Worksheets模擬考-細菌-真菌-全範圍
Total questions: 80
Worksheet time: 27mins
Name
Class
Date
1.
下列有關細菌transposable elements的敘述,何者錯誤?
a)
傳遞抗藥基因
b)
影響細菌致病力
c)
隨意插入細菌染色體
d)
不能插入細菌質體
2.
糞便培養時,關於致病菌與最佳培養條件之配對,下列何者錯誤?
a)
Shigella boydii–35℃,有氧培養箱
b)
Vibrio cholerae–35℃,有氧培養箱
c)
Campylobacter jejuni–42℃,微需氧培養箱
d)
Clostridium difficile–35℃,有氧培養箱
3.
下列何種細菌為catalase陽性,modified oxidase陽性,且對0.04 U bacitracin具感受性?
a)
Enterococcus spp.
b)
Micrococcus spp.
c)
Staphylococcus spp.
d)
Streptococcus spp.
4.
下列何種培養基無法觀察H2S產生?
a)
Hektoen enteric agar
b)
MacConkey agar
c)
Salmonella Shigella agar
d)
xylose lysine deoxycholate agar
5.
最常見汙染馬鈴薯蛋沙拉,引起胃腸道感染之細菌為何?
a)
Staphylococcus aureus
b)
Bacillus cereus
c)
Vibrio spp.
d)
Candida spp.
6.
院內感染管制中,對於上呼吸道的感染,最常從病人的鼻孔分離出下列何種菌?
a)
Mycobacterium avium complex
b)
Staphylococcus aureus
c)
Vibrio parahaemolyticus
d)
Treponema pallidum
7.
不發酵乳糖的細菌在MacConkey agar上主要呈現的顏色為:
a)
粉紅
b)
橘黃
c)
藍綠
d)
無色
8.
對人體致病的Staphylococcus,會產生凝固酶(coagulase)者是:
a)
Staphylococcus aureus
b)
S. haemolyticus
c)
S. hominis
d)
S. auricularis
9.
Staphylococcus epidermidis可能引起心內膜炎等疾病,下列何者不是其致病有關的因子?
a)
莢膜多醣黏附因子(PS/A, polysaccharide-adhesion)
b)
Extracellular slime substance (ESS, colonization factor)
c)
與血清或組織產生交互作用的能力
d)
凝固因子及Protein A
10.
下列何種試驗不能用於區分Micrococcus及Staphylococcus?
a)
Catalase test
b)
Modified oxidase test
c)
Lysostaphin susceptibility test
d)
Fermentation of glucose
11.
下列何種病原菌,較常由免疫力低下(immunocompromised)的病患血液中分離出?
a)
Corynebacterium jeikeium
b)
Staphylococcus aureus
c)
group A streptococci
d)
E. coli
12.
下列Streptococcus pyogenes毒力因子中,何者之基因位於潛溶噬菌體(lysogenic bacteriophage)上?
a)
Streptococcal pyrogenic exotoxin A and C
b)
Streptococcal pyrogenic exotoxin B and F
c)
M protein
d)
Streptolysin O
13.
Bacillus anthracis之何種組成分或產物,可誘發宿主產生保護性抗體,也是人類疫苗的主要成分?
a)
Capsule
b)
Edema factor
c)
Lethal factor
d)
Protective antigen
14.
下列何種試驗,最能確定臨床分離的Corynebacterium diphtheriae具有產毒力?
a)
Nagler test
b)
inhibitory CAMP test
c)
Ascoli test
d)
Elek test
15.
下列何種細菌特徵為革蘭氏陽性球菌、catalase陰性、生長於綿羊血平板培養基為窄β-溶血環、CAMP試驗陽性?
a)
Enterococcus faecalis
b)
Streptococcus agalactiae
c)
Streptococcus pneumonia
d)
Streptococcus pyogenes
16.
下列何種細菌,在sheep blood agar上形成不溶血菌落,邊緣不規則,有往外生長的長絲狀突起,外觀如medusa head?
a)
Bacillus anthracis
b)
Bacillus cereus
c)
Corynebacterium pseudotuberculosis
d)
Erysipelothrix rhusiopathiae
17.
Streptococcus pyogenes在有氧環境下於BAP表面形成的菌落,其溶血反應主要是下列何種毒力因子造成的?
a)
Streptolysin O
b)
Streptolysin S
c)
Hyaluronidase
d)
Streptokinase
18.
有關臨床常見的Enterococcus spp.特性之敘述,下列何者錯誤?
a)
porphyrin test呈陽性
b)
可在pH 9.6或10~45℃的環境中生長
c)
可耐受高濃度膽汁(bile)並水解esculin
d)
可水解L-pyrrolidonyl-β-naphthylamide
19.
