when taken in context of malaria?

a)

An exacerbating condition

b)

A heterozygous advantage

c)

It has no effect

d)

No direct connection, but exacerbates

15.

Which of the following are examples of substitution mutations? Check all that apply

a)

Silent

b)

Missense

c)

Nonsense

d)

Insertions

e)

Deletions

16.

Which of the following are examples of frameshift mutations? Check all that apply

a)

Silent

b)

Missense

c)

Nonsense

d)

Insertions

e)

Deletions

17.

What term would you use to describe the location of a gene on a chromosome?

a)

Allele

b)

Sequence

c)

Locus

d)

Site

18.

What is the molecular action of sickle cell anemia?

a)

The alteration of hemoglobin

b)

The production of insoluble fibers

c)

Crosslinking of the cell membrane

d)

Substitution of iron core of hemoglobin

19.

How many chromosomes does a human have?

a)

23

b)

46

c)

44

d)

22

20.

How many chromosomes does a haploid cell have?

a)

2n

b)

n

c)

4n

d)

1/2n

21.

How could you tell that a karyotype was potentially taken from a biological male human? (referring only to biological sex)

a)

Staining for the SRY gene

b)

PCR of the SRY gene

c)

The presence of a Y chromosome

d)

The absence of a second X chromosome

22.

What's a plasmid?

a)

A circular construct of DNA found in all cells

b)

A circular construct of DNA found in prokaryotes only

c)

A circular construct of DNA found in mitochondria

d)

A circular construct of DNA found in eukaryotes only

23.

You would be able to identify a patient with Down's syndrome with a karyogram by:

a)

Half the number of chromosome 21

b)

An extra 21st chromosome

c)

A complete absence of the 21st chromosome

d)

4 complete 21st chromosomes

24.

What are two symptoms of sickle cell anemia?

a)

Fatigue

b)

Blood clotting

c)

Excessive bleeding

d)

Difficulty breathing

25.

An autosome is:

a)

Any chromosome that is not a sex chromosome

b)

All chromosomes passed onto offspring

c)

A specialized type of sex chromosome

d)

The arrangement of chromatin found in gametes