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Nephrotic Syndrome

Total questions: 21

Worksheet time: 11mins

Name
Class
Date
1.

Nephrotic syndrome is more common in men than women

a)

TRUE

b)

FALSE

2.

In most children, the first sign of nephrotic syndrome is_

a)

Facial swelling

b)

High blood pressure

c)

Fatigue

d)

Diabetes

3.

Genetic mutation can lead to Nephrotic Syndrome

a)

TRUE

b)

FALSE

4.

Which of the following are primary causes of nephrotic syndrome?

I Minimal-change nephropathy

II Membranous nephropathy

III Diabetes Mellitus

IV Focal Glomerulosclerosis

a)

A. I,II,III

b)

B. II,III,IV

c)

C. I,II,IV

d)

D. All Above

5.

The most common causes of nephrotic syndrome in children is _

a)

Membranous nephropathy

b)

Focal segmental glomerulosclerosis

c)

Diabetes Mellitus

d)

Minimal change glomerulonephritis 

6.

Proteinuria lead/ reduce nephrotic syndrome.

a)

Lead

b)

Reduce

7.

Which of the following are possible symptoms and signs of nephrotic syndrome?

a)

Passing frothy and foul smelling urine

b)

Thrombosis

c)

Osteoarthritis

d)

Rheumatoid arthritis

8.

Oliguria is one of the symptoms of nephrotic syndrome. What is oliguria?

a)

Oliguria refers to the increase in the quantity (volume) of total urine output in a day.

b)

 Oliguria refers to the reduction in the quantity (volume) of total urine output in a day.

c)

Oliguria refers to presence of blood in the urine

d)

Oliguria refers to presence of protein in the urine

9.

The possible symptoms of nephrotic syndrome are edema, haematuria and oliguria.

a)

TRUE

b)

FALSE

10.

Which are from the following are the complications of nephrotic syndrome?

I Infections

II Thromboembolism

III Cardiovascular complications

IV Hypovolemic crisis

a)

I,II,III

b)

 II,III,IV

c)

 I,III,IV

d)

All Above

11.

---------------- is caused by increased glomerular permeability and hypoalbuminemia, resulting in decreased plasma oncotic pressure and functional hypovolemia.

Statement above is referring to which complications of nephrotic syndrome?

a)

Acute renal failure

b)

Edema

c)

Hormonal, mineral alterations and intussusceptions

d)

Anemia

12.

Why arterial punctures should be avoided in nephrotic children?

a)

Due to hyperlipidemia

b)

Due to the risk of arterial thrombosis

c)

Due to urinary loss

d)

Due to decreased of albumin level

13.

The complications of the NS can be divided into two categories, disease-associated and treatment-related.

a)

TRUE

b)

FALSE

14.

How does prognosis for patients with 

minimal change pathology always ends?

a)

GOOD

b)

FATAL

15.

How does prognosis for patients with 

Focal-segmental glomerulosclerosis always ends?

a)

GOOD

b)

FATAL

16.

A 6 year old child was brought to pediatric OPD with complaints of progressive swelling around the eyes which has progressed to involve the legs. Urine is positive for nephrotic range proteinuria but no hematuria. Serum albumin is low but she is otherwise well. Which of the following will NOT be part of the initial management?

a)

Salt restriction

b)

Diuretics

c)

Bed rest

d)

Low fat diet

17.

What is the most common drug that has been used for nephrotic syndrome?

a)

Corticosteroids

b)

Cyclophosphamide (CPM)

c)

Cyclosporin A (CsA)

d)

Tacrolimus

18.

How are children who develop NS being categorized by?

a)

History of disease/treatment

b)

Renal function

c)

Cyclosporine level

d)

Respond to corticosteroid therapy

19.

The presences of suppresser cytokines or lymphokines have been shown to have a role in the pathogenesis of the nephrotic syndrome

a)

TRUE

b)

FALSE

20.

In nephrotic syndrome, the rate of apoptosis in circulating (T-lymphocytes/ B-Lymphocytes) also has been found to be increased, and a role for reduced antioxidant defence has been postulated.

a)

B-lymphocytes

b)

T-lymphocytes

21.

Nephrotic syndrome is more common in adults compared to children.

a)

TRUE

b)

FALSE