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WorksheetsMOLECULAR BASIS OF INHERITANCE
Total questions: 19
Worksheet time: 10mins
What is the function of primer
To help DNA polymerase for initiation
To help RNA polymerase for initiation
To help DNA polymerase for termination
To help RNA polymerase for termination
DNA replication takes place at _________ phase of the cell
cyle.
G1
S
G2
M
The enzyme DNA dependent RNA polymerase catalyses the polymerisation reaction in ___________direction.
only 5’ → 3’
only 3’ → 5’
both (a) and (b)
none of these
The main enzyme in DNA replication is
DNAse
Proteinase
RNAse
DNA Polymerase
Who proved experimentally that DNA is genetic material?
O. Avery and Colleagues
J. Waston and F. Crick
W. Arber and Colleagues
G. Mendel
The enzyme that restores the phosphodiester linkage between adjacent fragments in the lagging strand during DNA replication is
DNA ligase
primase
reverse transcriptase
helicase
The building blocks for a new DNA molecule are
deoxyribose nucleoside monophosphates
deoxyribose nucleoside diphosphates
deoxyribose nucleoside triphosphates
deoxyribose nucleoside tetraphosphates
The difference between DNA and RNA is that
DNA has thymine and RNA has uracil
DNA has no oxygen bonded to the 2’ carbon; RNA does
DNA is the genetic material; RNA is not.
DNA is double stranded and RNA can’t have hydrogen bond
Which one of the following is not found in DNA?
Carbon
Oxygen
Nitrogen or Hydrogen
Sulfur
The Hershey-Chase experiment
Proved semiconservative replication is the mode for DNA replication
used 32P to label protein
used 35S to label DNA
helped to prove DNA was the genetic molecule
Which of the following types of bacteria were used in Griffith’s transformation experiment?
Diplococcus, R-III and S-II type
Pneumococcus, T2 phage
Streptococcus, R-II and S-III type
Diplococcus, E. coli
In Hershey and Chase experiment, the protein of T2 phage was made radioactive by using
S32
P31
S35
P32
Semiconservative DNA replication was proved by Messelson and Stahl, in which DNA was made
Radioactive using N15
Heavy using 14NH4Cl
Heavy using 15NH4Cl
Radioactive using 14NH4Cl
During DNA replication which of the following does not act as substrates?
dATP
dCTP
dUTP
dGTP
RNA primer is removed by
DNA-P-I
DNAP-II
DNAP-III
Primase
Which of the following acts as substrate as well as provide energy for DNA polymerisation?
Ribonucleoside
Deoxyribonucleoside
Ribonucleotide
Deoxyribonucleoside triphosphate
DNA replication is
Semi-conservative, continuous, unidirectional
Conservative, continuous
Semi-conservative, semi-discontinuous
Semi-continuous, conservative
The leading strand and lagging strand in DNA replication differ in that only on the lagging strand
DNA is replicated as short fragments
RNA primer is present
Replication proceeds in the 5’ to 3’ direction
Okazaki fragments are not needed
In semiconservative replication of DNA
the original double helix remains intact and a new double helix forms
the strands of the double helix separate and act as templates for new strands
polymerization is catalyezed by RNA polymerase
polymerization is catalysed by a double helical enzyme
