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PCR and G/E

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

What does PCR accomplish?

a)

determining the sequence of DNA

b)

develop proteins

c)

make copies of a DNA section

d)

make mRNA

2.

What is the first step of PCR?

a)

termination

b)

denaturation

c)

annealing

d)

splicing

e)

extension

3.

What is the denaturation step?

a)

mutating RNA polymerase

b)

Cooling DNA to allow primers to form

c)

separating DNA helix in a cold environment

d)

separating DNA helix with using heat

4.

At what temperature does the Denature step of PCR occur?

a)

95° C

b)

50° C

c)

72° C

d)

Any temperature

5.

What is the second step of PCR?

a)

denaturation

b)

extension

c)

annealing

d)

termination

e)

splicing

6.

What is the Annealing step?

a)

DNA is cooled to allow primers to form

b)

Heat is used to separate DNA strands

c)

DNA polymerase adds nucleotides to the 5' end

d)

Taq adds nucleotides to the 3' end

7.
What is the function of a primer?
a)
To identify the particular region of DNA to be copied by PCR.
b)
To copy DNA.
c)
To create DNA nucleotides.
d)
To maintain the temperature of the PCR reaction.
8.

At what temperature does the Anneal step of PCR occur?

a)

95° C

b)

50° C

c)

72° C

d)

Any temperature

9.

What is the Extension step?

a)

DNA polymerase adds nucleotides to the 5' end

b)

RNA polymerase adds nucleotides to the 5' end

c)

DNA polymerase adds nucleotides to the 3' end

d)

RNA polymerase adds nucleotides to the 3' end

10.
From where does Taq polymerase come?
a)
Bacteria that live in hydrothermal vents/hot springs.
b)
Cambodia
c)
The rain forest
d)
The CDC
11.

At what temperature does the Extension step of PCR occur?

a)

95°C

b)

50-65°C

c)

72°C

d)

Any temperature

12.
What is the purpose of the Extension step of PCR?
a)
To create the primers.
b)
To extend the time it takes to produce DNA.
c)
To allow polymerase to create the complementary strands of DNA.
d)
To allow substrates to copy DNA sequences.
13.
What is the purpose of gel electrophoresis?
a)
helps cut DNA
b)
count the genes in DNA
c)
separates DNA based on size
d)
allows for an exact replicated organism
14.

A student performed a gel electrophoresis experiment. The results are represented in the diagram

below. Compared to the fragments at the top of the gel, the fragments at the lower end are

a)

larger, and move slower

b)

larger, and move faster

c)

smaller, and move faster

d)

smaller, and move slower

15.
Why do the fragments of DNA in gel electrophoresis travel away from the negative electrode?
a)
DNA is negatively charged so attracted to the positive end of the unit
b)
DNA is positively charged to attracted to the negative end of the unit
c)
the agarose gel in negatively charged
d)
the agarose gel is positively charged