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GLP1-RA

Total questions: 10

Worksheet time: 5mins

Name
Class
Date
1.

Which of the following have demonstrated cardiovascular benefit compared with placebo?

a)

Liraglutide

b)

Oral semaglutide

c)

SQ semaglutide

d)

dulaglutide

e)

exenatide

2.

Which of the following is true of GLP-1 but not true of GIP?

a)

Increases insulin secretion

b)

Beta-cell sparing

c)

Decreases glucagon secretion

d)

Degraded by DPP-4

3.

T/F: Long-acting agents have been shown to have a greater effect on both A1c reduction and weight loss.

a)

True

b)

False

4.

T/F: You cannot be started on a GLP1-RA if you have ESRD.

a)

True

b)

False

5.

The following GLP1-RA carries a risk of retinopathy:

a)

semaglutide

b)

dulaglutide

c)

liraglutide

d)

exenatide

6.

Which of the following recommendations is true?

a)

GLP-1RA are recommended in patients with a history of pancreatitis

b)

GLP-1RA are recommended for patients with type 2 & type 1 diabetes

c)

It is OK to take GLP-1RA with DPP-4 inhibitors, as long as you monitor for hypoglycemia

d)

Patients with a history of thyroid cancer should avoid using GLP-1RA

7.

T/F: There are no GLP1-RA products approved for weight loss.

a)

True

b)

False

8.

Short-acting agents target ____ glucose while long-acting agents have _______.

a)

post-prandial; a mixed effect

b)

pre-prandial; a worse effect

c)

fasting; a post-prandial effect

d)

post-prandial; no effect

9.

T/F: Injection site reactions are more common in long-acting agents as opposed to short-acting.

a)

True

b)

False

10.

A 50 y/o overweight female with T2DM is currently on metformin 1 gm BID. Her post-prandial BG is not at goal and her A1C is 7.7%. She is terrified of needles and does not want to inject any medication. What option would benefit her the most at this time?

a)

Change metformin to glipizide

b)

Increase metformin to 850 mg TID

c)

Oral semaglutide

d)

Diet and exercise only