WorksheetsExam 3
Total questions: 176
Worksheet time: 3hrs 56mins
Renal Fascia and Renal Capsule is made of?
dense irregular connective tissue
simple cuboidal
simple squamous
dense regular connective tissue
What are three distinct historical regions of kidney?
renal cortex
renal corpuscle
renal medulla
renal pelvis
How much ml of blood do kidneys receive per minute?
500 ml
1500 ml
1200 ml
100 ml
Put arteries in order
1. renal artery
2. interlobar artery
3. interlobular artery
4. arcuate artery
5. segmental artery
1, 5, 2, 4, 3
5, 2, 3, 4, 1
2, 5, 3, 1, 4
The renal corpuscle filters ___ and the renal tubule modifies filtrate into ____
(a)
Which of these is false about glomerulus?
fenestrated capillaries are extremely leaky
surrounded by bowman's capsule that is double layered
podocytes in the inner visceral layer
outer layer made of simple cuboidal epithelium
The outer parietal layer is extension of renal tubule made of simple ___ epithelium
cuboidal
squamous
columnar
Once the fluid reaches the ___, it is known as urine
proximal convoluted tubule
papillary collecting duct
minor calyx
Tubular secretion; fluid and solutes are reabsorbed from filtrate and returned to blood
True
False
Fenestrated glomerular capillary endothelial cells pass mostly ___ but ___ are too big to pass
(a)
Which of these is false about glomerular filtration?
about 20% of plasma becomes filtrate
hydrostatic pressure- force of fluid on capillary walls that pushes H20 out of capillary into interstitial space
colloid osmotic pressure is created by mostly albumin in plasma; osmotic gradient pulls H20 into blood capillaries by osmosis
mainly electrolytes
H20 moves into filtrate when hydrostatic pressure is ___ than colloid osmotic pressure
greater
less
H20 moves into plasma (blood) when colloid osmotic pressure is ___ than hydrostatic pressure
greater
less
Myogenic mechanism increases?
blood pH
systemic blood pressure stretches
blood flow
acidity
myogenic mechanism constrict afferent arteriole, ____ blood flow through glomerulus.
reduce
increase
if GFR increases, the filtrate volume goes __, and more Na+ and Cl- are absorbed into macula densa cells triggering release of paracrine signals.
down
up
Angiotensin II promotes
increased thirst
vasodilation of efferent arterioles and systemic blood vessels
vasocontriction of efferent arterioles and systemic blood vessels
reabsorption of Na+, Cl- and H20 from PCT
When blood pressure drops so does GFR, this causes the release of renin into blood stream from ___
JG cells
kidneys
proximal convoluted tubule
macula densa
___ are the female accessory glands while ___ are the male.
gonads, scrotum
mammary, prostate
ovary, testes
What are the gametes of males vs females?
(a)
GnRH comes from the ____ and targets the ____ ____ to stimulate the secretion of LH and ____.
hypothalamus, anterior pituitary, FSH
pons, posterior pituitary, renin
hypothalamus, midbrain, FSH
FSH comes from the ____ and targets the _____.
anterior pituitary, ovaries
anterior pituitary, testes
hypothalamus, testes
ovaries, fallopian tubes
Which hormone stimulates production of androgen- binding protein (ABP)?
GnRH
LH
FSH
Inhibin
LH comes from ___ and targets the ____ to stimulate the production and secretion of ____
anterior pituitary, testes, testosterone
posterior pituitary, ovaires, estrogen
hypothalamus, testes, testosterone
Which hormone is responsible for secondary sexual characteristics in male and female
testosterone, estrogen
testosterone, progesterone
progesterone, estrogen
GnRH is located in the _____ and targets the ___ ___. This stimulates the secretion of ___ and ___.
hypothalamus, ovarian follicles, LH and FSH
hypothalamus, anterior pituitary, LH and ABP
hypothalamus, anterior pituitary, LH and FSH
FSH targets the ___ and ____. It tells the follicles to start development and stimulate granulosa cells to convert androgens to ____.
ovarian follicles and granulosa cells, estrogens
mammary glands, luteum cells, estrogens
ovaries and granulosa cells, progesterone
What stimulates follicles to finish maturation after the 14th day of a woman's cycle?