下列何者可以區分Enterococcus與 group A streptococcus?
a)
esculin 水解能力
b)
bile solubilitytest
c)
catalase test
d)
CAMP test
20.
目前臨床上以巢式PCR進行Mycobacterium tuberculosis的檢測,最常用的標靶物(target)為:
a)
pncA
b)
IS6110
c)
mecA
d)
tox1
21.
生長速度最快的Mycobacterium為?
a)
M. tuberculosis
b)
M. avium complex
c)
M. fortuitum
d)
M. kansasii
22.
AIDS患者最常見之分枝桿菌感染為:
a)
Mycobacterium bovis
b)
Mycobacterium marinum
c)
Mycobacterium avium complex
d)
Mycobacterium chelonei
23.
下列何者無法用來區分Bacillus anthracis與Bacillus cereus?
a)
Motility
b)
Lecithinase test
c)
Gelatin hydrolysis
d)
Penicillin susceptibility
24.
下列何種病菌易出現於受感染的牛隻所產生的牛奶中?
a)
Clostridium difficile
b)
Vibrio cholerae
c)
Plesiomonas shigelloides
d)
Mycobacterium bovis
25.
欲避免因棉花拭子含有脂肪酸而造成Neisseria gonorrhoeae死亡,可在攜送培養基中添加下列何種物質?
a)
L-cystine
b)
L-cysteine
c)
Charcoal
d)
Bicarbonate-citric acid
26.
下列何種腸內菌於36℃培養下,呈現陽性運動性試驗(Motility test)反應?
a)
Klebsiella pneumoniae
b)
Enterobacter cloacae
c)
Yersinia enterocolitica
d)
Shigella sonnei
27.
腸內菌在MacConkey agar 上生長,若菌落呈粉紅色則表示該菌有:
a)
lac operon
b)
trp operon
c)
ara operon
d)
flhDC operon
28.
下列何種大腸桿菌之感染會造成Traveler’s diarrhea?
a)
Enterotoxigenic E. coli
b)
Enteropathogenic E. coli
c)
Enterohemorrhagic E. coli
d)
Enteroaggregative E. coli
29.
分離引起出血性腸炎(hemorrhragic colitis)的E. coli O157:H7時最適當的培養基為:
a)
EMB agar
b)
Bismuth sulfite agar
c)
Hectoen agar
d)
Macconkey sorbitol agar
30.
下列何種藥物的感受性試驗可分辨Neisseria cinerea與Neisseria gonorrhoeae?
a)
Colistin
b)
Penicillin
c)
Streptomycin
d)
Tetracycline
31.
Enterobacteriaceae通常具有下列何種特性?(1)ferment glucose (2)catalase-negative (3)oxidase-negative (4)reduce nitrates to nitrites
a)
(1)(2)
b)
(1)(2)(3)
c)
(1)(3)(4)
d)
(1)(2)(3)(4)
32.
在CIN agar培養48小時,會出現bulls eye菌落的是?
a)
Yersinia enterocolitica
b)
Vibrio cholerae
c)
Salmonella typhimurium
d)
Campylobacter jejuni
33.
下列何種細菌的phenylalanine deaminase反應為陽性?
a)
Klebsiella pneumoniae
b)
Morganella morganii
c)
Salmonella typhi
d)
Serratia marcescens
34.
多種方法可提昇從糞便檢體分離Yersinia enterocolitica 之機率,下列何者例外?
a)
使用選擇性培養基 fsulodin-Irgasan-Novobiocin(CIN)agar
b)
接種CCFA agar,置37℃厭氧培養
c)
以PBS(phosphate-buffered saline)冷增菌後,再作次培養
d)
糞便檢體以0.5% KOH (1:2)處理2 分鐘後再作培養
35.
Salmonella sp.有些菌種具有Vi抗原,因而會影響其O抗原與抗血清之凝集,下列何者除外?
a)
Salmonella Typhi
b)
Salmonella Paratyphi C
c)
Salmonella Dublin
d)
Salmonella Typhimurium
36.
下列那一種酵素反應是在滴加了試劑之後10秒鐘就能清楚的觀察到?
a)
Urease
b)
Beta-galactosidase
c)
Cytochrome oxidase
d)
Ornithine decarboxylase
37.
有關Shigella flexneri之敘述,何者正確?
a)
不具運動性
b)
在EMB agar上無法生長
c)
oxidase陽性
d)
對葡萄糖不發酵
38.
下列何者最可能在TSIA上呈現K/A及H2S(+)?
a)
Shigella sonnei
b)
Escherichia coli
c)
Serratia marcescens
d)
Proteus mirabilis
39.
