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Demystifier Hepatite

Total questions: 25

Worksheet time: 13mins

Name
Class
Date
1.

What was the theme for World Hep Day 2020 and 2021 respectively ?

a)

Hepatitis can't wait, Hepatitis-free future

b)

Hepatitis-free future, Hepatitis can't wait

c)

Hepatitis-free future, Hepatitis won't wait

d)

Hepatitis can wait, Hepatitis-free future

2.

Who won the Nobel prize for Medicine in 2020 for the discovery of Hep C virus and when?

a)

Harvey J Alter, Charles M Rice and Michael Houghton - 5th Oct

b)

Jeffrey C Hall, Michael Roshbash and Michael W Young - 28th July

c)

Harvey J Alter, Charles M Rice and Michael Houghton - 28th July

d)

Jeffrey C Hall, Michael Roshbash and Michael W Young - 4th Oct

3.

Drug of choice for Hepatitis D

a)

Alpha interferon

b)

Tenofovir

c)

Tenofovir + Alpha interferon

d)

Ledipasvir

4.

Which of the following antigens is never seen in the blood of a hepatitis B patient

a)

HBs Ag

b)

HBe Ag

c)

HBc Ag

d)

All are present

5.

A patient's Hep B Ab panel is positive for both HBc IgG and HBs Ab but negative for HBs Ag. The correct interpretation of the results would be that the patient

a)

Is chronically infected with Hep B

b)

Has never been exposed to Hep B

c)

Has had acute Hep B in the past, but the infection has now resolved

d)

Has had chronic Hep B in the past, but the disease responded to interferon therapy

e)

Has been vaccinated for Hep B

6.

What is the difference between Hep A, Hep B and Hep C ?

a)

Only Hep A affects the liver

b)

They cause different symptoms

c)

Hep A does not become chronic

d)

There is a vaccine for Hep C but not Hep A

7.

Which agent represents an isolate of Hep G virus ?

a)

GBV-C

b)

GBV-B

c)

GBV-E

d)

None of the above

8.

Vaccine preventable hepatitides include

a)

Hep A and Hep C

b)

Hep B and Hep C

c)

Hep B only

d)

Hep A and Hep B

9.

Which area of the liver is first affected by hepatitis viruses?

a)

Periportal zone

b)

Middle zone

c)

Centrilobular zone

d)

All affected simultaneously

10.

Viral Hepatitis is defined as 'acute' if it lasts for

a)

Less than 6 weeks

b)

Less than a month

c)

Less than 6 months

d)

Less than 8 months

11.

What is the therapy of choice in an acute viral Hepatitis E infection

a)

Observe

b)

IV fluids

c)

Pegylated interferon

d)

Lamivudine

12.

Connect (Keep it short!)

(a)  

13.

The graph illustrates the serological findings in a patient with chronic HBV infection


ID A, B and C

a)

HBsAg, anti-HBs-IgG, anti-HBs-IgM

b)

HBsAg, anti-HBc-IgG, anti-HBc-IgM

c)

HBcAg, anti-HBs-IgM, anti-HBs-IgG

d)

HBsAg, anti-HBc-IgG, anti-HBs-IgG

14.

CDC recommends Hep C screening for all of the following high-risk populations, except-

a)

Children born to HCV positive women

b)

Patients who have had long-term hemodialysis

c)

Persons born between 1945 and 1965

d)

Persons with chronic HBV infection

15.

A 50 year old male has past history of acute hepatitis B infection 20 years ago, for which he did not follow up. Which of the following might NOT be present in this patient?

a)

Normal liver function

b)

Nutmeg liver

c)

AST >> > ALT

d)

Nuclear atypia

16.

What percentage of acute HBV infections resolve completely?

a)

20% (it is scary)

b)

70% (decent chance)

c)

95% (too good to be true?)

d)

50% (dichotomy of life)

17.

As a HCW, you have received a full regimen of vaccination against HBV. Your antibody titers following the third dose were measured to be 6 mIU/mL. You got exposed to the blood of a HBsAg + patient. What is the next course of action?

a)

Nothing

b)

HBIG

c)

HBIG + Vaccine booster dose

d)

HBIG + Full regimen of vaccination

18.

Hepatitis virus gene responsible for carcinogenesis is -

a)

S gene

b)

X gene

c)

C gene

d)

P gene

19.

Assertion: Hepatitis B virus can be transmitted by mosquitoes

Reason: Hepatitis B virus can survive in mosquitoes

a)

Both, A and R, are true and R is the correct explanation of A

b)

Both, A and R, are true but R is not the correct explanation of A

c)

A is false but R is true

d)

Both A and R are false

20.

How many of the following Hepatitis viruses can potentially cause immune-complex mediated manifestations? (Type in a number between 0-4)

(a)  

21.

Connect. Type a single letter - Hep (a)  

22.

HCV can be transmitted sexually and perinatally, however these modes of transmission are ineffective for Hep C

a)

True

b)

False

23.

As an HCW, you had previously shown adequate titers following HBV vaccination, but your titers are now declining. You should -

a)

Get a booster dose

b)

Follow up with regular antibody titer testing

c)

Trust your immune system

d)

Get revaccinated with the entire post-exposure prophylaxis regimen

24.

Which of the following pathologies is not seen in a liver infected with acute viral hepatitis ?

a)

Councilman bodies

b)

Numerous mitotic figures in hepatocytes

c)

Extensive bile duct lesions

d)

Panlobular infiltrates of lymphocytes

25.

Which of the following is not a risk factor for developing fulminant hepatitis ?

a)

HBV infection with underlying chronic HCV infection

b)

HDV infection

c)

HCV infection

d)

Pregnant females with HEV infection