LH
FSH
GnRH
Estrogens
The ovaries and granulosa cells are responsible for everything except?
estrogen
stimulate proliferation of endometrial cells
stimulate development of ducts of mammary glands
inhibit FSH secretion
sustentacular cells
Progesterone is sourced from?
ovaries (corpus luteum)
prostate
uterus
testes
Inhibin inhibits the secretion of?
LH
GnRH
FSH
___ protects and regulates temperature of testes
urethra
scrotum
ductus deferens
penis
Which of these is false?
bulbourethral gland secretes mucus and neutralize acidic traces of urine in urethra
prostate gland secretes slightly alkaline fluid with nutrients and helps sperm for fertilization
The testis do not produce inhibin
The epididymis promotes sperm cell maturation and stores sperm
What muscle is lining the scrotum?
dartos muscle
detrusor muscle
septum muscle
raphe muscle
Which smooth muscle controls the height of the testes?
dartos muscle
cremaster muscle
myoid muscle
The dartos muscle contracts to ___ surface area of scrotum when cold and relaxes when ____
reduce, warm
increase, warm
increase, cold
reduce, cold
Which of these is true?
seminiferous tubules contain two types of cells; spermatogenic and sustentacular cells
each testis is divided into septums
testes only have thermoreceptors for temperature
efferent ductules carry sperm from rete testis to the seminiferous tubules
Which cell contracts to push sperm and testicular fluid through tubules
myoid cells
interstitial cells
cremaster cell
sustentacular cells
The sight of sperm maturation and storage is the?
efferent ductules
epididymis
vas deferens
muscularis
Head receives ____ ductules from testis, which becomes called ductus epidiymis; long, coiled tube lined with ______ epithelial cells.
efferent, pseudostratified
efferent, simple squamous
afferent, pseudostratified
afferent, simple cuboidal
Ductus deferens can store sperm for ___ and ___ expired sperm
months, reabsorb
months, eject
years, reabsorb
days, filter
The seminal fluid is
yellowish secretion
makes up 60-70% semen volume
composed of fructose, prostaglandins, coagulating proteins, bases
Prostatic secretion makes up ___ of semen volume.
10-15%
20-30%
25-45%
60-70%
Prostatic secretion contains a milky fluid of
citrate
prostate specific antigen
acids
bases
antimicrobial chemicals
Membranous urethra passes ___ external urethral sphincter
in between
next to
down
through
What is another word for foreskin?
circumcision
spongiosum
prepuce
urogenital
There are __ corpora cavernosa and __ corpus spongism
1, 2
2, 1
2, 3
3, 1
Semen makes up about __% of semen volume and a typical ejaculate is between __-___ million sperm cells
5, 40-750
10, 10-100
15, 70-500
Semen will ___ to prevent it from leaking out of vagina.
coagulate
warm up
speed up
The process that prepares plasma membrane of sperm to penetrate and fertilize ova is?
penetration
clotting
correlation
capacitation
What allows sperm access further into female tract by contraction in female reproductive tract?
prostaglandins
antimicrobial chemicals
pH of semen
Process in which male gametes, or sperm cells are produced
spermatogonia
spermagenisis
spermatocyte
spermatids
Before puberty, spermatogonia ____. After puberty spermatogonia begin to produce ____ spermatocytes- ____
proliferate, primary, meiosis
fuse together, secondary, mitosis
When primary spermatocyte undergoes first meiotic division, it forms ___ smaller haploid cells called ___ spermatocytes
4, secondary
2, secondary
Sustentacular cells will:
form blood testis barrier
provide structural support
phagocytose
provide nutrients for dividing cells and produce androgen binding protein and inhibin
After meiosis I produces two haploid secondary spermatocytes, they undergo meiosis II to produce a total of ___ haploid spermatids.
