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WorksheetsLipid transport and storage
Total questions: 15
Worksheet time: 11mins
Which of the following statements correctly describe the relationship between the density of lipoprotein and the lipid:protein proportion?
As the density of lipoprotein decreases, the lipid:protein proportion decreases
As the density of lipoprotein decreases, the lipid:protein proportion increases
As the density of lipoprotein decreases, the lipid:protein proportion stays the same
None of the above
Which of the following statements about apolipoproteins are false?
Synthesized in the RER and golgi bodies
Some kinds of apolipoproteins can transfer to another lipoproteins
One or more apolipoproteins may be present in each lipoprotein
A protein moiety of a lipoprotein constituting less HDL than chylomicrons
Which of the following Apolipoproteins can function as a ligand for LDL-receptor-related proteins?
Apo A
Apo B
Apo C
Apo D
Apo E
Which is the correct function of Apo A-II?
Inhibits lipoprotein lipase
Activates lecithin cholesterol acyl transferase
Inhibits lecithin cholesterol acyl transferase
Activates lipoprotein lipase
Which of the 4 types of lipoproteins are derived from the liver for triacylglycerol transport?
Chylomicrons
VLDL
LDL
HDL
1: Density is directly proportional to the TG content.
2: Density is inversely proportional to the size.
1 is true; 2 is false
1 is false; 2 is true
1 and 2 are true
1 and 2 are false
Which apolipoproteins are not associated with Chylomicrons?
Apo B-48
Apo C-II
Apo D
Apo E
Which of the following statements about VLDL is false?
Contains more triglycerides than cholesterol
Is associated with Apo B, Apo C-II and Apo E
Converted to IDL by phosphorylation
Can be found in chyle
Which of the following causes familial hypercholesterolemia?
Defect in Apo B-48
Defect in Apo B-100
Defect in Apo C-II
Defect in Apo D
Which is the correct order in lipid transport?
1: Excess cholesterol transported to the liver
2: Lipoprotein lipase releases fatty acids
3: Chylomicrons and VLDL are secreted into the bloodstream
4: VLDL is transformed to LDL
5: Tissues take up fatty acids
3 - 1 - 2- 5 - 4
5 - 2 - 3 - 4 - 1
3 - 2 - 5 - 4 - 1
4 - 3 - 5 - 1 - 2
Where is the main storage of triacylglycerol?
Intestines
Liver
Mitochondria
Adipose tissue
In the Lipolysis of triacylglycerol, glycerol can be utilized for the provision of G3P
True
False
Which inhibits lipolysis?
Epinephrine
Insulin
Growth Hormone
Vasopressin
Which of these drugs for hyperlipidemia are paired correctly with their mechanism?
Nicotinic acid: Activates peroxisome proliferator-activated receptor alpha
Bile Acid Sequestrants: Binds to LDL receptors on liver cells
Omega-3 Fatty Acids: Inhibits VLDL and triglyceride synthesis
PCSK9 Inhibitors: Inhibits hormone sensitive lipase
What is not a cause/category of fatty liver?
Raised level of plasma-free fatty acids
Metabolic block in production of plasma lipoproteins
Deficiency in Vitamin E
Absence of Orotic Acid
