WorksheetsQUIZ 3
Total questions: 40
Worksheet time: 20mins
ALL are true of Diphtheria toxin, EXCEPT:
double chain
three-domain polypeptide
heat-stable
All are correct
This is a typical findings of what specie? *
Clostridium tetani
Clostridium botulinum
All of the above
Clostridium perfringens
Invasiveness of the Corynebacterium diphtheriae is dependent on the: *
Bacterial gene
Host gene
Phage gene
All are true
Germination of the spore and development of vegetative organisms that produce toxin in Clostridium tetani is aided by *
Calcium salts
Absence of necrotic tissue
All of the above
Not associated with pyogenic infections
What is the minimum lethal dose of Diphtheria toxin? *
0.1 ug/kg/body weight
0.001 ug/kg/body weight
1.0 ug/kg/body weight
0.01 ug/kg/body weight
The incubation period in inhalation anthrax is *
6 days
3 days
6 months
6 weeks
These cause food poisoning and opportunistic infections in immunocompromised patients *
Bacillus anthracis and Bacillus cereus
Bacillus cereus
Bacillus cereus and Bacillus thuringiensis
Bacillus thuringiensis
one of the coryneform bacteria most commonly isolated from acutely ill patients. *
Corynebacterium jeikeium
Corynebacterium xerosis
Corynebacterium minutissimum
Corynebacterium urealyticum
Any of the choices is correct
Bacillus anthracis is acquired through which of the following entry? *
Cutaneous
Gastrointestinal
Inhalation
All of the above
Toxigenicity of the Corynebacterium diphtheriae is dependent on the: *
All are true
Bacterial gene
Phage gene
Host gene
What are the organs affected in disseminated Nocardiosis? *
Liver and Gallbladder
Brain and Skin
Gastrointestinal Tract
Pancreas
Which of the following is the characteristic of emetic form of Bacillus cereus? *
Incubation period of 1-24 hours
Occasional diarrhea
Fever and vomiting
Profuse diarrhea
Which of the following causes diphtheria? *
Corynebacterium diphtheria
Corynebacterium pseudotuberculosis
All are correct
Corynebacterium ulcerans
Myonecrosis and gas gangrene are findings of *
Clostridium difficile
Clostridium botulinum
Clostridium tetani
Clostridium perfringens
Treatment of choice for Erysipeloid: *
Penicillin
Cephalosphorins
Macrolides
trimethoprim–sulfamethoxazole
Which of the following is most commonly isolated coryneform bacteria from clinical material. *
All are correct
Corynebacterium minutissimum
Corynebacterium striatum
Corynebacterium xerosis
The motility that Listeria monocytogenes has is: *
Falling- leaf motility
Tumbling motility
Gliding motility
Jumping
Alternatives to penicillin in treating Bacillus cereus infection include *
Doxycline
Erythromycin
Ciprofloxacin
All of the above
Identify based on the morphology *
Clostridium tetani
Listeria monocytogenes
Actinomycetes
Bacillus subtilis
Which of the following antibiotics are associated with Pseudomembranous colitis? *
Fluoroquinolones
All of the above
Ampicillin
Clindamycin
Which is true to Diphtheria toxoid: *
Should be given to immunocompromised patients
commonly combined with tetanus toxoid (Td) and with acellular pertussis vaccine (DaPT)
All are true
commonly combined with measles
this technology allows for assessment of ribosomal proteins whose spectral patterns are unique enough to identify organisms to the species level *
MALDI-TOF-MS
Gas Liquid Chromatography
Polymerase Chain Reaction
Culture
Among the four biotypes of Corynebacteria, which produce more severe disease? *
intermedius
mitis
Gravis
belfanti
The in-vitro production of Diphtheria toxin depends largely on the concentration of: *
Sulfur
Copper
Iron
magnesium
Which of the following organism have these findings? *
Bacillus cereus
Clostridium difficile
Bacillus subtilis
Clostridium perfringens
Comma shaped outgrowths (Medusa head) that project from the colony are characteristic finding of *
Clostridium tetani
Bacillus anthracis
Listeria monocytogenes
Corynebacterium bacteroides
Gram- positive, spore forming bacilli, thin, branching and beaded modified acid-fast positive rods, chalky white colonies and infrequent cause of infection: *
Nocardia brasiliensis
Nocardia nova complex
Nocardia asteroides
Nocardia farcinica
The most common offenders of Clostridium botulinum include *
Canned alkaline food
All of the above
Spiced food and smoked food
Vacuum packed
This is associated with what infection? *
Clostridium botulinum
All of the above
Clostridium tetani
Clostridium perfringens
The following are features of Clostridium botolinum *
Resistant to heat and withstand 100 degree celsius
Heat resistance is diminished at acid pH or high salt concentration
All of the above
Found in soil and in animal feces
Mode of transmission of Nocardia? *
Ingestion
Person to Person
Inhalation
Close contact
Polymerase chain reaction (PCR)–based methods have been described for detection of what diphtheria toxin gene
E gene
N2 gene
tox
tax
This is a major potential agent of bioterrorism and biologic warfare *
Bacillus subtiliis
Bacillus anthrax
Bacillus cereus
Bacillus thuringiensis
A 25 yo, female, went to a party, had wine and cheese, after 48 hours, the patient had onset of fever, chills, headache, myalgia, abdominal pain and diarrhea. Which of the following is true of her condition? *
She got it from ingestion of wine
Self- limited
May lead to sepsis if not treated properly
All are correct
A form of adenylate cyclase *
Lethal factor
Protective antigen
All of the above
Edema factor
This is true about Cutaneous eschar *
The vesicles rapidly change into papules
A pruritic papule develops 14 days after the entry of the organisms or spores
Generally occurs in frequency by the face and neck followed on exposed surfaces of the arms
The lesions have a central black eschar
Treatment of choice for Nocardiosis: *
Cephalosphorins
Macrolides
Penicillin
trimethoprim–sulfamethoxazole
What is the most important aspect of treatment in myonecrosis? *
All of the above
Administration of antibiotics
Extensive surgical debridement of the involved area and excision of all devitalized tissue
Vaccine administration
Bacillus cereus is a soil organism that commonly contaminates *
Honey
All of the above
Rice
Milk and dairy products
Mode of transmission of Diphtheriae: *
droplet
blood borne
airborne
ingestion