1
3
4
6
Mitosis involves two ___ cells and meiosis involves 4 ___ cells.
diploid, haploid
haploid, diploid
LH stimulates ___ cells to produce testosterone and FSH stimulates ___ cells to secrete androgen binding protein.
interstitial, gonadotropin
interstitial, sustentacular
secondary, primary
Erythropoietin is stimulated to produce testosterone from the ___
kidneys
liver
hypothalamus
pituitary gland
Ejaculation is a ____ ____ process to expel semen
parasympathetic ANS
sympathetic ANS
sympathetic CNS
parasympathetic CNS
___ is a period in which reproductive functions begin to decline in males. The size of testes ____ and the number of sustentacular and interstitial cells ____.
andropause, decrease, decline
menopause, decrease, increase
During andropause, GnRH will ____ production of FSH and LH. The prostate gland experiences _____
increase, hypertrophy
decrease, hypertrophy
What is the percentage of all infertility cases due to males?
10%
50%
30%
40%
___ produces oocytes and estrogen, progesterone and inhibin, while the __ sustains embryo and sheds during menstrual flow
ovary, uterus
uterus, ovary
uterus, vagina
ovary, vagina
The wound consists of
body
tail
fundus
cervix
uterus
Outermost serous layer is the ___ while the ____ is the innermost layer that lines uterine cavity.
perimetrium, endometrium
myometrium, endometrium
cervix, ovaries
__ helps maintain acidic pH of vagina. Vaginal mucosa is composed of ___ squamous epithelium.
lactic acid, stratified
glycogen, pseudostratified
Epithelial cells secrete ___ into vaginal lumen
glucose
glycogen
amino acids
lipoproteins
___ is the incision made in tissues of perineum to prevent natural tearing during childbirth
epicotomy
vestibiotomy
episiotomy
endolobotomy
How many lobes radiate around and open into nipple?
15-25
25-30
40-50
9-10
Before birth, stem cells called ____ are formed to proliferate by ____
oogonia, meiosis
oogonia, mitosis
oocytosis, mitosis
oogenesis, meiosis
primary oocytes complete first meiotic division to produce __ haploid cells. Secondary oocyte contains most of ___ and proceeds to ____ II.
2, cytoplasm, metaphase
4, plasma, telephase
2, cytoplasm, anaphase
Which of these is incorrectly paired about spermatogenesis and oogenesis
spermatogenesis begins at puberty
oogenesis begins after birth
spermatogenesis continues until death
oogenesis produce one large oocyte each month
During luteal phase, ruptured follicle becomes an ____ organ called corpus ludeum
exocrine
endocrine
Corpus ____ are whitish knot of scar tissue left from old follicles after they cease secreting hormones
albicans
ludeum
follicle
Which of these is false about menses
first menses occurs approximately 2 years after onset of puberty
will not occur unless 15-17% body fat
require hormone leptin
GNRH levels increase which decrease levels of estrogen and progesterone
Follicular phase extends from day __ to ___ and luteal phase extends from day ___ to ___
1-14, 20-32
2-7, 9-15
1-14, 14-28
1-7, 10-24
Stratum functionalis sheds with a discharge of __-__ ml of blood
30-40
25-50
10-25
35-50
Female libido may be related to androgen DHEA produced by the
adrenal cortex
pituitary gland
kidneys
pons
Early menopause is occurrence of menopause before age of ___, while premature menopause occurs before age of ___.
45, 35
40, 45
40, 35
45, 40
Hormone imbalance of excessive androgens, interfere with normal ovulation is called
menopause
Polycystic ovarian syndrome
primary ovarian insufficiency
pelvic inflammatory disease
Most common viral infection is ___ ___ caused by over 40 different types of human papilloma
genital warts
endometriosis
uterine fibroids
aids
Genital herpes usually caused by herpes simplex virus type __, can be transmittable direct skin to skin contact.
1
2
3
chlamydia is a __ infection while trichomoniasis is a ___ infection.
bacterial, parasitic
parasitic, bacterial
Lesion called a canker is due to
chlamydia
gonorrhea
trichomoniasis
syphilis
Fluid balance is the study of maintaining appropriate ___ and concentration of body's ____ and extracellular fluids.
pH, intracellular
volume, intracellular
volume, plasma
Males have __ total body water, woman have ___ and infants have ___.
