WorksheetsMicroS3LQ1 Recall
Total questions: 30
Worksheet time: 15mins
Glycoprotein projections on the surface of enveloped viruses are called _____
capsomeres
peplomers
protomers
nucleocapsid
Which of the following is TRUE of viruses?
Viruses evolved from bacteria
Viruses infect humans only
Viruses contain both DNA and RNA as their genome
Viruses replicate only in living cells and are inert in the extracellular environment
Which of the following viruses exhibit complex symmetry?
Adenovirus
Herpesvirus
Poxvirus
Parvovirus
Which of the following is an enveloped virus?
Adenovirus
Parvovirus
Herpesvirus
Reovirus
Which of the following is NOT a function of viral proteins?
Facilitate transfer of the viral nucleic acid from one host cell to another
Protect the viral genome against inactivation by nucleases
Participate in the attachment of the virus particle to a susceptible cell
Renders the viruses susceptible to the action of ether and other organic solvents
Capsomeres are _____
virus-encoded glycoproteins exposed on the surface of the virus envelope
morphologic units found on the surface of icosahedral virus particles and represent clusters of polypeptides
membranes made of lipid that surrounds some virus particles
protein–nucleic acid complex representing the packaged form of the viral genome
Which of the following types of cell culture for cultivation of viruses are made by dispersing cells from freshly removed host tissues and are unable to grow for more than a few passages in culture?
Primary cultures
Secondary cultures
Diploid cell lines
Continuous cell lines
Which of the following agents can inactivate viruses?
Quaternary ammonium compounds
Organic iodide compounds
Broad spectrum antibiotics
Ultraviolet rays
These structures are produced during viral multiplication within cells, which can become larger than the virus particle and often have affinity for acid dyes; they may be situated in the nucleus, the cytoplasm, or both, and they are the site of development of virions in many viral infections:
nucleocapsid
inclusion bodies
peplomers
hemagglutinin
Which of the following can be used to distinguish viruses that possess an envelope from those that do not?
growth on diploid cell lines
chlorine susceptibility
Ether susceptibility
stabilization by salts
The following is not included in the process of Herpes simplex primary infection?
virus must encounter broken mucosal surfaces
transmitted through respiratory droplets and sexual contact
viral replication does not occur at the site of infection
virus is transported to the dorsal root ganglia
The following statement is true?
Herpes simplex type 1 and type 2 are exclusively restricted to cause infection in the mucous membrane above the waist and below the waist respectively
Initial HSV-2 infection tends to be less severe in person with immunity to HSV-1
Neonatal herpes can only be acquired during delivery
Herpes simplex 2 is not likely to cause CNS infection
John has been exposed to his classmate with chickenpox. Since he was not able to received varicella vaccine yet, the following may happen to John?
vesicular lesions may start to appear after 10-21 days
the skin lesions are all externally located sparing the buccal and pharyngeal mucosa
vesicular lesions appear in 5 days time
the skin lesions are generally painful
Grandfather Joe suddenly develops vesicular crops of lesions on his face. The following may not be true regarding the zoster infection?
it is associated with post herpetic neuralgia
Zoster occurs in the presence of varicella neutralizing antibody
antibodies produced by varicella vaccine that may last for 20 years prevents zoster infection
Cellular immunity and interferon are important in the recovery
A newborn baby was suspected to have cytomegalovirus (CMV) infection. The following symptom is not likely to be present in the baby with CMV infection?
intrauterine growth retardation
retinitis
hepatosplenomegaly
cataract
The diagnostic test that would immediately identify the presence of CMV from urine is?
viral isolation
PCR
serology
An autistic boy was admitted due to fever which was associated with sore throat, cervical lymphadenopathies, jaundice and splenomegaly. CBC revealed lymphocytosis with some atypical lymphocytes on peripheral blood smear. PCR revealed Epstein Barr Virus. The most likely diagnosis is?
Carcinoma
Blood Dyscrasia
Infectious Mononucelosis
Dengue Fever
The following serological test denotes current infection with Infectious Mononucleosis?
VCA IgG
VCA IgM
EBNA IgG
An HIV volunteer during a feeding program should refrain from being exposed to this particular virus to prevent from developing a vascular tumor?
Epstein Barr Virus
Herpes Simplex Virus
Human Herpes Virus 8
Human Herpes Virus 6
The following virus is not known to establish latent infection in the glands, lymphoid tissue and kidneys?
Herpes Simplex
Cytomegalovirus
EBV
Human Herpes virus 8
What is the viral replication cycle which entails physical separation of the viral nucleic acid from the outer components of the virion?
Adsorption
Penetration
Uncoating
Synthesis
What is the viral replication phase which involves transcription of specific mRNAs for viral nucleic acid?
Penetration
Synthesis
Assembly
Release
In which phase of the viral replication cycle will newly formed viral genome organize together to form progeny viruses?
Adsorption
Synthesis
Assembly
Release
Cytopathic effects may develop as a result of an invading virus. Which of these may be seen as a cytopathic effect?
Cell necrosis
Cytoplasmic vacuolation
Giant cell formation
All of the above
What is the procedure done to detect the presence of infectious viral particles?
Neutralization test
Plaque assay
Polymerase chain reaction
Hemagglutination-inhibition test
The entire replication process of poxviruses takes place in the cytoplasm of infected cells
T
F
Poxviruses can undergo the process of nongenetic reactivation.
T
F
The variola virus is the agent used for smallpox vaccination.
T
F
Re-infections with smallpox virus made it difficult to eradicate the infection.
T
F
Molluscum contagiosum has been reported to occur in humans only
T
F
