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WorksheetsDNA replication
Total questions: 11
Worksheet time: 7mins
Which of the following statements best explains the mechanism for DNA replication?
DNA replication is reductive, because half the total DNA present is copied.
DNA replication is semi-conservative, because each DNA strand serves as a template during replication.
DNA replication is dispersive, because the two resulting DNA molecules are mixtures of parent and daughter DNA.
DNA replication is conservative, because one resulting molecule is identical to the original and the other consists of two new strands.
In DNA replication, DNA "unwinds" to form two template strands: the leading strand and the lagging strand.
Which of the following statements about these strands is true?
Okazaki fragments are used to synthesize the leading strand of DNA.
The leading strand of DNA is synthesized continuously.
DNA polymerase can only synthesize DNA on the leading strand.
The lagging strand can only be synthesized once the leading strand has been completed.
There are several DNA repair mechanisms in place to help detect and correct DNA damage.
Which of the following is true regarding these DNA repair mechanisms?
DNA damage from chemical reactions cannot be undone.
Proofreading from DNA polymerase reduces the error rate in DNA to about 1 in 100 nucleotides.
Copying errors not caught by the replication machinery can be corrected by mismatch repair.
Non-homologous end joining is less likely to produce mutations than homologous recombination.
A template strand of DNA is 3′ TAGGCATTGCA 5′, .
What is the complementary DNA strand that is created from this template during replication?
5′ TAGGCATTGCA 3′
5′ ATCCGTAACGT 3′
5′ AUCCGUAACGU 3′
5′ TGCAATGCCTA 3′
There are several enzymes involved in DNA replication.
Which of the following correctly pairs the DNA replication enzyme with its function?
Topoisomerases work ahead of the replication fork to prevent supercoiling.
DNA polymerase I opens up the DNA at the replication fork.
Helicase seals gaps between DNA fragments.
DNA primase extends primers by adding nucleotides to the 3'3′3, prime end.
Which of the following separates DNA into single-strands?
DNA polymerase
DNA gyrase
DNA helicase
DNA ligase
Which of the following is used to remove the RNA primer from Okazaki fragments?
DNA polymerase I
DNA polymerase II
DNA polymerase III
DNA ligase
Which of the following has 3' to 5' polymerase activity?
DNA polymerase I
DNA polymerase II
DNA polymerase III
none of these
The picture below shows an enzyme unwinding and unzipping DNA.
What is the name of this enzyme?
DNA Helicase
DNA polyermase
DNA Ligase
RNA Polymerase
Okazaki fragments appear on which strand of DNA during DNA replication?
Leading
Lagging
Where does DNA replication take place?
Nucleus
Cytoplasm
Ribosome
Golgi Body