60, 50, 75
50, 75, 60
60, 75, 50
35, 40, 60
Intracellular fluid is more than interstitial fluid
true
false
Electrolytes are substances that dissociate into ___ and have a ___ particles. Non-electrolytes have strongest ___ bonds and have ___ charge.
ions, charged, covalent, no
ions, non charged, noncovalent, positive
Protein content is high in the ___, and almost zero in the ____
interstitial fluid, intracellular fluid
plasma, intracellular fluid
plasma, interstitial fluid
interstitial fluid, plasma
Sodium contains more ___, potassium contains more ____
plasma, interstitial fluid
plasma, intracellular fluid
intracellular fluid, interstitial fluid
interstitial fluid, plasma
Usually ___ cannot move freely and need a transport protein while ___ can move freely due to ___
ions, h20, hydrostatic pressure
solutes, proteins, osmosis
solutes, h20, osmosis
Osmotic pressure gradient; force of solutes that tends to pull h20 toward solution with ___ osmotic pressure.
higher
lower
Hydrostatic pressure gradient; force that fluid exerts on cells; tends to push h20 ___ from area of higher hydrostatic pressure
away
toward
Drinking a lot of fluid may cause ____ plasma
hypotonic
hypertonic
isotonic
Plasma may result from sweating a lot called
hypertonic
hypotonic
isotonic
Easiest source of water is ___ and the best way to expel it out is through ____
drinking, urination
drinking, perspiration
food, respiration
metabolism, defecation
About ___ ml of urine needs to be produced daily to prevent toxic buildup of molecules
100
200
300
500
ADH is produced in the ____ and released from ____.
DCT, posterior pituitary
hypothalamus, posterior pituitary
hypothalamus, anterior pituitary
DCT, collecting ducts
All of these except ___ are involved in fluid balance
aldosterone
angiotensin-II
ADH
ANP
renin
When dehydrated, volume ___ and ECF concentration ___
decreases, increases
increases, increases
increases, decreases
If you vomit, h20 loss ___ plasma volume and ___ solute concentration
increases, increases
decreases, decreases
decreases, increases
increases, decreases
___ enhances thirst sensation
aldosterone
angiotensin-II
ANP
creatine
Drinking more water after detecting dehydration is a ___ feedback loop
negative
positive
Losing mainly fluid is known as h__natremia while losing mainly sodium is known as h__natremia
hypo, hyper
hyper, hypo
Dehydration causes a ___ in blood volume/pressure and an ___ in Na+ concentration
decrease, increase
decrease, decrease
increase, decrease
increase, increase
Angiotensin II causes
vasocontriction
vasodilation
decrease in water intake
decrease in Na+ reabsorption
During overhydration (hypotonic), volume is ___ and concentration of ECF is ___.
increased, decreased
decreased, increased
When osmotic pressure of plasma decreases, H20 moves ___ cell by osmosis
into
out of
in between
Bleeding can cause
hypervolemia
hypovolemia
hypertonicity
Hypervolemia is fluid excess, exists when ECF volume ___ without a change in osmotic pressure
decreases
increases
stays the same
The most abundant extracellular cation is
Na+
K+
Mg+
Proteins
ANP increases Na+ ___ while angiotensin-II and aldosterone increase Na+ ____
reabsorption, filtration
reabsorption, secretion
reabsorption, dehydration
secretion, reabsorption
Hypernatremia is elevated Na+ concentration; greater than __ mEq/I caused by dehydration, while hyponatreamia is decreased Na+ concentration; less than ___ mEq/I caused by overhydration
120, 135
140,130
145,135
When Na+ levels in the __ decrease, receptors in the macula densa activate ___
ECF, RAAS
ICF, RAAS
Most abundant intracellular cation is?
