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Signal Transduction

Total questions: 19

Worksheet time: 15mins

Name
Class
Date
1.

Which step would be the final step in a signal transduction pathway?

a)

phophorylation of proteins

b)

activation of protein

c)

change in gene expression

d)

binding a ligand to a receptor

2.

Which step would be the first step in a signal transduction pathway?

a)

phophorylation of proteins

b)

activation of protein

c)

change in gene expression

d)

binding a ligand to a receptor

3.

What is the role of protein kinase in a signal transduction pathway?

a)

activates a molecule by adding a phosphate to the target molecule

b)

deactivate a molecule by removing a phosphate from the target molecule

c)

activates a molecule by removing a phosphate from the target molecule

d)

deactivate a molecule by adding a phosphate to the target molecule

4.

What is the purpose of transduction?

a)

send a signal to a target cell

b)

receive a signal from another cell

c)

respond to a signal pass along internally

d)

pass along a signal through the cell to the location where the cell response will occur.

5.

Once a cell responses to a signal, what would need to occur to stop the response?

a)

activate the relay proteins

b)

deactivate the relay proteins

c)

destroy the cell

d)

genetically modify the DNA of the cell

6.

Phosphorylation is the process by which a ____ is added to a protein to activate it.

a)

acetyl

b)

sulfate

c)

phosphate

d)

nitrate

7.

What class of enzymes performs phosphorylation?

a)

catalases

b)

phosphatases

c)

kinases

d)

amplifases

8.

What is the advantage to amplification of a signal inside of a cell?

a)

moderates the signal so it is not to quick

b)

stops a signal from being transducted

c)

increases the cell response to a signal

d)

increases the reception of signal

9.

What class of enzymes removes phosphate from proteins to deactivate them?

a)

catalases

b)

phosphatases

c)

kinases

d)

amplifases

10.

All mammals have a similar signaling pathway for the uptake of glucose by cells from the blood. What does this suggest about the evolutionary relatedness

a)

Species that use the same signal pathway are probably closely related by evolution.

b)

Species that use the same signal pathway are probably not closely related by evolution

c)

Species that use the same signal pathway will look the same anatomically

d)

Species that use the same signal pathway would not be in the same kingdom.

11.

(a)   is a process that adds a phosphate group onton a protein to "activate" it.

12.

In question 9a, which steps in the phosphorylation cascade illustrated in Model 2 include phosphorylation? (Check all that apply)

a)

3

b)

4

c)

5

d)

6

e)

7

13.

Identify the steps in Model 2 that represent reception, transduction and response for the phosphorylation pathway (question 11).

Categorize the following

Step 1

Step 2

Step 3

Step 4

Step 5

Step 6

Step 7

Reception
Transduction
Response
14.

(Question 3) Label the diagram with the to indicate where each step takes place.

15.

(Question 20a) Describe the type of diffusion that is used to get the secondary messengers into the cell in Model 3.

a)

Simple Diffusion

b)

Osmosis

c)

Facilitated Diffusion

d)

Phagocytosis

16.

Reorder the following steps in a signal transduction pathway

a)

A signal molecule is generated

b)

Signal molecule binds to a receptor

c)

Activated receptors activate a transduction pathway

d)

Signal results in a the cell responding

1)
2)
3)
4)
17.

(Question 7) Once the response is achieved in a cell, what would need to occur to stop the response?

a)

Activated relay proteins need to be deactivated

b)

A new signal molecule must bind to a new receptor

c)

Transduction pathway moves through the cell

d)

Cell runs out of resources to respond

18.

What is the correct order of the steps shown in the diagram?

a)

transduction, reception, response

b)

reception, transduction, response

c)

response, reception, transduction

d)

reception, response, transduction

19.

What is being depicted in the image?

a)

Amplification of the signal molecule

b)

Enzymatic proteins inhibiting process of the signal transduction pathway

c)

Kinase groups adding dimer groups to other enzymes

d)

Diffusion of molecules within the cell due to the signaling molecule