Free Printable BIOSPLENDID 3.1

1.

1. Which genetic abnormality is caused by base deletion?

a)

Thalassaemia

b)

Down syndrome

c)

Sickle cell anaemia

d)

Klinefelter syndrome

2.

2. Thalassaemia is caused by the following type of gene mutation with

a)

Substitution of a base.

b)

Insertion of a base.

c)

Deletion of a base.

d)

Inversion of a base.

3.

3. In sickle-cell anaemia,

a)

Glutamic acid is substituted with valine on the polypeptide chain of haemoglobin S.

b)

Glutamic acid is substituted with proline on the polypeptide chain of haemoglobin S.

c)

Valine is substituted with glutamic acid on the polypeptide chain of haemoglobin S.

d)

Valine is substituted with proline on the polypeptide chain of haemoglobin S.

4.

4. Cri-du-chat syndrome is a result of

a)

Non-disjunction of the sex chromosomes.

b)

Non-disjunction of the chromosome 21.

c)

Deletion of the short arm of chromosome 5.

d)

Gene mutation.

5.

5. What would be the end products of meiosis if non-disjunction of chromosome 21 occurs during meiosis I?

a)

Two daughter cells with two chromosomes 21 and two daughter cells without chromosome 21

b)

Two daughter cells with two chromosomes 21 and two daughter cells with one chromosome 21

c)

Two daughter cells with one chromosome 21, one daughter cell with two chromosomes 21, and one daughter cells without chromosome 21

d)

Four daughter cells with one chromosome 21

6.

6. Which is TRUE of a person suffering from Down syndrome?

a)

The person has long limbs.

b)

The person has one extra autosome.

c)

The somatic cells contain 46 chromosomes.

d)

is a result of disjunction during gamete formation in one of the parents.

7.

7. In a plant species, a diploid gamete is fertilized by a normal haploid gamete, producing a triploid plant. Which is TRUE of this plant?

a)

It is an example of aneuploidy plant.

b)

It will not be able to undergo sexual reproduction.

c)

It will produce fruits-which-are larger with more seeds.

d)

It would look completely different from the normal plant.

8.

8. Which statement BEST describes a recombinant DNA?

a)

DNA which carries genes from different organisms.

b)

DNA which results from bacteria reproduction-conjugation.

c)

DNA which is produced from crossing over.

d)

DNA which is produced from a mutation.

9.

9. What is the importance of restriction endonucleases in a bacterial cell?

a)

It enables bacterial autolysis to occur.

b)

It provides resistance against antibiotics.

c)

It destroys antigens and neutralizes toxin.

d)

It cuts viral DNA molecules into fragments.

10.

10. Which of the following are restriction enzymes?

I EcoRI

II Plasmid

III Ampicillin

IV SmaI

a)

I and III

b)

II and III

c)

I and IV

d)

III and IV

11.

11. Which are TRUE about restriction enzymes?

I A type of endonuclease

II Join two DNA fragments

III Use to cut DNA and RNA

IV Naturally found in some bacteria

a)

I and III

b)

I and IV

c)

II and III

d)

II and IV

12.

12. Screening is

a)

The process of choosing the clone which has undergone transformation.

b)

The process of producing a transgenic organism.

c)

The insertion of a foreign gene into a vector.

d)

The insertion of a vector into a host cell.

13.

13. What is the fragment of DNA that has no intron and is synthesized using mRNA as a template?

a)

Complementary DNA

b)

Recombinant DNA

c)

Cloned DNA

d)

Okazaki fragment

14.

14. Why is cDNA used in some cloning processes instead of the original DNA?

I The original DNA contains exons and introns

II cDNA does not contain introns

III Bacteria cannot process exons

IV Bacteria cannot process introns

a)

I, II and III

b)

I, II and IV

c)

II, III and IV

d)

I, II, III and IV

15.

15. Which biotechnology applications have been used to benefit human being?

I Production of vitamin A-enriched rice grains.

II Insertion of antibiotic-resistance genes in human somatic cells.

III Production of blood clotting factors to treat thalassaemia.

IV Production of cotton trees which are herbicide resistant.

a)

I and II

b)

II and IV

c)

I and IV

d)

I, III and IV

16.

16. The following are the application of biotechnology EXCEPT to

a)

Improve yields of crops

b)

Clean the environment

c)

Produce therapeutic products

d)

Improve the quality of human genes

17.

17. Some of the advantages of transgenic plants are

I create super weeds

II delay the ripening of fruits

III reduce weed species on farmlands

IV resistant to insecticides

a)

I and III

b)

I and IV

c)

II and III

d)

II and IV

BIOSPLENDID 3.1

Total questions: 17

Worksheet time: 9mins

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