Na+
K+
Mg+
Cl-
When K+ rushes out of the cell, cytosol becomes ___ positive
less
more
Which of these is false about potassium
When you urinate, potassium needs to be taken to replenish it being lost
insulin, aldosterone and epinephrine are hormones that stimulate uptake of k+ by cells
excess k+ is reabsorbed into blood
hypocalcemia is commonly caused by diuretics that lead to excess k+ loss in urine
Calcium is a ___cellular __ion , while phosphorus is a ___cellular ___ion
extracellular cation, intracellular anion
intracellular anion, extracellular anion
extracellular anion, intracellular cation
When ECF Ca2+ levels drop, Ca2+ is released from bone tissue by osteo___
clasts
blasts
When Ca2+ is deposited in bone tissue it is due to osteo_
blast
clast
mast
Calcitonin is released by the ___ gland
pituitary
parathyroid
thyroid
PTH activates vitamin
A
C
D
K
The release of PTH by the parathyroid gland stimulates Ca2+
release from bones
into the bones
Increase in calcium uptake in ___ activates vitamin D and increases calcium uptake in ___
kidneys, liver
kidneys, intestines
intestines, kidneys
liver, kidneys
Hypercalcemia leads to all of the following except
vitamin D loss
bone disorder
renal failure
neurons become less permeable to Na+
Hypocalcemia leads to a ___ in vitamin D
loss
gain
CL- is an ___cellular ___ion while Mg2+ is a ___cellular ___ion
extracellular anion, intracellular cation
intracellular anion, extracellular cation
extracellular cation, intracellular anion
intracellular cation, intracellular cation
High levels of magnesium block calcium entry into cells and can lead to ___calcemia
hypo
hyper
pH is the measure of ___ in a solution
protons
ions
cation
electrolytes
HCO3- is a ___ and H2CO3 and HCl is ___
base, acid
acid, base
Normal pH range of bodily fluid is 7.__ - 7.__
7.25-7.45
7.35-7.45
7.50-7.65
7.15-7.45
Which is false
ketoacids are formed by fats and amino acid catabolism
lactic acid is byproduct of fermentation of pyruvate
uric acid is formed by catabolism of nucleic acids
body pH is slightly acidic
H+ is put into ___ and HCO3- goes into ___.
urine, blood
blood, urine
urine, kidney
Phosphate buffer system primarily functions in the __ tubules of ICF
plasma
renal
distal convoluted
proximal
When you vomit this is due to ____, ___ pH and HCO3-
metabolic alkalosis, increase
metabolic acidosis, decrease
respiratory acidosis, increase
respiratory alkalosis, increase
Diarrhea is due to metabolic ____ and ___ pH and HCO3-
alkalosis, decrease
acidosis, decrease
acidosis, increase
alkalosis, increase
Decreased gas exchange in the alveoli is due to respiratory ____ which is a ___ in pH and a _____ Pco2
acidosis, decrease, increase
acidosis, increase, decrease
alkalosis, decrease, decrease
alkalosis, increase, increase
Respiratory alkalosis is a __ in pH and ___ in Pco2, hyperventilation due to high altitudes and ___ atmospheric Po2.
increase, decrease, high
decrease, decrease, low
decrease, increase, high
increase, decrease, low
Fully compensated imbalance means
pH is normal but PCO2 and HCO3- levels are abnormal
pH is abnormal and PCO2 while HCo3- is normal
HCO3 and PCO2 are normal while pH is abnormal
Anchoring the peritoneum is due to the renal ___ and a thin layer that surrounds kidney is the renal ___
capsule, fascia
fascia, capsule
The most deep layer of kidney is
renal fascia
adipose capsule
renal capsule
Renal columns are locating in the renal ___ and renal pyramids are locating in the renal ___
cortex, pelvis
medulla, pelvis
medulla, cortex
cortex, medulla
Renal ___ drains urine into the ureter
papilla
medulla
cortex
pelvis
Descending limb is made of ___ epithelial cells
simple
pseudo stratified
transitional
stratified
Ascending limb becomes simple ___ epithelial cell
columnar
cuboidal
stratified
What regulates blood pressure and glomerular filtration rate
macula densa
juxtaglomerular cells
DCT
brush border
Cortical nephrons make up ___% of nephrons and Juxtamedullary nephrons make up __%..
