Worksheets2009PHM QuizIZZ 1
Total questions: 20
Worksheet time: 12mins
Cardiac output is NOT influenced by
Heart rate
Stroke volume
β1-receptors on the heart
Kidneys
Peripheral resistance
Which of the following are NON-modifiable risk factors?
Waist circumference
Familial hypercholesterolaemia
Age
Salt intake
Diabetes
How are you going in T2 so far?
Excellent
Great
Average
I'm still adjusting
I'm OK
Which of the following is INCORRECT about hypertension drugs?
The efficacies of anti-hypertensive drugs are the same
β-blockers are recommended as first-line therapy
Always check to see if the patient has any co-morbidities
thiazides can be used but only at low doses
ACE inhibitors and ARBs have different mechanisms of action
Which of the following is a drug that selectively blocks the β1- receptor on cardiac tissue?
propranolol
atenolol
formoterol
dosorol
prazosin
Which of the following drugs directly stops the production of Angiotensin II?
perindopril
enalopril
candesartan
ramipril
amyl nitrate
Which of the following anti-hypertensive drugs is an α2-agonist that stops the release of noradrenaline?
prazosin
clonidine
methylxanthine
irbesartan
ethacrynic acid
Check all the following that are features of the dihydropyridines class of anti-hypertension drugs.
Include drugs such as diltiazem and verapamil
Used in first-line treatment of hypertension
Are metabolised by the CYP3A4 liver enzyme
Acts on cardiac tissue
Acts on vascular smooth muscle cells
Check any of the following that are drugs used in hypertensive emergencies.
AT1 receptor blocker
Sodium nitroprusside
Enalopril
Frusemide
Hydralazine
How confident are you in your knowledge of the cardio drug stuff so far?
Extremely
Very
Somewhat
I really need to revise
I haven't even looked at it yet
To reduce platelet aggregation, the mediator that stops being produced when aspirin blocks the COX (cyclooxygenase) enzyme is
thromboxane A2
prostaglandins
leukotrienes
arachidonic acid
lipids
Why do platelets need to have glycoprotein IIb/IIIa receptors on their surface?
To inhibit thrombin
It helps them produce ADP so it can synthesise more platelets
It permits fibrinogen to attach and make crosslinks between platelets
To allow for the binding of COX-1 enzyme tightly to the surface
It generates binding surfaces for collagen on the vascular endothelium
The correct spelling of the antiplatelet drug that acts as a PDE inhibitor is
(a)
From the following drugs, select the ones that are P2Y12 receptor antagonists
warfarin
clopidogrel
prasugrel
ticagrelor
ADP
For the GP IIb/IIIa receptor inhibitors, which of the following drugs mimics the structure of fibrinogen so it cannot form crosslinks between platelets?
warfarin
aspirin
abciximab
eptifibatide
tirofiban
Angina drugs can be used in combination. Which combination of 2 drugs can actually reduce the unwanted adverse effects of each other?
sildenafil + nitrate
perhexiline + nitrate
nitrate + diydropyridine CCB
nitrate + β-blocker
nicorandil + dihydropyridine CCB
Which enzyme is blocked by warfarin?
VMPT
VKOR
VWAR
PDE5
COX
Which main clotting factors are NO LONGER activated due to warfarin's actions?
Factor II
Factor VII
Factor IX
Factor X
Factor XIII
Which of the following statements about warfarin is FALSE?
It is metabolised by the liver CYP2C9 enzyme
It increases the INR
Its response is affected by diet and heavy alcohol use
It may cause skin necrosis or purple toes as adverse effects
It cannot have any effect on a patient's platelet count
From the following list of agents, select those that quickly replace clotting factors in a patient with an INR>20
low molecular weight heparins
phytomenadione
fresh frozen plasma
factor IX concentrate
eptifibatide
