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All about GSDs

Total questions: 15

Worksheet time: 8mins

Name
Class
Date
1.

Which disease is autosomal recessive

a)

Cori’s disease

b)

Von Gierke’s disease

c)

Anderson’s disease

d)

Hers disease

2.

Which GSD is characterised by infantile Cardiomegaly

a)

Pompe’s disease

b)

Coris disease

c)

McArdles disease

d)

Tarui’s disease

3.

Which GSD mainly affects the skeletal muscle

a)

Type I

b)

Type II

c)

Type VI

d)

Type V

4.

Which GSD is because of deficiency of Glucosyl 4-6 transferase (branching enzyme)

a)

Anderson’s

b)

Pompes

c)

von Gierkes

d)

Hers

5.

Which GSD is responsible for severe fasting hypoglycaemia, lactic academia and hyperuricemia leading to gout

a)

von Gierkes

b)

Pompes

c)

Anderson’s

d)

Coris

6.

Which GSD leads to increased accumulation of long insoluble glycogen chains

a)

pompes

b)

McArdles

c)

Anderson’s

d)

Coris

7.

Which GSD is because of lysosomal Alfa 1-4 glucosidase

a)

Hers

b)

Pompes

c)

Coris

d)

Anderson’s

8.

Which GSD is not because of extra glycogen storage in the liver

a)

GSD 0

b)

Type V

c)

Type II

d)

Type I

9.

Hers disease is because of deficiency of which enzyme

a)

Hepatic glycogen phosphorylase

b)

Amylo Alfa 1,6 glucosidase

c)

Phosphofructokinase

d)

Muscle glycogen phosphorylase

10.

Coris disease generally affects

a)

Liver

b)

Muscle

c)

Heart and leukocytes

d)

All

11.

Which GSD is due to glucose 6 phosphatase deficiency

a)

Type I

b)

Type III

c)

Type V

d)

Type VI

12.

Name of Type III GSD

a)

Pompes

b)

coris

c)

McArdles

d)

Hers

13.

Which disease is characterised by diaphragm weakness leading to respiratory failure

a)

Pompes

b)

Coris

c)

Von gierkes

d)

Taruis

14.

Anderson’s disease is because of deficiency of

a)

Alfa 1,4 glucosidase

b)

Alfa 1,6 glucosidase

c)

Glucosyl 4,6 transferase

d)

Glucose 6 phosphatase

15.

Most common GSD

a)

von Gierkes

b)

Coris

c)

Pompes

d)

Anderson’s