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Transcription and Lac operon

Total questions: 20

Worksheet time: 30mins

Name
Class
Date
1.

During transcription _________

a)

DNA is made complimentary to RNA

b)

RNA is made complimentary to DNA

c)

a protein is made from the RNA base sequence

d)

a protein is made from the DNA base sequence

2.

RNA is synthesized on a DNA template in a process called ______, which utilizes the enzyme _______

a)

translation, RNA polymerase

b)

transcription, DNA polymerase

c)

transcription, RNA polymerase

d)

replication, DNA polymerase

3.

Given the following DNA strand, which of the following is its complementary mRNA? 3’ G G A C T G A T T 5’

a)

3’ C C U G A C U A A 5’

b)

5’ C C U G A C U A A 3’

c)

5’ G G A C T G A T T 3’

d)

3’ T T A G T C A G G 5’

4.

Once transcription has been completed, which of the following is NOT necessary for protein synthesis to occur?

a)

tRNA

b)

ribosomes

c)

mRNA

d)

DNA

5.

Which site of the tRNA molecule binds to the mRNA molecule?

a)

Anticodon

b)

Codon

c)

amino acid

d)

5’ end

6.

What is the basic role of mRNA?

a)

transfer the amino acids to the ribosome

b)

transfer the amino acids to the nucleus

c)

transfer the DNA message to the ribosome

d)

transfer the mRNA message to the nucleus

7.

What is the role of the ribosome in protein synthesis?

a)

it is where mRNA synthesis occurs

b)

it is where DNA synthesis occurs

c)

it is where protein synthesis occurs

d)

it is where gene synthesis occurs

8.

If the DNA code reads CCAATTGG then the tRNA code would read ____________

a)

CCAATTGG

b)

CCAAUUGG

c)

GGUUAACC

d)

GGTTAACC

9.

Introns are

a)

Noncoding sequence of mRNA

b)

Coding sequence of mRNA

c)

Complex of molecules that cut out the introns and splice together the exons

d)

Involves the removal of introns, fusing of the exons, and the addition of a 5’ cap and a Poly A tail to mRNA

10.

All of the following is true about pre-mRNA that is produced in eukaryotes EXCEPT

a)

Consist of intron and exon

b)

Carry genetic information for specific protein synthesis

c)

Will be used as template in translation process

d)

Synthesized in nucleus during transcription

11.

Functioning unit of DNA containing a cluster of genes under the control of a single regulatory signal or promoter is termed as

a)

Operon

b)

Operator

c)

Lac

d)

Repressor protein

12.

Which of the following conditions leads to maximal expression of the lac operon?

a)

lactose present, glucose absent

b)

lactose present, glucose present

c)

lactose absent, glucose absent

d)

lactose absent, glucose present

13.

Lac operon can be found in

a)

E. coli

b)

lactose

c)

human colon

d)

glucose

14.

The structural gene that codes for protein that increase the permeability of the plasma membrane towards lactose is.

a)

lacI

b)

lacZ

c)

lacY

d)

lacA

15.

What is the enzyme that detoxifies other molecules entering the cell via the permease?

a)

β-galactosidase

b)

β-galactoside primase

c)

β-galactoside permease

d)

β-galactoside transacetylase

16.

What happen to lac operon in the absence of lactose?

a)

lac operon is switched off

b)

lac operon is active

c)

repressor protein bind to promoter

d)

RNA polymerase binds to operator

17.

Which of the following is active in the absence of lactose?

a)

lacI

b)

lacZ

c)

lacY

d)

lacA

18.

Which sentence is TRUE about structural genes in the absence of lactose?

a)

Transcription occurred to synthesis enzyme

b)

Translation occurred to synthesis mRNA

c)

Transcription occurred to synthesis mRNA

d)

No transcription and translation occurred

19.

If a promoter was being deleted in lac operon, what would be the effect towards lac operon in the absence of lactose?

a)

RNA polymerase can transcribe the structural genes

b)

Enzymes are being produced

c)

Repressor protein will change its shape

d)

RNA polymerase cannot bind to lac operon

20.

In the absence of glucose, the lac operon system is activated when the person consumes the following, EXCEPT

a)

soy milk

b)

yoghurt

c)

cream cheese

d)

milkshake