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Infectious Diseases Quiz I

Total questions: 14

Worksheet time: 7mins

Name
Class
Date
1.

Antibodies specific to coronavirus that causes COVID-19 were transferred to unborn babies of women who had been infected by COVID-19 during pregnancy. This is an example of artificial passive immunity.

a)

True

b)

False

2.

Innate immune response is targeted towards a specific group of pathogens.

a)

True

b)

False

3.

Pathogens engulfed by macrophages are degraded by enzymes present in the cytoplasm of the macrophage.

a)

True

b)

False

4.

Antigen presenting cells (APC) present antigens on MHC class I to naïve CD4 T cells and B cells.

a)

True

b)

False

5.

B cell maturation occurs in the blood whereas T cell maturation occurs in the trachea.

a)

True

b)

False

6.

One of the signals required for the activation of naive CD4 T cells is the binding of CD28 protein on CD4 T cells with CD80 protein on the APC.

a)

True

b)

False

7.

Cytotoxic-T cells release granzymes and perforin to kill cells infected by pathogen.

a)

True

b)

False

8.

During B cell clonal selection and expansion, cells with a very high affinity for the antigen will divide and differentiate into plasma cells.

a)

True

b)

False

9.

Antibodies are glycoproteins with a tertiary structure.

a)

True

b)

False

10.

The B cell receptors of a B cell and the antibodies released by that B cell after activation recognise different antigens.

a)

True

b)

False

11.

IgG is the first class/type of antibody produced during a humoral response.

a)

True

b)

False

12.

Somatic recombination of the heavy and light chain genes of B cells occurs during mRNA splicing.

a)

True

b)

False

13.

Somatic hypermutation allows antibodies to recognise a wider range of antigens.

a)

True

b)

False

14.

Class switching involves changes made to the DNA segments coding for constant region of the heavy chain.

a)

True

b)

False