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WorksheetsExam 3 Pain
Total questions: 16
Worksheet time: 9mins
What are the primary afferent fibers for pain?
Aδ and C
A B and C
Aγ and C
Bγ and C
Check the two correct ascending pathways for pain:
Sensory-discriminative - components and processes for detecting pain
Regulatory-Limbic - Processing of pain and appropriate response
Motivational-affective - individual response to limbic cortex
Which of the fibers are responsible for fast pain response?
C
D
Aδ
Gamma
What best describes pain threshold?
Max pain a person is able to tolerate
Time and intensity of pain endurance
point on a curve of increasing perception of a stimulus at which pain begins to be felt
Higher in children but not likely to be present in a fetus
What is the incorrectly matched migraine phase?
Prodrome - mood changes, neck pain
Postdrome - fatigue, difficulty concentrating, cognitive dysfunction
Headache - nausea, vomiting, vasoactive neuropeptides, etc.
Aura - increased cortical activity and blood flow
Check the potential etiologies of migraines:
Vascular - vasodilation and other abnormalities
Neurotransmitters - increased CGRP and low serotonin
Cortical Spreading Depression (CSD) - propagating depolarization wave in cerebral cortex
CSD - pannexin-1 closing
Check the effects of CGRP
vasoconstriction
vasodilation
neurogenic inflammation
transmission of pain
What gender is up to 9x more likely to develop fibromyalgia
women
men
Which of the following is a correct diagnosis criteria for fibromyalgia?
11/18 points tender
9/18 points tender
very localized pain
dermatomic fatigue
What is the purpose of tricyclic antidepressants for fibromyalgia use?
Treating neuropathic pain
Improving sleep
Increasing fatigue
Treating focal tenderness
What are the purposes of pregabalin, duloxetine, and milnacipran for fibromyalgia?
treating focal tenderness
increasing fatigue
increasing exercise and stress management
Complicating patients' medication regimens
When is lasmiditan used in migraine treatment?
When -gepants can't be used
When -triptans and dihydroergotamine can't be used (CV effects)
When metoclopramide or prochlorperazine can't be used
When the patient has no CGRP
What is the target of Erenumab?
CGRP receptor
CD52
pannexin-1 megachannels
CGRP ligand
What is the target of fremanezumab?
CGRP receptor
CGRP ligand
beta 3
enkephalin
What is the mechanism of Botox in migraine treatment?
Increasing acetylcholine release
Increasing acetylcholine reuptake
Decreasing acetylcholine release
Decreasing acetylcholine reuptake
Select all of the following that can be used for acute migraine
Sumatriptan-Naproxen
Zolmitriptan
Botox
Galcanezumab SQ inj
