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Ophthalmic Preparations (Long)

Total questions: 9

Worksheet time: 4mins

Name
Class
Date
1.

What is the disadvantage of systemic route in the treatment of ocular disease?

a)

The systemic route requires higher dose compared to local delivery.

b)

Higher dose will cause less systemic side effect in patients.

c)

The high blood flow on the eye allows higher delivery of drug to the organ.

2.

Which intraocular implant does not need to be removed after complete release of a drug?

a)

Nonbiodegradable implant

b)

Biodegradable implant

3.

Which of the following steps should be done to increase the local absorption of an eye drop?

(you can choose more than 1 answer)

a)

Immediately applying the second drop after the first drop.

b)

Preparing an eye drop with properties similar to the tears.

c)

Punctal occlusion.

d)

Blinking the eyes rapidly after the application of the eye drop.

4.

Which of the following statements is/are TRUE regarding an eye drop formulation?

(you can choose more than 1 answer)

a)

An eye drop solution will give a rapid onset of action.

b)

An eye drop suspension does not need to be readily dispersed upon shaking.

c)

An eye drop containing submicron emulsion is suitable for a hydrophilic drug.

d)

Eye ointment could provide sustained release of a drug.

5.

Which of the following dosage form(s) can be applied topically to the eyes?

(You can choose more than 1 answer)

a)

Implant

b)

Suspension

c)

Ointment

d)

Ion-exchange resin

6.

Which ophthalmic dosage form(s) can be used for a drug with poor water solubility?

(You can choose more than 1 answer)

a)

Solution

b)

Suspension

c)

Ointment

d)

Submicron Emulsion

7.

Which of the following conditions can cause an increased production of tears?

(you can choose more than 1 answer)

a)

A hypertonic solution

b)

A solution with a surface tension close to the tears

c)

A neutral solution

d)

highly viscous solution

8.

Which of the following vehicles is/are NOT buffered?

(you can choose more than 1 answer)

a)

Isotonic phosphate vehicle

b)

Special boric acid vehicle

c)

Boric acid vehicle

9.

Which of the following dosage forms is/are used for topical ophthalmic application?

(you can choose more than 1 answer)

a)

Intraocular implant

b)

Eye gels

c)

Eye powder

d)

Eye drops

e)

Eye lotion