若病人上吐下瀉,排出如米湯樣(rice water)的水樣糞便,則適合用下列何者作為運送兼增菌培養基?
a)
Alkaline peptone water
b)
GN broth
c)
Buffer glycerol saline
d)
Campy-thioglycolate
40.
下列腸內菌中,何者之VP反應為陽性,且不具運動性?
a)
Klebsiella pneumoniae
b)
Enterobacter cloacae
c)
Salmonella typhi
d)
Proteus mirabilis
41.
下列何種細菌的cytochrome oxidase試驗是陰性反應?
a)
Aeromonas hydrophila
b)
Klebsiella pneumoniae
c)
Vibrio cholerae
d)
Vibrio parahaemolyticus
42.
下列有關Gardnerella vaginalis之敘述何者為誤?
a)
oxidase陰性
b)
馬尿酸(hippurate)水解陽性
c)
whiff試驗陽性
d)
對Sodium polyanethol sulfonate(SPS)具抗性
43.
下列何種菌屬於NFGNB (Non-Fermenter Gram Negative Bacilli)
a)
Neisseria gonorrhoeae
b)
Vibrio cholerae
c)
Stenotrophomonas maltophilia
d)
Helicobacter pylori
44.
欲自百日咳患者培養Bordetella pertussis,取何種檢體最適當?
a)
鼻咽部擦拭
b)
直接對瓊脂培養皿咳嗽
c)
痰
d)
血液
45.
下列何種培養基最不適合用於分離Helicobacter pylori?
a)
Blaser’s Campy-BAP
b)
Brucella BAP
c)
BHI-BAP
d)
Modified Thayer-Martin agar(MTM)
46.
下列試驗何者可區分Helicobacter pylori與Campylobacter jejuni?(1)Catalase (2)Oxidase (3)Urease (4)對氧氣之需求 (5)在42℃生長的能力
a)
(1)(3)
b)
(3)(5)
c)
(2)(4)
d)
(1)(5)
47.
有關Burkholderia spp.的運動性試驗結果,下列何者正確?
a)
B. mallei (+),B. pseudomallei (+)
b)
B. mallei (+),B. pseudomallei (-)
c)
B. mallei (-),B. pseudomallei (+)
d)
B. mallei (-),B. pseudomallei (-)
48.
有關Haemophilus之porphyrin試驗之敘述,下列何者正確?
a)
測試細菌是否產生V因子(NAD)
b)
產生紅色螢光為陽性反應
c)
測試細菌是否產生indole
d)
用以鑑別H. haemolyticus和H. influenzae
49.
有關Pseudomonas aeruginosa與Stenotrophomonas maltophilia的oxidase試驗之敘述,下列何者正確?
a)
P. aeruginosa (+),S. maltophilia (+)
b)
P. aeruginosa (+),S. maltophilia (-)
c)
P. aeruginosa (-),S. maltophilia (+)
d)
P. aeruginosa (-),S. maltophilia (-)
50.
下列何者為Hugh and Leifson OF試驗的pH指示劑?
a)
methyl red
b)
phenol red
c)
bromcresol purple
d)
bromthymol blue
51.
有關Legionella spp.形態的敘述,下列何者錯誤?
a)
Short coccobacilli in tissue
b)
Appear pleomorphic on artificial media
c)
Cocci in tissue
d)
Non-spore-forming rod
52.
下列何者不是加護病房中,院內感染常見的病原?
a)
Pseudomonas aeruginosa
b)
Acinetobacter baumannii
c)
Staphylococcus aureus
d)
Streptococcus pyogenes
53.
在 Actinobacillus 屬中,從人分離到最主要的細菌為下列何者?
a)
A. actinomycetemcomitans
b)
A. hominis
c)
A. suis
d)
A. rossii
54.
下列何種細菌具darting motility?
a)
Salmonella spp.
b)
Campylobacter spp.
c)
Proteus spp.
d)
Serratia spp.
55.
培養Ureaplasma urealyticum最適當的pH值為:
a)
2.0~3.0
b)
5.5~6.5
c)
7.0~8.0
d)
8.5~9.5
56.
培養Mycoplasma hominis的培養液常加入下列何種物質,由其是否被利用,可以判斷是否有Mycoplasma hominis生長?
a)
Arginine
b)
Glucose
c)
Urea
d)
Lactose
57.
非特異性血清學檢測肺炎黴漿菌(Mycoplasma pneumoniae)感染之試驗方法為:
a)
Cold agglutination test
b)
Immunofluorescence test
c)
Complement fixation test
d)
Serum neutralization test
58.
有關Bacteroides ureolyticus之敘述,下列何者錯誤?
a)
Catalase陰性
b)
耐vancomycin disk(5 μg)
c)
Nitrate reduction陽性
d)
Urease陰性
59.
