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Pharm Lecture 1 and 2 - Allergy

Total questions: 52

Worksheet time: 35mins

Name
Class
Date
1.

Which agents(s) can be used to treat an infection caused by Bacteroides sp.?

a)

Metronidazole

b)

Cetriaxone

c)

Meropenem

d)

Azithromycin

e)

Piperacillin/tazobactam

2.

Which of the following is an appropriate treatment use of Clindamycin?

a)

Enterococcus urinary tract infection

b)

Peptostreptococcus dental abscess

c)

Klebsiella pneumonia

d)

Clostridium difficile-associated diarrhea

3.

Which agents will cover Streptococcus pneumoniae?

a)

Penicillin

b)

Vancomycin

c)

Aztreonam

d)

Clindamycin

e)

Ceftriaxone

4.

Macrolides

a)

bactericidial

b)

bacteriostatic

c)

AUC:MIC dependent

d)

concentration dependent

5.

Fluroquinolones

a)

bactericidial

b)

bacteriostatic

c)

AUC:MIC dependent

d)

concentration dependent

6.

best absorption of fluoroquinolones

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

7.

Once a day dosing

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

8.

MRSA coverage

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

9.

MSSA coverage only

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

10.

anaerobe coverage

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

11.

atypical coverage

a)

macrolides

b)

fluoroquinolones

12.

UTI

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

13.

UTI uses

a)

Macrolides

b)

Fluoroquinolones

14.

Treatment/prophylaxis in bioterrorism

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

15.

First line options for UTI

a)

Nitrofurantoin

b)

TMP/SMX

c)

Levofloxacin

d)

Ciprofloxacin

16.

Acute bacterial sinusitis (ABS) for first-line therapy for empiric treatment

a)

fluoroquinolones

b)

beta-lactams

17.

acute bacterial exacerbation of chronic bronchitis (ABECB) first-line recommended agents

a)

aminopenicillins

b)

doxycycline

c)

TMP/SMX

d)

levofloxacin

e)

moxifloxacin

18.

Community acquired pneumonia (CAP) [S. pneumoniae, H. influenzae, atypicals]

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

19.

Hospital-acquired pneumonia (HAP) or ventilator-associated pneumonia (VAP) [gram neg pathogens, Psudomonas aeruginosa most concerning]

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

20.

UTIs

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

21.

GI infections (alternative treatment to traveler's diarrhea)

a)

Ciprofloxacin (plus metronidazole)

b)

Levofloxacin (plus metronidazole)

c)

Moxifloxacin

d)

Delafloxacin

22.

Skin and Skin Structure infections

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

23.

rarely used for empiric therapy ( bc of their limited activity against MRSA)

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

24.

only for gram-negative skin infections

a)

Ciprofloxacin

b)

Levofloxacin

c)

Moxifloxacin

d)

Delafloxacin

25.

safe in pregnancy and lactation

a)

macrolides

b)

fluoroquinolines

26.

muscoskeletal risk in pregnancy/lactation, children/neonates, and elderly

a)

macrolides

b)

fluoroquinolones

27.

cardiac arrhythmias risk in elderly

a)

macrolides

b)

fluroquinolones

28.

safe in children and neonates

a)

macrolides

b)

fluroquinolones

29.

no issues in obesity

a)

macrolides

b)

fluroquinolones

30.

Streptococcus pyogenes (Group A)

a)

Azithromycin

b)

Ciprofloxacin

c)

Levofloxacin

d)

Moxifloxacin

e)

Delafloxacin

31.

Streptococcus pneumoniae

a)

Azithromycin

b)

Ciprofloxacin

c)

Levofloxacin

d)

Moxifloxacin

e)

Delafloxacin

32.

Haemophilus influenzae

a)

Azithromycin

b)

Ciprofloxacin

c)

Levofloxacin

d)

Moxifloxacin

e)

Delafloxacin

33.

Moraxella catarrhalis

a)

Azithromycin

b)

Ciprofloxacin

c)

Levofloxacin

d)

Moxifloxacin

e)

Delafloxacin

34.

Staphylococcus aureus (LRT infection)

a)

Beta-lactam

b)

Vancomycin

c)

Azithromycin

d)

Levofloxacin

35.

Atypical bacteria

a)

Azithromycin

b)

Any FQ

36.

Bortatella pertussis

a)

Azithromycin

b)

Any FQ

37.

Upper respiratory bugs

a)

Azithromycin

b)

Ciprofloxacin

c)

Levofloxacin

d)

Moxifloxacin

e)

Delafloxacin

38.

Metronidazole

a)

bactericidial

b)

bacteriostatic

c)

AUC:MIC dependent

d)

concentration dependent

39.

Metronidazole MOA

a)

protein-synthesis inhibitor

b)

DNA synthesis inhibitor

c)

Free radical production (cytotoxic)

40.

Fluoroquinolones MOA

a)

protein-synthesis inhibitor

b)

DNA synthesis inhibitor

c)

Free radical production (cytotoxic)

41.

Macrolides MOA

a)

protein-synthesis inhibitor

b)

DNA synthesis inhibitor

c)

Free radical production (cytotoxic)

42.

Clindamycin MOA

a)

protein-synthesis inhibitor

b)

DNA synthesis inhibitor

c)

Free radical production (cytotoxic)

43.

Trichomonas vaginalis drug of choice

a)

Clindamycin

b)

Metronidazole

c)

Azithromycin

d)

Ciprofloxacin

44.

Clindamycin

a)

bactericidial

b)

bacteriostatic

c)

AUC:MIC dependent

d)

concentration dependent

45.

Top 200 drug

a)

Azithromycin

b)

Ciprofloxacin

c)

Clindamycin

d)

Metronidazole

46.

Metronidazole coverage

a)

Aerobes, gram + only

b)

Anaerobes, gram +

c)

Anaerobes, gram -

47.

Clindamycin coverage

a)

Aerobes, gram + only

b)

Anaerobes, gram +

c)

Anaerobes, gram -

48.

SSTI including necrotizing fasciitis and acne vulgarius

a)

clindamycin

b)

metronidazole

49.

alternative to cefazolin for surgical prophylaxis in patients w severe PCN allergy

a)

clindamycin

b)

metronidazole

50.

no adjustment in renal or hepatic failure

a)

clindamycin

b)

metronidazole

51.

best above the diaphragm

a)

clindamycin

b)

metronidazole

52.

best below the diaphragm

a)

clindamycin

b)

metronidazole

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