20, 80
40, 60
80, 20
70, 30
Which of these is true about glomerular filtration
lipoproteins can pass
visceral layer is the 2nd barrier
basement membrane/ basal lamina is the 1st barrier
looping structure of glomerular capillaries increases surface area
Collagen is important because
it forms finger-like extensions of podocytes that wrap around glomerular capillary
forms web that blocks large substances and have negative charge that repel other negatively charged substances
allows proteins to pass
How many nitrogenous wastes are produced in glomerular filtration?
4
2
3
1
Colloid pressure is created by proteins, mostly ____ in plasma. The osmotic gradient pulls H20 into blood ____ by osmosis
enzymes, lymph
amino acids, capillaries
albumins, capillaries
Hydrostatic pressure is the force of fluid on capillary ___; pushes H20 out of capillary into ____
walls, interstitial space
walls, intercellular space
space, extracellular space
Water moves into filtrate when hydrostatic pressure is ___ than COP. Water moves into plasma when COP is ___ than hydrostatic pressure
lower, higher
higher, lower
higher, higher
lower, lower
How do you calculate NFP?
GHP+(GCOP+CHP)
CHP-( GHP+GCOP)
GHP+(GCOP-CHP)
GHP-(GCOP+CHP)
When afferent arterioles ____, it ___ systemic blood pressure and ___ GFR
constrict, increase, increase
constrict, decrease, increase
dilate, increase, increase
dilate, decrease, decrease
JGA regulates
blood pressure only
glomerular filtration rate only
both
neither
Macula densa is found in
afferent arterioles
efferent arterioles
PCT
renal tubule
afferent and efferent arterioles
Syndrome of inappropriate ADH secretion is a result of excess fluid retention that leads to ___ in plasma osmolarity and a ___ in urine osmolarity
decreased, increased
increased, decreased
decreased, decreased
increased, increased
Excess ADH is caused by ___ tumors
liver
lung
kidney
heart
Inflammation of glomerular capillaries and basement membrane causes ___ in blood flow and capillary permeability; ____ GHP
increase, increase
decrease, decrease
increase, decrease
decrease, increase
Kidney stones are composed of ___ ___ salts
calcium oxalate
calcium nitrate
sodium chloride
sodium oxalate
Crystals can form in the
nephron loop
PCT
DCT
collecting system
glomerulus
___ motor fibers stimulate detrusor muscle to contract and ___ urethral sphincter to relax
efferent, external
efferent, internal
afferent, internal
afferent, external
The micturition center is found in the ___ and the reflex arc is mediated by the ____ ANS.
pons, parasympathetic
midbrain, parasympathetic
hypothalamus, parasympathetic
The detrusor muscle is ____ smooth muscle.
voluntary
involuntary
Antidiuretic and aldosterone promote
concentrated urine
less concentrated urine
If body is dehydrated, urine is ___. If there is excess h20, ___ h20 is reabsorbed and urine is ____
concentrated, less, concentrated
dilute, more, concentrated
concentrated, less, dilute
dilute, more, dilute
Aquaporins:
decrease movement of water
increase movement of water
are only found in apical membranes
decrease filtrate rate
if blood pH increases, HCO3- is reabsorbed ___. When blood pH decreases, it becomes too __.
more, acidic
less, acidic
more, basic
less, basic
PCT helps:
maintain acid-base homeostasis
excrete toxins
reabsorb H+ into blood
filter albumin
If there is too much glucose in the filtrate this is called
glycosuria
hyperglycemia
glyconatremia
hypertension
Macula densa sends signals to JG cells causing ___ renin release, which allows efferent arterioles to ___ causing a ___ in GFR
increase, constrict, decrease
increase, dilate, increase
reduced, constrict, increase
reduced, dilate, decrease
When GFR increases, this causes afferent arterioles to ___. This is the ____
constrict, myogenic mechanism
constrict, tubuloglomerular feedback
dialate, myogenic mechanism
dialate, autoregulation
RAAS stands for
renin-angiotensin- antidiuretic system
renin- angiotensin II- aldosterone system
renin- angiotensin- aldosterone syndrome
renin- angiotensin- aldosterone system
___ in blood flow through ___ arteriole triggers JG cells to release renin into blood system
reduction, afferent
increase, afferent
reduction, efferent
increase, efferent