厭氧菌在Bacteroides bile esculin(BBE)agar上生長,使培養基呈黑色,其原因為何?
a)
產生H2S
b)
水解esculin
c)
Bile之氧化產物
d)
和bile形成化合物
60.
某革蘭氏陽性厭氧桿菌,菌落呈蜘蛛狀,此菌最可能為下列何者?
a)
Propionibacterium acnes
b)
Actinomyces israelii
c)
Campylobacter gracilis
d)
Bilophila wadsworthia
61.
下列何種試驗最適合區分Prevotella intermedia和Prevotella melaninogenica?
a)
indole
b)
esculin
c)
catalase
d)
H2S
62.
某厭氧革蘭氏陽性桿菌catalase及nitrate reduction反應陽性,不受20% bile抑制,則此菌最可能為下列何者?
a)
Propionibacterium acnes
b)
Actinomyces israelii
c)
Eubacterium limosum
d)
Propionibacterium propionicum
63.
下列何種Clostridium spp. 對氧氣之耐受度最低?
a)
C. difficile
b)
C. haemolyticum
c)
C. perfringens
d)
C. tertium
64.
有關厭氧菌spot indole試驗之敘述,下列何者正確?
a)
比Kovac's indole敏感
b)
比Ehrlich's indole不敏感
c)
陽性反應呈紅色
d)
測試lysine是否轉變為indole
65.
下列何種厭氧菌常引起偽膜性腸炎?
a)
Clostridium botulinum
b)
Clostridium difficile
c)
Clostridium perfringens
d)
Clostridium tetani
66.
請問下列何種細菌於血液培養基中會呈現出雙溶血圈(double zone of hemolysis)特性?
a)
Bacteroides thetaiotaomicron
b)
Fusobacterium necrophorum
c)
Propionibacterium acnes
d)
Clostridium perfringens
67.
感染到下列何者微生物,由於產生神經毒素,會產生角弓反張(opisthotonus)、牙關緊閉(trismus)及痙笑(risus sardonicus)等生理特徵?
a)
Clostridium difficile
b)
Corynebacterium diphtheriae
c)
Clostridium tetani
d)
Bordetella pertussis
68.
下列何種黴菌於培養時需添加脂肪酸才能生長?
a)
Coccidioides immitis
b)
Malassezia furfur
c)
Microsporum canis
d)
Sporothrix schenckii
69.
下列何種酵母菌在適當培養基及溫度下可產生菌絲或假菌絲?
a)
Candida krusei
b)
Rhodotorula sp
c)
Cryptococcus sp.
d)
Candida glabrata
70.
下列何者酵素是Birdseed agar或Caffeic acid disk能產生棕黑色反應的主因?
a)
Elastase
b)
Serine protease
c)
Phenoloxidase
d)
Metalloprotease
71.
下列何種黴菌是汗斑(tinea versicolor)之致病菌?
a)
Exophiala(Phaeoannellomyces)werneckii
b)
Malassezia furfur
c)
Piedra hortae
d)
Trichosporon beigelii
72.
下列何者常造成肺部或全身性感染?
a)
Trichophyton
b)
Microsporum
c)
Histoplasma capsulatum
d)
Epidermophyton
73.
下列何種黴菌可引起athlete’s foot(香港腳)且具urease活性?
a)
Blastomyces dermatitidis
b)
Histoplasma capsulatum
c)
Madurella grisea
d)
Trichophyton mentagrophytes
74.
下列有關Aspergillus niger的敘述,何者是錯的?
a)
為黴菌
b)
菌絲有分隔
c)
菌落反面為黑色
d)
含vesicle構造
75.
下列何種酵母菌非主要致病菌?
a)
Cryptococcus neoformans
b)
Candida spp.
c)
Saccharomyces spp.
d)
Malassezia furfur
76.
不常見細菌中所謂“HACEK”group中之“C”指的是:
a)
Campylobacter
b)
Cardiobacterium
c)
Citrobacter
d)
Clostridium
77.
下列何者具有Phenylalanine Deaminase陽性反應?
a)
Pantoea spp
b)
Klebsiella spp.
c)
Morganella spp.
d)
Yersinia spp.
78.
下列何者不是人畜共通傳染病(zoonosis)?
a)
Brucellosis
b)
Shigellosis
c)
Leptospirosis
d)
Salmonellosis
79.
下列何種黴菌的感染可在組織中找到 Sclerotic bodies?
a)
Cladosporium spp.
b)
Mucor spp.
c)
Epidermophyton spp.
d)
Trichophyton spp.
80.
下列何種黴菌不具microconidia?
a)
Cladosporium
b)
Epidermophyton
c)
Microsporum
d)
Trichophyton
100 %
